Curriculum Vitae
Ph.D. Guangdi Li
Guangdi Li received his doctoral degree in Biomedical Sciences from the Faculty of Medicine, KU Leuven, Belgium, 2014. During his Ph.D., he received extensive training from Master of Molecular and Cellular Biophysics, Faculty of Science, KU Leuven. In 2006, he obtained his Bachelor's degree in Applied Mathematics at Hunan University. Between 2006 and 2009, he pursued his master’s degree in Computer Science at Shandong University, and received full scholarships to work as a research assistant at the Technical University of Madrid, Spain. Between 2009 and 2014, he undertook his doctorate training in the Faculty of medicine, KU Leuven, Belgium. His research interests are focused on the genome-wide diversity, coevolution and interaction of HIV, HBV and HCV, as well as the development of antiviral drugs and vaccines. Since 2013, he has published more than 10 research articles.
My Publications
Current address: Metabolic Syndrome Research Center, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Email: liguangdi.research@gmail.com
My Education
| Phd in Biomedical Sciences, Rega Institute for Medical Research, Faculty of Medicine, KU Leuven (established in 1425), Leuven, Belgium. My Phd thesis is entitled: "HIV genome-wide diversity, interaction and coevolution".  |
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| Master in Molecular and Cellular Biophysics, Faculty of Science, KU Leuven (established in 1425), Leuven, Belgium My supervisor is: Prof. Marc De Maeyer  |
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| Research assistant in Department of Artificial Intelligence, School of Computer Engineering, Technical University of Madrid (established in 1971), Madrid, Spain. My supervisors are: Prof. Concha Bielza and Prof. Pedro Larrañaga.  |
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| Master in Computer Science and Technology, School of Computer Science and Technology, Shangdong University (established in 1901), Jinan, Shandong, China My supervisor is: Prof. Daming Zhu  |
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Bachelor in Mathematics and Applied Mathematics, College of Mathematics and Econometrics, Hunan University (established in 976), Changsha, Hunan, China  |
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Junior student in The High School Attached To Hunan Normal University (established in 1905), Changsha, Hunan, China
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Pupil in The Elementary School of Chang Mao Ling (established in 1940), Changsha, Hunan, China. |
Here is my Phd thesis (418 pages):
"HIV genome-wide diversity, interaction and coevolution"
My Professorships
| Associate Research Fellow in Metabolic Syndrome Research Center, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China 副研究员，中南大学湘雅二医院代谢综合征研究中心，中国湖南长沙。 |
My research interets
- Infection diseases.
- Genome-wide diversity, interaction and coevolution.
- Antiviral drugs.
- Virus-host protein interactions.
- Bioinformatics and Computational biology.
- Molecular and structural biology.
- Software design.
My research funding
Principal Investigator of the following research grants
| Title: Investigation of HIV genome-wide protein interactions using systems biology methods （基于系统生物学的HIV全基因组蛋白交互机制研究）. Approved by: National Nature Science Foundation of China (ID:31571368)；国家自然科学常规面上基金（项目批准号：31571368）. Research budget: 680 000 yuan （68万元人民币） |
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| Title: Investigation of HIV genome-wide protein interactions（HIV全基因组蛋白交互机制研究）. Approved by: Innovation-driven Foundation of Central South University；中南大学“创新驱动计划”项目基金（注：项目负责人应具有副教授及以上相当技术职称，年龄不超过40周岁）. Research budget: 600 000 yuan （60万元人民币） |
My research skills
| Chinese, English. | Matlab, R, C, C++, HTML, JSP, Perl, SQL. |
| Molecular structure: PyMOL, Chimera, MOE | |
| Sequence analysis: Seaview, Mega | |
| Phylogenetic analysis: FastTree, HyPhy, RAxML, SplitTree | |
| Statistic analysis: Matlab, R | |
| Evolutionary analysis: ECS | |
| Powerpoint, Photoshop, Adobe Illustrator, Circos, Genomi |
Awards and Honors
| The first prize of China Postgraduate Mathematical Contest in Modeling (CPMCM), China. | |
| Scholarship awarded by Universidad Politecnica De Madrid (12 000 euros). | |
| The second prize of National English Competition. | |
| The second scholarship and Triple Excellence awarded by Hunan University. | |
| The first prize of Mathematical Modeling Competition, Hunan University. | |
| The second scholarship and Triple Excellence awarded by Hunan University. | |
| The third prize of Mathematical Modeling Competition, Hunan Province. | |
| The third scholarship awarded by Hunan University. |
Conference Talks
| Guangdi Li, SamadAmini-Bavil-Olyaee, Thomas Mina, Philippe Lemey, Piet Maes, Marc Van Ranst, MahmoudrezaPourkarim. | |
| HBV genome-wide diversity from the world population perspective | |
| 6th International Tehran Hepatitis Conference, Tehran, Iran. | |
| Guangdi Li, Anne-Mieke Vandamme, Jan Ramon. | |
| Learning Ancestral Polytrees | |
| The workshop of Learning Tractable Probabilistic Model, Beijing, China. | |
| Mónica Eusébio, Raf Winand, Andrea-Clemencia Pineda-Peña, Guangdi Li, Kristel Van Laethem, Ricardo Camacho, Anne-Mieke Vandamme, Ana Abecasis. | |
| Transmission clusters of drug resistance in subtype B in Portugal. | |
| The 12th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, Barcelona, Spain. | |
| Andrea-Clemencia Pineda-Peña, Yoeri Schrooten, Lore Vinken, Fossie Ferreira, Guangdi Li, Nídia Sequeira Trovão, Ricardo Khouri , Inge Derdelinckx, Paul De Munter, Claudia Kücherer, Leondios G. Kostrikis, Claus Nielsen, Kirsi Liitsola, Claudia Balotta, Annemarie Wensing ,Maja Stanojevic, Roger Paredes, Jan Albert, Charles Boucher, Arley Gomez-Lopez, Eric Van Wijngaerden, Marc Van Ranst, Jurgen Vercauteren, Kristel Van Laethem, Anne-Mieke Vandamme. | |
| Predictors of HIV-1 transmitted drug resistance and transmission networks in the Leuven cohort. | |
| The 12th European Meeting on HIV & Hepatitis - Treatment Strategies & Antiviral Drug Resistance, Barcelona, Spain. | |
| Guangdi Li, Jens Verheyen, Soo-Yon Rhee, Arnout Voet, Mónica Eusébio, Anne-Mieke Vandamme, Kristof Theys. | |
| Functional conservation of HIV-1 gag: implications for rational drug design. | |
| The 14th European AIDS Conference, Brussels, Belgium. | |
| Guangdi Li, Jens Verheyen, Jan Ramon, Mónica Eusébio, Kristof Theys, Anne-Mieke Vandamme. | |
| The HIV-1 Gag and protease coevolution networks. | |
| The 14th European AIDS Conference, Brussels, Belgium. | |
| Guangdi Li, Supinya Piampongsant, Philippe Lemey, Anne-Mieke Vandamme, Kristof Theys. | |
| Quantification of HIV genome-wide diversity. | |
| Infectious Disease Genomics & Global Health conference, Cambridge, UK. | |
| Andrea-Clemencia Pineda-Peña, Nuno Rodrigues Faria, Francisco-Javier Diaz, Patricia Olaya, Casper Møller Frederiksen, Guangdi Li, Arley Gomez-Lopez, Philippe Lemey, Anne-Mieke Vandamme. | |
| The colombian epidemic is dominated by HIV-1 subtype B: a molecular epidemiology and phylodynamic study. | |
| The 20th International HIV Dynamics and Evolution conference, Utrecht, Netherland. | |
| Mónica Eusébio, Raf Winand, Andrea-Clemencia Pineda-Peña, Guangdi Li, Kristel Van Laethem, Ricardo Camacho, Anne-Mieke Vandamme, Ana Abecasis. | |
| Significantly different TDR levels and mutation patterns in HIV-1 subtype G compared to subtype B in Portugal. | |
| The 14th European AIDS Conference, Brussels, Belgium. | |
| Guangdi Li, Gertjan Beheydt, Concha Bielza, Pedro Larrañaga, Ricardo Camacho,Zehava Grossman, Carlo Torti, Maurizio Zazzi, Mattia Prosperi, Rolf Kaiser, Kristel Van Laethem, Marc De Maeyer, Anne-Mieke Vandamme. | |
| Learning ancestral polytrees for HIV-1 mutation pathways against protease inhibitor Nelfinavir. | |
| The 9th European Conference on Computational Biology (ECCB), Gent, Belgium. | |
| Guangdi Li, Gertjan beheydt, Ricardo Camacho, Anne-Mieke Vandamme, Kristof Theys. | |
| Analysis of HIV-1 resistance pathways using multi-polytree: implications of multiple HIV-1 mutation pathways. | |
| The 10th Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (MEEGID), Amsterdam, The Netherlands. | |
| Guangdi Li, Gertjan Beheydt, Concha Bielza, Pedro Larrañaga, Ricardo Camacho,Zehava Grossman, Carlo Torti, Maurizio Zazzi, Mattia Prosperi, Rolf Kaiser, Kristel Van Laethem, Marc De Maeyer, Anne-Mieke Vandamme. | |
| Learning ancestral polytrees for HIV-1 mutation pathways against nelfinavir. | |
| IAP meeting, Ghent, Beligum. | |
| Guangdi Li, Concha Bielza, Pedro Larrañaga | |
| Learning causal polytree structure for HIV mutation patterns. | |
| The 15th International Bio-Informatics Workshop on Virus Evolution and Molecular Epidemiology, Rotterdam, The Netherlands. |
Pictures of my life
In 2014, Prof. Erik De Clercq (middle), Mrs. Renilde Loeckx (Honorary Ambassador, right) and I (left) were together in front of Rega institute, Leuven.
In 2013, I was together with my colleagues in lab had a team building day, Belgium.
In 2007 and 2008, I recieved twice the scholarship awarded by Universidad Politécnica de Madrid Sino-Spanish Scholarship Program.
In 2008, Prof. Pedro Larrañaga (left), Prof. Concha Bielza(left center), Dr. Hanen Borchani (right center) and I (right) took a holiday tour in Madrid, Spain.
In 2009, I arrived in Belgium to pursue my Phd.
In 2010, I visited the castle of KU Leuven in winter.
On August 28, 2014, I passed my Phd defense and received the Phd degree in Biomedical Sciences.
