Mechanisms of drug action
Here, we share the movies to show how antiviral drugs bind to their protein targets.
See quick selections on left side bar.
- Sofosbuvir
- Name: Sofosbuvir
- Approved date: December 2013
- Drug action: It binds to two Mg2+ ions in HCV NS5B polymerase and inhibits RNA replication.
- Pubchem link: 45375808
- Drug bank link: DB08934
- PDB structure link: 4WTG
Antiviral drug history
As of September 2015, 60 antiviral drugs have been approved for clinical use. Please click the following picture for more drug movies.
