| Year |
Conference and course talks |
| 6 January 2015 |
“Ebola: multiple opportunities for therapeutic intervention”, School of Public Health, HKU Medical Campus, University of Hong Kong (hosts: Professor JSM (Malik) Peiris (Director, Chair of Virology, Tam Wah-Ching Professor in Medical Science) and Hui-Ling Yen, Assistant Professor). |
| 15-16 December 2014 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Students’ examinations. |
|
| 25-26 November 2014 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| Lesson 21: Dancing with antiviral drugs (part A) |
| Lesson 22: Dancing with antiviral drugs (part B) |
| Lesson 23: Clinical case reports in antiviral chemotherapy: VZV, HSV, HPV, MCV, Orf, HPV, EBV, SIV, HBV, HBV. |
| Lecture delivered on “Ebola: Multiple opportunities for therapeutic intervention” at the University of South Bohemia, Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector of the University of South Bohemia. |
| 4-5 November 2014 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 12: Vitamins (A, B, C, D, E, …) (parts 1 and 2): structure, synthesis, mechanism of action, pathology associated with hypo- and hypervitaminoses. Case report 15. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| 21-22 October 2014 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 7a: Biosynthesis of cholesterol. |
| Lesson 7b: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. Case report 6. |
| Lesson 8: Muscle/kidney. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle, NO formation. Case report 7. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …), Case report 8, -aminobutyric acid (GABA). Case report 9. |
| Lesson 11a,b: Hormones (thyroid hormone, Case report 10, parathyroid hormone, insulin, Case report 11, glucagon, catecholamines, Case report 12, phenylketonurian glycogen storage, Case report 13, steroid hormones, congenital adrenal hyperplasia, Case report 14, pituitary gland hormones, hypothalamus hormones, gastrointestinal hormones; for all hormones: structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). |
| 7-8 October 2014 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h) at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Case report 1 – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Case report 2 – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. |
| Lesson 4: Biosynthesis of heme, Lead poisoning, Case report 3, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. Case report 4. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. Case report 5. |
| Lesson 6a: Degradation of heme, Formation of CO, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| Lesson 6b: Biosynthesis and biological role of bile acids. |
| 29-30 July 2014 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 24 March 2014 |
“The race in the development of DAAs (direct-acting antivirals) for treatment of hepatitis C”, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong (host: Professor Henry L.Y. Chan, Head of Division of Gastroenterology and Hepatology, Assistant Dean of Faculty of Medicine, The Chinese University of Hong Kong). |
| 11 March 2014 |
Scientific Discussions, Scientific Council, Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCL), Woluwé, Brussels, Belgium. |
| 18 December 2013 |
“Current antiviral drug development”, University of South Bohemia in Ceské Budĕjovice, Biology Center of the Academy of Sciences of the Czech Republic (host: Prof. Dr. Libor Grubhoffer, Rector of the University of South Bohemia in Ceské Budĕjovice). |
| 17-18 December 2013 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Students’ examinations. |
| Lecture delivered on “Current trends in antiviral drug development” at the University of South Bohemia, Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector of the University of South Bohemia. |
| 13 December 2013 |
“Dancing with chemical formule of antivirals: a panoramic view”, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea (host: Prof. Eui-Cheol Shin, Korea Advanced Institute of Science and Technology, Daejeon, Korea). |
| 11 December 2013 |
“Dancing with chemical formulae of antivirals: a personal account”, Seoul National University, College of Pharmacy (host: Prof. Dr. Lak Shin Jeong, College of Pharmacy, Seoul National University, Seoul, Korea). |
| 28-29 November 2013 |
Lectures delivered at Palacký University, Olomouc, Czech Republic |
| - “Dancing with chemical formulae of antivirals: a personal account ( part A)” |
| - “Dancing with chemical formulae of antivirals: a personal view (part B)” |
| - “Current trends in antiviral drug development” |
| (host: Prof. Dr. Petr Fryčák, Palacký University, Olomouc, Czech Republic) |
| 26-27 November 2013 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| Lesson 21: Clinical case reports in antiviral chemotherapy: VZV, HSV, HPV, MCV, Orf, HPV, EBV, SIV, HBV, HBV. |
| 12-13 November 2013 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 12: Vitamins (A, B, C, D, E, …) (parts 1 and 2): structure, synthesis, mechanism of action, pathology associated with hypo- and hypervitaminoses. Case report 15. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| 4 November 2013 |
“Current development of antiviral agents”, Shandong University, Jinan, P.R. China (host: Prof. Dr. Xinyong Liu, Director of the Institute of Medicinal Chemistry, Vice Dean of School of Pharmaceutical Sciences, Shandong University). |
| 22-23 October 2013 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 7b: Biosynthesis of cholesterol. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. Case report 6. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. Case report 7. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …). Case reports 8 and 9. |
| Lesson 11 (parts 1, 2, 3 and 4): Hormones (thyroid hormone, parathyroid hormone, insulin, glucagon, catecholamines, steroid hormones, pituitary gland hormones, hypothalamus hormones, gastrointestinal hormones: structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). Case reports 10-14. |
| 15-16 October 2013 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h) at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. Case report 1. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). Case report 2. |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. Case report 3. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. Case report 4. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. Case report 5. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| Lesson 7a: Biosynthesis and biological role of bile acids. |
| 30 September 2013 |
Scientific Advisory Board (SAB) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 6 September 2013 |
“Current highlights in antiviral drug development”, Palacky University, Olomouc, Czech Republic (host: J. Hlavac, Professor at Palacky University). |
| 31 July-1 August 2013 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 21 May 2013 |
“Dancing with chemical structures: antivirals”, Department of Pharmacology and Pharmacy, The University of Hong Kong (host: Prof. Dr. Paul Vanhoutte, Chair Professor, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong). |
| 5 April 2013 |
“Dancing with molecules: antivirals”, Department of Chemistry, Fudan University, Shanghai City, P.R. China (host: Prof. Fen-Er Chen, Fudan University, Shanghai). |
| 4 April 2013 |
“Current state of the art on antiviral drug development”, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China (host: Prof. Guanhua Du, Director, President Chinese Pharmacological Society; and Prof. Fen-Er Chen, Fudan University, Shanghai). |
| May 2013 |
Henry Stewart Talks. The Biomedical & Life Sciences Collection. |
| Series: Antivirals, edited by E. De Clercq. |
| “Key drug discovery challenges in antivirals”. |
| 18-19 December 2012 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Students’ examinations. |
| Lecture delivered on “Current trends in antiviral drug development” at the University of South Bohemia, Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector of the University of South Bohemia. |
| 4-5 December 2012 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| Lessons 21-25: Clinical case reports in antiviral chemotherapy: VZV, HSV, HPV, MCV, Orf, HPV, EBV, SIV, HBV, HBV. |
| 27-28 November 2012 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 12: Vitamins (A, B, C, D, E, …) (parts 1 and 2): structure, synthesis, mechanism of action, pathology associated with hypo- and hypervitaminoses. Case report 15. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| 6-7 November 2012 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. Case report 6. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. Case report 7. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …). Case reports 8 and 9. |
| Lesson 11 (parts 1, 2, 3 and 4): Hormones (thyroid hormone, parathyroid hormone, insulin, glucagon, catecholamines, steroid hormones, pituitary gland hormones, hypothalamus hormones, gastrointestinal hormones: structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). Case reports 10-14. |
| 30-31 October 2012 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h) at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Rector, University of South Bohemia, Czech Republic. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. Case report 1. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). Case report 2. |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. Case report 3. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. Case report 4. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. Case report 5. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| Lesson 7: Biosynthesis and biological role of bile acids. Biosynthesis of cholesterol. |
| 19 October 2012 |
“Human viral diseases: what is next for antiviral drug discovery”, Division of Internal Medicine, Korea University College of Medicine, Seoul, South Korea (host: Prof. Dr. Woo Joo Kim, Professor, Korea University College of Medicine (KUCM), President, Transgovernmental Enterprise for Pandemic Influenza of Korea (TEPIK). |
| 17 October 2012 |
“Human viral diseases: what is next for antiviral drug discovery”, Korea Research Institute of Chemical Technology (KRICT), Daejeon, South Korea (host: Dr. Chong-Kyo Lee, Team Leader, Principal Research Scientist). |
| 29-31 July 2012 |
“The past and present of the acyclic nucleoside phosphonates. The Holý Trinity” (invited lecture), Deutsches Krebsforschungszentrum (DKFZ), German Cancer Research Center, Advances in Infection and Cancer, Heidelberg, Germany (hosts: Prof. Dr. Otmar D. Wiestler, Chairman and Scientific Director of the DKDFZ, and Prof. Dr. Harald zur Hausen,; Former Chairman and Scientific Director of DKFZ). |
| 31 July-1 August 2012 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 24 July 2012 |
Allocution at the funeral of Prof. Antonin Holý [former Director of the Institute of Organic Chemistry and Biochemicals (IOCB)], Prague, Czech Republic. |
| 11 June 2012 |
Scientific Advisory Board (SAB) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 10 May 2012 |
Allocution (Laudatio) at the occasion of the election of Prof. Dr. Libor Grubhoffer as Rector of the University of South Bohemia in Ceské Budĕjovice (host: Prof. Dr. Libor Grubhoffer). |
| 20-21 December 2011 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Students’ examinations |
| 19 December 2011 |
Opening of the first Austria Czech NMR Research Center, European Territorial Cooperation (ETC) of the European Union between the Johannes Kepler University in Linz (JKU) and the University of South Bohemia in Ceské Budĕjovice (USB), Linz, Austria. |
| Short address (invited short communication) |
| “The role of tenofovir in the control (therapy and prevention) of HIV infection” (invited public lecture). |
| 29-30 November 2011 |
Discussions, EUVIRNA Supervisory Board, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands (host: Prof. Frank van Kuppeveld). |
| 22-23 November 2011 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| Lessons 21-25: Clinical case reports in antiviral chemotherapy: VZV, HSV, HPV, MCV, Orf, HPV, EBV, SIV, HBV, HBV. |
| 8-9 November 2011 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 12: Vitamins (A, B, C, D, E, …) (parts 1 and 2): structure, synthesis, mechanism of action, pathology associated with hypo- and hypervitaminoses. Case report 15. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| 25-26 October 2011 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h)at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 7: Biosynthesis and biological role of bile acids. Biosynthesis of cholesterol. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. Case report 6. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. Case report 7. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …). Case reports 8 and 9. |
| Lesson 11 (parts 1, 2, 3 and 4): Hormones (thyroid hormone, parathyroid hormone, insulin, glucagon, catecholamines, steroid hormones, pituitary gland hormones, hypothalamus hormones, gastrointestinal hormones: structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). Case reports 10-14. |
| 11-12 October 2011 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor |
| (Total: 7.5 h) at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. Case report 1. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). Case report 2. |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. Case report 3. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. Case report 4. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. Case report 5. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| August 2011 |
Henry Stewart Talks. The Biomedical & Life Sciences Collection. |
| Series: Antivirals, edited by E. De Clercq. |
| “Prospects of anti-HIV therapy and prophylaxis”. |
| 20-21 July 2011 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 14 July 2011 |
“A 40 year journey in the search for specific antiviral agents”, Department of Chemistry, University of Hull, United Kingdom (host: Prof. Dr. S. (Steve) J. Archibald, Department of Chemistry, University of Hull). |
| 24 May 2011 |
Commemoration of 25 Years of Crossing the Borders of East-West-Academic-Industrial-Valorisation. A special tribute to the collaboration between Erik De Clercq, Antonin Holý and John C. Martin, celebration held at the University of Leuven, Leuven, Belgium. |
| 16-17 May 2011 |
Scientific Advisory Board (SAB) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 5 May 2011 |
Antonin Holý Symposium: Chemistry Meets Biology, National Technical Library, Prague, Czech Republic. |
| Chairman of the Symposium (invited) (host: Zdenek Havlas, Director, IOCB, in the presence of HE Renilde Loeckx-Drozdiak, Belgian Ambassador to the Czech Republic). |
| 4 May 2011 |
Celebration of Holý Trinity, Průhonice Castle, Prague, Czech Republic. |
| “Holý Trinity” (invited lecture), in honor of Antonin Holý, Erik De Clercq and John C. Martin (host: Zdenek Havlas, Director, Institute of Organic Chemistry and Biochemistry (IOCB), Prague, Czech Republic) (in the presence of HE Renilde Loeckx-Drozdiak, Belgian Ambassador to the Czech Republic). |
| 7 April 2011 |
“A 40-year journey in search of selective antiviral chemotherapy”, School of Pharmacy, Fudan University,Shanghai, P.R. China (host: Prof. Dr. Fen-Er Chen, Fudan Department of Chemistry, Fudan University, Shanghai, P.R. China). |
| 17 March 2011 |
“The acyclic nucleoside phosphonates: the Holý Grail”, Centre de Recherche Public de la Santé (CRP-Santé), Centre Hospitalier de Luxembourg (CHL), Luxemburg. |
| 10-11 March 2011 |
Scientific Discussions, Scientific Council, Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCL), Woluwé, Brussels, Belgium. |
| 21-22 July 2010 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 15-16 June 2010 |
Scientific Advisory Board (SAB) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 1 June 2010 |
“The acyclic nucleoside phosphonates: a Holý Journey”, Institut für Anorganische Chemie, Johannes Kepler Universität (JKU), Linz, Austria (hosts: Prof. Dr. Nobert Müller and Prof. Dr. Günther Knör). |
| 20-21 March 2010 |
International Advisory Board (IAB) meeting of the IOCB (Institute of Organic Chemistry and Biochemistry), Academy of Sciences of the Czech Republic (host: Dr. Zdenek Havlas, Director, IOCB). |
| 22 February 2010 |
“The AMD3100 story: the path from an anti-HIV agent to a stem cell mobilizer”, Division of Infection & Immunity, Windeyer Building, University College of London (UCL) (host: Prof. Dr. A. Fassati). |
| 7 January 2010 |
Discovery of VireadTM and its therapeutic use, Gilead BeNeLux Meeting, Eindhoven, The Netherlands (host: Gilead BeNeLux). |
| 8 December 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Students’ examinations |
| 10-11 November 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| 3-4 November 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 11 (parts 1, 2, 3 and 4): Hormones (structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). |
| Lesson 12: Vitamins (A, B, C, D, E, …) (parts 1 and 2): structure, synthesis, mechanism of action, pathology associated with hypo- and hypervitaminoses. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| 27-28 October 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| Lesson 7: Biosynthesis and biological role of bile acids. Biosynthesis of cholesterol. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …). |
| 6-7 October 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. Host: Prof. Dr. Libor Grubhoffer, Dean Faculty of Science. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. |
| 28 September 2009 |
“Current developments on antiretrovirals: from chemistry to medicine”, Symposium on Development to Antiviral Chemotherapy: From Molecule to Medicine, Marmara University, Istanbul, Turkey (host: Prof. Dr. Ilkay Küçükgüzel and Prof. Dr. Sevim Rollas, Dean of the Pharmaceutical Faculty (Eczacilik Fakültesi)). |
| 16 September 2009 |
“Anti-HIV drug strategies”, University of Rijeka, Croatia (host: Prof. Dr. Mladen Mintas and Prof. Krešimir Pavelić, University of Rijeka, Croatia). |
| 15 September 2009 |
“Anti-HIV drug strategies”, Croatian Academy of Sciences and Arts, Zagreb, Croatia (host: Prof. Dr. Mladen Mintas, Professor ordinarius, University of Zagreb, Croatia). |
| 28-29 July 2009 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 3 July 2009 |
(Invited) Advisor (together with Prof. Dr. Myra McClure) to the Strategic Translation Award Application on “Novel Antiviral Agents that Target HIV-1 Replication in Cellular Reservoirs”, The Wellcome Trust, London, United Kingdom. |
| 23-24 June 2009 |
Scientific (Advisory) (S(A)B) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 5 June 2009 |
“Antiviral activity of acyclic nucleoside phosphonates (cidofovir, adefovir and tenofovir), Jihočeska Universita (University of South Bohemia), České Budějovice, Czech Republic (host: Prof. Dr. Libor Grubhoffer, Dean of the Faculty of Sciences). |
| 14 May 2009 |
“Discovery of the acyclic nucleoside phosphonates cidofovir, adefovir and tenofovir as antiviral drugs”, Seminars “New Strategies in Pharmaceutical Research”, Universität Wien, Pharmaziezentrum, Vienna, Austria (hosts: Dr. Irène Lagoja, Prof. Ernst Urban, Vice Head, and Prof. Christian Noe, Head of the Department of Medicinal Chemistry, University of Vienna). |
| 10-11 February 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. |
| Students’ examinations |
| 5-7 January 2009 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. |
| Lesson 13 (part 2): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, antifungal agents, nucleic acid synthesis inhibitors, tuberculostatics): mechanism of action (second part). |
| Lesson 14: Mechanisms of resistance development to antibiotics. Mechanism of transfer of resistance development (transformation, conjugation, transposition, transduction). |
| Lesson 15: Viral infections (symptoms) (part 1). DNA viruses. Viral infections (symptoms) (part 2). RNA viruses. |
| Lesson 16 : Antiviral agents (overview) for DNA viruses (part 1). Antiviral agents (overview) for RNA viruses (part 2). |
| Lesson 17: Current state of antiviral drugs in the treatment of AIDS (HIV infections). |
| Lesson 18: Treatment of varicella-zoster virus (VZV) infections, and herpes simplex virus (HSV) infections |
| Lesson 19: Acyclic nucleoside phosphonates: cidofovir, adefovir, tenofovir. |
| Lesson 20: The bicyclam AMD3100 story. |
| 2-3 December 2008 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. |
| Lesson 11: Hormones (structure, biosynthesis, functions, mechanism of action, regulation, catabolism, pathology). |
| Lesson 12: Vitamins (A, B, C, D, E, …): structure, synthesis, mechanism of action, pathology associated with hypo- or hypervitaminoses. |
| Lesson 13 (part 1): Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action (first part). |
| 18-19 November 2008 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| Lesson 7: Biosynthesis and biological role of bile acids. Biosynthesis of cholesterol. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotonine, …). |
| 4-5 November 2008 |
Course on “Biochemistry at the Service of Medicine”, as Visiting Professor at the Faculty of Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), jointly with Johannes Kepler Universität (Linz, Austria), Ceské Budĕjovice, Czech Republic. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. |
| 28 October 2008 |
Scientific Board of Directors Meeting, Inhibitex Inc., Washington Plaza, Washington DC, USA. |
| 22 September 2008 |
Second Generation HCV Advisory Board Meeting, Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, USA (meeting held in New York City, New York, USA) (host: Dr. Robert Kauffman, Senior Vice-President Clinical Development, and Meeting Moderator). |
| 12 September 2008 |
“Approches thérapeutiques antivirales” (Antiviral therapeutic approaches), Conférences sur la Virologie Fondamentale et Virologie Médicale et Moléculaire, Institut Pasteur, Paris, France (hosts: N. Tordo, J.-P. Vartanian and other leaders of this Course at the Pasteur Institute in Paris). |
| 29-30 July 2008 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 20 June 2008 |
“Acyclic nucleoside phosphonates for the treatment of HIV and HBV infections”, National Institutes of Health (NIH), Bethesda, Maryland, USA [host: Dr. Leonid Margolis, National Institute of Child Health and Human Development (NICHD)]. |
| 19 June 2008 |
Scientific Advisory Board Meeting, HHV-6 Foundation, Hyatt Regency, Baltimore, Maryland, USA. |
| 11 June 2008 |
“Current treatment regimens for HIV infections: role of the acyclic nucleoside phosphonates”, School of Pharmaceutical Sciences, Shandong University (Vice President: Lou Hongxiang, Professor of Natural Prodructs Chemistry) (host: Prof. Dr. Xinyong Liu, Vice Dean, Professor of Medicinal Chemistry, Director of Medicinal Chemistry Institute), Jinan, P.R. China. |
| 10 June 2008 |
“Current treatment regimens for HIV infections”, Department of Chemistry (host: Prof. Dr. Fen-Er Chen), Institute of Biomedical Sciences (host: Prof. Dr. Pengyuan Yang), and Shanghai Medical College (host: Prof. Dr. Yu-Mei Wen), Fudan University, Shanghai, P.R. China. |
| 19-20 May 2008 |
Scientific Advisory Board (SAB) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 2 April 2008 |
Lecture on “Acyclic nucleoside phosphonates in the scope of the current treatment regimes for the treatment of HIV and HBV infections (host: Prof. Dr. Binghe Wang, Eminent Scholar of Georgia Research Alliance, Georgia State University, Atlanta, Georgia 30302, USA). |
| 1-2 April 2008 |
Visit to and Discussions with several members of the Departments of Chemistry and Biology, Georgia State University, Atlanta, Georgia 30302, USA. |
| 1 April 2008 |
Visit to Georgia Research Alliance (host: C. Michael Cassidy, President and CEO), The Hurt Building, 50 Hurt Plaza, Atlanta, Georgia 30303, USA. |
| 31 March 2008 |
Scientific Board of Directors Meeting, Inhibitex Inc., 9005 Westside Parkway, Alpharetta, Atlanta, Georgia 30004, USA. |
| 14 February 2008 |
The Fifth Annual D. Lorne Tyrrell Lectureship in Infection and Immunity “New perspectives for the treatment of virus (i.e. HIV, HBV and HCV) infections”, The University of Alberta, Edmonton, Alberta, Canada (host: Prof. H. Ostergaard, Chair Immunology Network). |
| 13 February 2008 |
“The antiviral and antitumor activities of acyclic nucleoside phosphonates”, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (host: Prof. Dr. Jonathan Dimmock). |
| 12 December 2007 |
Students’ examinations. Course on “Biochemistry at the Service of Medicine”, Faculty of Biological Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), Ceské Bodĕjovice, Czech Republic. |
| 11 December 2007 |
Course on “Biochemistry at the Service of Medicine”, Faculty of Biological Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), Ceské Budĕjovice, Czech Republic. |
| Lesson 12: Vitamins (A, B, C, D, E, …): structure, synthesis, mechanism of action, pathology associated with hypo- or hypervitaminoses. |
| Lesson 13: Antibiotics (penicillins, vancomycin, protein synthesis inhibitors, nucleic acid synthesis inhibitors, tuberculostatics): mechanisms of action and mechanisms of resistance development and resistance transmission. |
| Lesson 14: Clinical manifestations of viral diseases (DNA viruses, RNA viruses and retroviruses). |
| Lesson 15: Current treatment options for human immunodeficiency virus (HIV) infections. |
| Lesson 16: The acyclic nucleoside phosphonates in the scope of HIV, HBV and other virus infections. |
| Lesson 17: The path to drug discovery, as illustrated by the AMD3100 story. |
| 20-21 November 2007 |
Course on “Biochemistry at the Service of Medicine”, Faculty of Biological Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), Ceské Budĕjovice, Czech Republic. |
| Lesson 7: Biosynthesis and biological role of bile acids. Biosynthesis of cholesterol. |
| Lesson 8: Gastrointestinal system: absorbance and digestion of proteins, carbohydrates and triglycerides. |
| Lesson 9: Important cycles in intermediary metabolism: citric acid cycle, γ-glutamyl transpeptide cycle (γ-GT), urea cycle, γ-aminobutyric acid (GABA) cycle. |
| Lesson 10: Neurotransmitters (acetylcholine, dopamine, noradrenaline, serotine, …). |
| Lesson 11: Hormones (structure, biosynthesis, functions, mechanism of action, regulation, katabolism, pathology). |
| 26 October 2007 |
Examination Thèse de doctorat de l’Université Pierre et Marie Curie: Nouveaux inhibiteurs de la dimérisation de la protéase du VIH-1: relations structure-activité, preuves mécanistiques et effets sur des protéases mutées (Ludovic Bannwarth), Université Pierre et Marie Curie, Université Paris 6, Paris, France (host: Prof. Dr. Michèle Reboud-Ravaux). |
| 25 October 2007 |
“Les nucléosides acycliques phosphonylées en vue des nouvelles stratégies pour le traitement du SIDA” (The acyclic nucleoside phosphonates in the scope of the treatment of human immunodeficiency virus (HIV) and other virus infections), Institut Jacque Monod, Centre National de la Recherche Scientifique, Université Pierre & Marie Curie, Université Paris 6, Paris, France (host: Prof. Dr. Michèle Reboud-Ravaux, Enzymologie Moléculaire et Fonctionnelle, FRE2852-CNRS)? |
| 16-17 October 2007 |
Course on “Biochemistry at the Service of Medicine”, Faculty of Biological Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), Ceské Budĕjovice, Czech Republic. |
| Lesson 4: Biosynthesis of heme, Hemoglobine, Porphyrias (porphyrinurias), Hemoglobinopathies, Sickle cell anemia. |
| Lesson 5: Glycolysis, Pentose phosphate shunt pathway, Hemolytic anemias. |
| Lesson 6: Degradation of heme, Biliverdin, Bilirubin, Direct and indirect bilirubin, Urobiline, Hepatitis, Hemolytic icterus, Obstructive icterus, Liver function tests. |
| 8-10 October 2007 |
Participation in Academic Delegation accompanying their Majesties The King and the Queen of the Belgians at the occasion of the State Visit to Ireland (Dublin and Shannon). |
| 2-3 October 2007 |
Course on “Biochemistry at the Service of Medicine”, Faculty of Biological Sciences, The University of South Bohemia (Jihočeská Universita Ceských Budĕjovicich), Ceské Budĕjovice, Czech Republic. |
| Lesson 1: Nucleosides versus nucleotides – De novo biosynthesis of purine mononucleotides – IMP dehydrogenase – IMP dehydrogenase inhibitors (i.e. ribavirin) – Capping of viral mRNA – Methyltransferase – S-adenosylmethionine (SAM) – S-adenosylhomocysteine (SAH) – SAH hydrolase inhibitors. |
| Lesson 2: De novo biosynthesis of pyrimidine mononucleotides – Orotic acid aciduria – Thymidylate synthase – Folic acid (Folate) – Folate metabolites (N5,N10-methylene-FH4, N5N10-methenyl-FH4 – N10-formyl-FH4) – Folate antagonists [i.e. amethopterine (Methotrexate)] – Creation of a carbon-carbon bond (dUMP → dTMP). |
| Lesson 3: Salvage reactions in the biosynthesis of purine and pyrimidine mononucleotides – Lesh-Nyhan syndrome – Catabolism of purine mononucleotides – Uric acid – Gout – Allopurinol (treatment of gout) – Catabolism of pyrimidine mononucleotides – Dihydropyrimidine dehydrogenase (DPD) – 5-Fluorouracil. |
| 19 September 2007 |
Directors’ Board Meeting Fermavir, New York, New York, USA (host: Dr. Geoffrey Henson, Chief Executive Officer, Fermavir). |
| 17-18 July 2007 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, Chief Executive Officer and N. Bischofberger, Chief Scientific Officer, Gilead Sciences). |
| 11-12 July 2007 |
Scientific (Advisory) (S(A)B) Meeting, Centre for Drug Design and Discovery (CD3), Katholieke Universiteit Leuven (K.U.Leuven), Belgium (host: Leuven Research and Development (LRD)). |
| 22 June 2007 |
Students’ examinations, Course on “Molecular Mechanisms of Antibiotics and Antiviral Agents”, Department of Genetics and Microbiology, Faculty of Sciences, Charles University, Vinična, Prague, Czech Republic (host: Prof. Dr. Jitka Forstová, Department of Genetics and Microbiology). |
| 20 June 2007 |
Lecture on “The acyclic nucleoside phosphonates: the Prague-Leuven connection: how it started (in 1976) and evolved”, Faculty of Biological Sciences, University of South Bohemia, České Budějovice, Czech Republic (host: Prof. RNDr. Libor Grubhoffer, Dean of the Faculty of Biological Sciences). |
| 31 May-1 June 2007 |
Course on Antibacterial and Antiviral Chemotherapy, Institute of Genetics and Microbiology (Katedra Genetiky a Mikrobiologie), Faculty of Sciences, Charles University, Prague, Czech Republic. |
| “Specific antiviral drugs: Anti-influenzavirus agents”. |
| “Specific antiviral drugs: Anti-HBV agents”. |
| “Specific antiviral drugs: Anti-HCV agents. “. |
| “Specific antiviral drugs: Anti-poxvirus agents”. |
| “Specific antiviral drugs: Anti-RSV agents”. |
| “Epilogue: The AMD-3100 story: A paradigm for drug discovery”. |
| 26 May 2007 |
“Pandemic influenza and antivirals”. Lecture delivered at the Fourth Giornata Siciliana di Approfondimento Infettivologico (4th Sicilian Day on Infectious Diseases), Museo Diocesano, Piazza Duomo, Catania, Sicilia, Italy (host: Senola di Specializzazione Infettive, Universita di Catania, Sicilia). |
| 17-18 May 2007 |
Course on Antibacterial and Antiviral Chemotherapy, Charles University (Faculty of Medicine and Faculty of Sciences) and Czech Academy of Sciences (Institute of Molecular Genetics), Prague, Czech Republic. |
| “Antiviral strategies (general)”. |
| “Licensed antiviral drugs: Overview )”. |
| “Licensed anti-HIV drugs: Overview”. |
| “Specific antiviral drugs: Brivudin for treatment of VZV infections)”. |
| “Specific antiviral drugs: Acyclic nucleoside phosphonates (Cidofovir, Adefovir, Tenofovir): The phosphonate bridge”. |
| 11 May 2007 |
Scientific Advisory Board (SAB) meeting, Z-Cube (Zambon’s Corporate Venture Company), Grand Hotel Eden, Lugano, Paradiso, Switzerland (host: Dr. Claudio Semeraro, Chief Executive Officer (CEO) of Z-Cube). |
| 4 May 2007 |
Scientific discussions on development of antiviral agents, Gilead Sciences, Foster City, California, USA (hosts: Dr. J.C. Martin, Chief Executive Officer (CEO) and Executive President, and Dr. N. Bischofberger, Chief Scientific Officer and Executive Vice President, Gilead Sciences). |
| 25-26 April 2007 |
Course on Antibacterial and Antiviral Chemotherapy, Charles University (Faculty of Medicine and Faculty of Sciences) and Czech Academy of Sciences (Institute of Molecular Genetics), Prague, Czech Republic. |
| “Clinical symptoms caused by viruses (part I)”. |
| “Clinical symptoms caused by viruses (part II) “. |
| “Antivirals active against DNA viruses/retroviruses (preclinical/clinical/ licensed) Part I (overview)”. |
| “Antivirals active against RNA viruses (preclinical/clinical/licensed) |
| Part II (overview)”. |
| 25 April 2007 |
“The bicyclam AMD3100 story: the route of discovery of a stem cell mobilizer”, Univerzita Karlova Praze, 2. Lékařská Fakulta Motol, Prague, Czech Republic (host: Prof. Dr. Ondrey Hrušák, Dean of the Second Medical Faculty, Charles University, Prague). |
| 19-20 April 2007 |
Course on Antibacterial and Antiviral Chemotherapy, Charles University (Faculty of Medicine and Faculty of Sciences) and Czech Academy of Sciences (Institute of Organic Chemistry and Biochemistry), Prague, Czech Republic. |
| “Introduction to eubacteria”. |
| “Antibiotics interacting with biosynthesis of peptidoglycans: β-lactam antibiotics (penicillins, vancomycin, …)”. |
| “Antibiotics inhibiting protein synthesis: aminoglycosides, … macrolides”. |
| “Antibiotics interfering with nucleic acid biosynthesis: quinolones, sulfonamides, rifampicin”. |
| “Antibiotics: mechanisms of development of resistance”. |
| “Antibiotics: mechanisms of transmission of resistance”. |
| “Antibiotics: tuberculostatics”. |
| 23 March 2007 |
Examination viva PhD thesis entitled “Molecular and biochemical studies of feline herpesvirus-1 thymidine kinase and its role in the development of effective antiviral compounds” by Islam Tohamy Mohammad, University of Cambridge, United Kingdom. |
| 8 March 2007 |
“Discovery and development of specific antiviral agents”. Lecture presented at the occasion on being awarded the degree of doctor honoris causa of Charles University in Prague (Universitas Carolina Pragensis), Czech Republic. |
| 28 September 2006 |
Z-Cube (Zambon Group) Scientific Advisory Board Meeting, Grand Hotel Eden, Lugano, Switzerland (host: Dr. Claudio Semeraro, Executive Director Z-Cube). |
| 1 September 2006 |
“At Professor Antonin Holý’s Memorable 70th birtday, 30 years of Holý nomics”, Prague, Czech Republic. Lecture delivered at the occasion of the celebration of the 70th birthday of Antonin Holý (hosts: Prof. Vaclar Pačes,, President of Czech Academy of Sciences, and Prof. Zdenek Havlas, Director of the Institute of Organic Chemistry and Biochemistry). |
| 26 July 2006 |
“The (first) years of wisdom”, Board Dinner Lecture delivered at the Gilead Sciences Board of Directors, Scientific Advisors and Operating Group, Foster City, California, USA. |
| 25-26 July 2006 |
Scientific Advisory Board (SAB) Meeting, Gilead Sciences, Foster City, California, USA (hosts: J.C. Martin, President and Chief Executive Officer, N. Bischofberger, Executive Vice President Research and Development, and W.A. Lee, Senior Vice-President Research). |
| 14 July 2006 |
“Bridging chemistry to HIV, HBV, HCV, papilloma-, adeno-, herpes-, and poxvirus infections: the phosphonate bridge”. Theoretical Institutes of Faculty of Medicine, Palacky University, Olomouc, Czech Republic (hosts: Prof. A. Holý and Prof. Marian Hajduch, head of Laboratory of Experimental Medicine, Department of Pediatrics, Faculty of Medicine. |
| 13 July 2006 |
Establishment of New Academic Research Center, Gilead Sciences and Institute of Organic Chemistry and Biochemistry (IOCB), in Prague, Czech Republic. Donation by Gilead in honor of Dr. Antonin Holý (host: Prof. Vaclav Pačes, President, Academy of Sciences, Czech Republic). |
| 16 March 2006 |
Scientific Advisory Board (SAB) Meeting, Fermavir Pharmaceuticals Inc., New York, New York, USA (host: Dr. G.W. Henson, Chief Executive Officer, Fermavir Pharmaceutical Inc.). |
| 3 February 2006 |
Antiviral agents against avian influenza virus H5N1 (Agenti antivirali contro il virus H5N1), Fondazione Bonino-Pulejo (Messina), Universitá degli Studi di Messina, Sicily, Italy [hosts: Prof. Dr. Giovanni Romeo (Universitá di Messina) and Dr. Piero Orteca (Fondazione Bonino-Pulejo, Messina)]. |
| 13-14 December 2005 |
Science meeting prior to Meeting of the Board of Directors, FermaVir, New York, New York, USA (host: Dr. Geoffrey Henson, Chief Executive Officer, FermaVir Pharmaceuticals). |
| 12 December 2005 |
4AZA Bioscience Scientific Advisory Board (SAB) Meeting, Berkenhof Bierbeek, Belgium (host: Dr. Mark de Boer, Chief Executive Officer, 4AZA Bioscience). |
| 16 November 2005 |
Scientific discussions collaborations between Rega Institute (K.U.Leuven) and Institute of Organic Chemistry and Biochemistry (IOCB), Czech Academy of Sciences, Praha, Czech Republic (hosts: Prof. A. Holý, Prof. Z. Havlas, Director IOCB, and Prof. Václav Pačes, President of Czech Academy of Sciences). |
| 11 November 2005 |
“Antiviral drugs and antiviral strategies”, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, P.R. China (hosts: Prof. Wu Song, Deputy Director, Institute of Materia Medica, and Prof. Du Guanhua, President, Institute of Materia Medica, Beijing, P.R. China). |
| 10 November 2005 |
“Antiviral drugs for the treatment of hepatitis B and C”, Shandong University, Jinan, P.C. China (hosts: Prof. Xinyong Liu, Dean of the Department of Organic Chemistry, and Prof. Yun Zhang, Vice-President, Shandong University, Jinan, P.R. China). |
| 9 November 2005 |
”Antiviral drugs for the treatment of HIV infections (AIDS)”, Shandong University, Jinan, P.R. China (hosts: Prof. Xinyong Liu, Dean of the Department of Organic Chemistry, and Prof. Yun Zhang, Vice-President, Shandong University, Jinan, P.R. China). |
| 9 November 2005 |
“Antiviral drugs and antiviral strategies”, Shandong University, Jinan, P.R. China (hosts: Prof. Xinyong Liu, Dean of the Department of Organic Chemistry, and Prof. Yun Zhang, Vice-President, Shandong University, Jinan, P.R. China). |
| 26 October 2005 |
Z-Cube (Zambon Group) Scientific Advisory Board Meeting, Grand Hotel Eden, Lugano, Switzerland (Chairman: Prof. Dr. Renato Dulbecco; host: Dr. Claudio Semeraro). |
| 9 September 2005 |
BioVitas Scientific Advisory Board (SAB) Meeting, Hotel D’Inghilterra, Rome, Italy (host: Gabriele M. Cerrone, Chairman BioVitas Capital, Rome, Italy, and New York, USA). |
| 26-27 July 2005 |
Gilead Scientific Advisory Board Meeting, Gilead, Foster City, California, USA. Discussion of Research and Development Programs (hosts: N. Bischofberger, Executive Vice President Research & Development; and Dr. W.A. Lee, Senior Vice President Research). |
| 11 July 2005 |
Scientific discussions, Scientific Advisory Board Meeting, Fermavir Research, Inc., New York, New York, USA (host: Dr. G. Henson, Chief Executive Officer, Fermavir Research). |
| 5 May 2005 |
Z-Cube (Zambon Group) Scientific Advisory Board Meeting, Grand Hotel Eden, Lugano, Switzerland (Chairman: Prof. Dr. Renato Dulbecco; host: Dr. Claudio Semeraro). |
| 22 November 2004 |
“The acyclic nucleoside phosphonates (ANPs): past, present and future”, Institute of Organic Chemistry and Biochemistry (IOCB), Academy of Sciences of the Czech Republic, Prague, Czech Republic (host: Prof. Dr. Anthonin Holý, Former Director, IOCB). |
| 20-21 November 2004 |
Discussions, Advisory Board Meeting, Institute of Organic Chemistry and Biochemistry (IOCB), Academy of Sciences of the Czech Republic, Prague, Czech Republic (host: Dr. Zdenek Havlas, Director, IOCB). |
| 18 November 2004 |
BioVitas Scientific Advisory Board (SAB) Meeting, Hotel Principe di Savoia, Milan, Italy (host: Gabriele M. Cerrone, Chairman BioVitas Capital, New York, USA). |
| 6 November 2004 |
Participant in the capacity of Editor of Antiviral Research, Elsevier Editors’ Conference on “Partnerships for Quality Science”, Elsevier, Valparaiso Palace Hotel, Majorca, Spain (Conference Chairman: Prof. Peter van der Vliet, Editor-in-Chief of Biochimica Biophysica Acta). |
| 20 October 2004 |
Lecture and discussions on “Antivirals and antiviral strategies”, Clavis Pharma, Oslo, Norway (hosts: Dr. Finn Myhren, Dr. Marit Liland Sandvold and Dr. Tom Pike, Chief Executive Officer). |
| 13 October 2004 |
Z-Cube (Zambon Group) Scientific Advisory Board Meeting, Grand Hotel Eden, Lugano, Switzerland (Chairman: Prof. Dr. Renato Dulbecco; host: Dr. Claudio Semeraro). |
| 27 August 2004 |
“Interferon (inducers): a never-ending story”, lecture delivered at the occasion of the Festschrift honoring Thomas C. Merigan, Bridging Generations Toward an Understanding of Infectious Disease Pathogenesis, Clark Center for Biomedical Engineering and Sciences, Stanford University School of Medicine, Stanford, California, USA. |
| 26 August 2004 |
Discussions on the development of new antiviral agents, Anacor Pharmaceuticals, Palo Alto, California, USA (hosts: Dr. Jake Plattner, Vice-President, and Dr. David Perry, Chief Executive Officer). |
| 27-28 July 2004 |
Gilead Scientific Advisory Board Meeting, Gilead, Foster City, California, USA. Discussion of Research and Development Programs (hosts: J.C. Martin, President and Chief Executive Officer; N. Bischofberger, Executive Vice President Research & Development; William Lee, Senior Vice President Research). |
| 22 July 2004 |
AnorMED Inc. Annual Scientific Advisory Board Meeting, Langley, British Columbia, Canada (hosts: M.J. Abrams, President, and Dr. G.J. Bridger, Vice President Research, AnorMED Inc.). |
| 16 June 2004 |
Discussion of scientific research projects, Z-Cube Scientific Advisory Board meeting, Grand Hotel Eden, Lugano, Switzerland [hosts: Dr. Claudio Semeraro, Executive Director and Dr. Roberto Rettani, President, Z-Cube (Zambon Group)] (Chairman of the meeting: Prof. Dr. Renato Dulbecco). |
| 15 December 2003 |
“New anti-HIV drug developments”, Second Workshop on Antiviral Modified Nucleosides, Auditorium della Gazzetta del Sud, Messina, Italy (hosts: Prof. G. Romeo, Universita degli Studi di Messina and Dott. Piero Ortega, Fondazione Bonino-Pulejo). |
| 12 December 2003 |
Attendance of Sir Thomas Smith’s Feast, Queens College, Cambridge, United Kingdom (hosts: Dr. Hugh Field and Dr. Murray Milgate, Fellows of Queens College). |
| 3 November 2003 |
Discussant, Novartis Foundation Discussion Meeting on “Drugs for Developing World Diseases: Translating New Molecular Targets into Candidates for Development”, Novartis Foundation, London, United Kingdom (Chairman: Prof. Trevor Jones, Association of the British Pharmaceutical Industry). |
| 28-31 July 2003 |
Scientific Advisory Board Meeting, discussions on the development of antiviral agents, Gilead, Foster City, California, USA (host: Dr. J.A. Martin, Chief Executive Officer and President, and Dr. N. Bischofberger, Executive Vice President, Research and Development). |
| 24 July 2003 |
Discussions on the development of bicyclam derivatives as clinically effective drugs for multiple indications, AnorMED Inc. Annual Scientific Advisory Board Meeting, Langley, British Columbia, Canada (host: M.J. Abrams, President, and Dr. G.J. Bridger, Vice President Research, AnorMED Inc.). |
| 10 July 2003 |
Discussion on “European Vigilance Network for the Management of Antiviral Drug Resistance (viRgil)”, Network of Excellence, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France (host: Prof. Fabien Zoulim, INSERM-Lyon). |
| 18-19 June 2003 |
“Current status of antivirals development”, presented at a special brainstorming meeting on “Smallpox: Transforming Biological Information into New Therapies” at the National Academies of the United States, Washington DC, USA (host: Dr. Bruce Alberts, President of the National Academy of Sciences, USA). |
| 29 May 2003 |
Anti-HIV (AIDS) therapies: targets and approaches, Dottorato di Ricerca in Scienze Farmaceutiche, Facoltà di Farmacia, Università degli Studi di Catania, Catania, Sicily, Italy (host: Prof. Dr. Giuseppe Ronsisvalle). |
| 28 May 2003 |
Anti-HIV (AIDS) therapies: targets and approaches, Dottorato di Ricerca in Scienze Farmaceutiche, Dipartimento Farmaco-Chimico Facoltà di Farmacia, Università degli Studi di Messina, Messina, Sicily, Italy (host: Prof. Dr. Alba Chimirri). |
| 27 May 2003 |
Anti-HIV (AIDS) therapies: targets and approaches, Dottorato di Ricerca in Scienze Farmaceutiche, Dipartimento Farmacochimico Tossicologico e Biologico, Università degli Studi di Palermo, Palermo, Sicily, Italy (hosts: Prof. Dr. Girolamo Cirrincione and Prof. Dr. Anna Maria Almerico). |
| 27 August 2002 |
Expert Advice on “Future directions in HIV therapy”, UBS Warburg, London, UK (host: Dr. Andrew Kocen, European Pharmaceutical Research, UBS Warburg). |
| 26 July 2002 |
Discussions on the development of bicyclam derivatives as clinically effective drugs for multiple indications, AnorMED Inc. Annual Scientific Advisory Board Meeting, Langley, British Columbia, Canada (host: M.J. Abrams, President and Chief Executive Officer of AnorMED Inc.). |
| 24-25 July 2002 |
Discussions on the development of antiviral drugs, Annual Scientific Advisory Board Meeting, Gilead Sciences, Inc., Foster City, California, USA (host: Dr. John C. Martin, President and Chief Executive Officer, and Dr. Norbert Bischofberger, Executive Vice President, Gilead Sciences, Inc.) |
| 6 February 2002 |
Discussion on candidate anti-HIV microbicides. NIH (National Institutes of Health) FY 2004 Plan for HIV-Related Research, Microbicides Research Area of Emphasis, Crystal City Hilton, Virginia, USA (chair: Dr. Fulvia di Marzo Veronese, Office of AIDS Research, Office of the Director, National Institutes of Health). |
| 5-6 December 2001 |
Program Committee Meeting of the 15th International Conference on Antiviral Research (Prague, Czech Republic, 17-21 March 2002), Hyatt Regency Reston, Virginia, USA. |
| 3 December 2001 |
Discussions on the potential usefulness of bicyclic (furopyrimidine) nucleoside analogues (BCNAs) in the treatment of varicella-zoster virus (VZV) infections, Berlin-Chemie AG (Menarini), Berlin, Germany (host: Dr. B. Stubinski, Berlin-Chemie). |
| 15 November 2001 |
Charting Pathways to Future Infectious Disease Treatment Therapies, Infectious Disease Expert Summit Meeting, Novartis, O’Hare, Chicago, Illinois, USA (host: Dr. Stephan A. Billstein, Executive Director, Novartis Pharmaceutical Corporation). |
| 27 July 2001 |
Scientific Advisory Board Meeting, AnorMED (Langley, British Columbia, Canada), held at Semiahmoo Resort, Blaine, Washington (USA) [hosts: AnorMED executive team (Dr. M. Abrams, Dr. G. Henson, Dr. G. Bridger)]. |
| 18-19 July 2001 |
Annual Scientific Advisors (POW-HOW) Meeting, Gilead Sciences, Foster City, California, USA (hosts: John C. Martin, Chief Executive Officer, and Norbert Bischofberger, Senior Vice President). |
| 19-20 June 2001 |
Introductory presentations on antivirals against herpes- and hepatitisviruses and discussions on antivirals (against herpesvirus, respiratory viruses, human immunodeficiency virus, hepatitis B virus and hepatitis C virus). |
| Antiviral Meeting to evaluate current and future trends in viral diseases, AstraZeneca, Shrigley Park, Near Macclesfield, Cheshire, United Kingdom (host: Dr. Keith Williams, Global Product Director, AstraZeneca). |
| 29 April 2001 |
Research on antiviral therapy, Infectious Disease Therapeutic Area (IDTA), Antiviral Preclinical Research Advisory Meeting, Novartis, Vienna, Austria (host: Dr. Neil S. Ryder, Programme Head Novartis Forschungsinstitut GmbH). |
| 22 March 2001 |
“Recent developments in anti-HIV chemotherapy”, Medical Lecture Series, sponsored jointly by the Department of Internal Medicine and the Department of Chemistry, University of Iowa, Iowa City, Iowa, USA (host: Prof. Dr. Vasu Nair, University of Iowa Foundation Distinguished Professor). |
| 5 February 2001 |
“New developments in the chemotherapy of HIV infections”, AIDS Research Center, National Institute of Infectious Diseases, Toyama, Shinjuku-ku, Tokyo, Japan (host: Prof. Dr. Yoshiyuki Nagai, Director, AIDS Research Center). |
| 4 February 2001 |
“The dawn of antiviral chemotherapy: the Leuven-Fukushima connection”, Ceremonial meeting in honor of Professor Shiro Shigeta at his election to President of Fukushima Medical University, Fukushima, Japan (hosts: Prof. M. Baba, Kagoshima University; Prof. M. Ito, Yamanishi University; and Prof. K. Takahashi, Fukushima Medical College). |
| 3 February 2001 |
“New developments in the chemotherapy of HIV infections and AIDS”, Chiba Institute of Technology, Department of Industrial Chemistry, Chiba, Japan (host: Prof. Dr. Hiroshi Takaku). |
| 14 December 2000 |
Program Committee Meeting, planning of the 14th International Conference on Antiviral Research, Reston, Virginia, USA, to be held on 8-12 April 2001, Seattle, Washington, USA. |
| 14 December 2000 |
Scientific discussions on antiviral research, ISAR (International Society for Antiviral Research) Leadership Retreat, Reston, Virginia, USA (host: Leaders of the International Society for Antiviral Research). |
| 6-9 November 2000 |
Northern Arizona University (NAU), Department of Chemistry, Flagstaff, Arizona, USA. |
| Burroughs Wellcome Visiting Professor in the Microbiological Sciences, Burroughs Wellcome Foundation, administered by the American Society of Microbiology. |
| 6 November 2000“Highlights in development of antiviral agents”, CHM 152 class (Prof. Dr. H. Gunderson) presentation, Room 224, Chemistry Building. |
| “Antiviral agents: from chemistry to biology and medicine”, CHM 235 (Prof. Dr. E. Civitello) presentation, Room 225, Chemistry Building. |
| Minicourse # 1 “The chemotherapy of herpes virus infections” (Prof.Dr. P.F. Torrence), Room 130, Biology-Biochemistry Building. |
| 7 November 2000“Antiviral activity of thymidine analogues: brivudin, stavudine”, CHM 235 (Prof. Dr. J. MacDonald) presentation, Room 130, Biology-Biochemistry Building. |
| “Antiviral activity of acyclic nucleoside phosphonates”, CHM 151 (Prof. Dr. J. Wettaw) presentation, Room 225, Chemistry Building. |
| “Discovery of NNRTIs (non-nucleoside reverse transcriptase inhibitors)” as anti-HIV agents, CHM 151 (Prof. Dr. J. Wettaw) presentation, Room 225, Chemistry Building. |
| “Discovery of bicyclams as anti-HIV agents acting through blocking of CXCR4, the co-receptor for HIV entry into cells”, CHM 151 (Prof. Dr. W. Hildebrandt) presentation, Room 225, Chemistry Building. |
| Minicourse # 2A “The chemotherapy of influenza virus infection” (Prof. Dr. P.F. Torrence), Room 130, Biology-Biochemistry Building. |
| Minicourse # 2B “The chemotherapy of hepatitis B infection” (Prof. Dr. P.F. Torrence), Room 130, Biology-Biochemistry Building. |
| 8 November 2000“Combined gene therapy/chemotherapy for treatment of cancer” (Dr. D. Stearns), Room 106 |
| “Bromovinyldeoxyuridine in the treatment of HSV-1 and VZV infections”, CHM 152 (Dr. C. Hartzell), Room 224, Chemistry Building. |
| “Nucleoside and non-nucleoside analogues as anti-HIV agents”, CHM 151 (Dr. B. Cruickshank), Room 123, Liberal Arts Building (IITV course). |
| “Reverse transcriptase as target for anti-HIV agents”, CHM 151 (Dr. B. Cruickshank), Room 130, Biology-Biochemistry Building. |
| “Thymidylate synthetase as target for antitumor agents”, CHM 238 (Prof. Dr. P.F. Torrence), Room 224, Chemistry Building. |
| Minicourse # 3 “Molecular targets for chemotherapy of human immunodeficiency virus (HIV) infection” (Prof. Dr. P.F. Torrence). |
| Lecture s“Chemotherapy of human immunodeficiency virus (HIV) infection” (Prof. Dr. P.F. Torrence), Room 130, Biology-Biochemistry Building. |
| 9 November 2000Seminar “Acyclic nucleoside phosphonates as antiviral and antitumor agents” (Prof. Dr. P.F. Torrence), Room 130, Biology-Biochemistry Building. |
| 23 October 2000 |
“The history of Brivudin”, Brivudin Meeting, Berlin-Chemie, Menarini Group (hosts: Mr. H. Nelde, Prof. A. Giachetti, Dr. B. Stubinski, Berlin-Chemie AG). |
| 21 September 2000 |
“A crusade for drugs to conquer viruses: a personal reflection”, at the occasion of the proclamation of doctor honoris in Pharmacy, University of Ferrary, Italy (hosts: Il Rettore, Prof. F. Conconi, Il Preside de Facolta, Prof. J.P. Pollini, and Professors S. Manfredini and P.G. Baraldi). |
| 8 September 2000 |
Discussions on the development of HCV (hepatitis C virus) and HIV integrase inhibitors, Gilead Sciences, Foster City, California, USA (hosts: Dr. Max Hensley, Vice President for Intellectual Property and Dr. Bill Lee, Vice President of Research and Pharmaceutical Development). |
| 27 July 2000 |
Discussions, Annual Scientific Advisory Board Meeting, AnorMED Inc., Langley, British Columbia, Canada (host: Dr. M. Abrams, President and Chief Executive Officer, AnorMED). |
| 19-20 July 2000 |
Discussions on the development of antivirals, anti-cancer agents and anti-infectives, The Annual Grand Pow Wow meeting of Gilead Sciences, Foster City, California, USA (host: Dr. N. Bischofberger, Senior Vice-President Research, Gilead Sciences). |
| 19 April 2000 |
Discussions on in vitro and in vivo models for assessing antiviral activity of novel fatty acid conjugates, Protarga, Inc., Conshohocken, Pennsylvania, USA (host: Dr. Charles Swindell, Senior Vice President, Research & Development, Protarga). |
| 14 April 2000 |
Foreign Jury Member, Public Thesis Defense of Wilco Keulen “Evolution of drug-resistant HIV-1 variants”, University of Utrecht [Universitair Medisch Centrum (UMC)], Utrecht, The Netherlands (hosts: Prof. J. Verhoef, Dr. C.A.B. Boucher, Dr. B. Berkhout, promoters). |
| 6-7 January 2000 |
Program Committee Meeting, planning of the 13th International Conference on Antiviral Research, Baltimore, Maryland, USA, to be held on 16-21 April 2000, Baltimore, Maryland, USA. |
| 13 December 1999 |
Discussions on the preclinical and early clinical development of anti-HIV agents, AIDS ReSearch Alliance, West Hollywood, California, USA (hosts: Dr. Andrew Korotzer, Director of Scientific Communications, Dr. Stephen J. Brown, Director of Clinical Research, and Gregory S. Britt, Chief Executive Officer, AIDS ReSearch Alliance). |
| 10 December 1999 |
Informal Scientific Advisory Board meeting, Triangle Pharmaceuticals (Durham, NC), Kapalua, Maui, Hawaii, USA (hosts: Dr. P.A. Furman, Vice President Research and Dr. D.W. Barry, Chairman and Chief Executive Officer, Triangle Pharmaceuticals). |
| 15-17 November 1999 |
Scientific Advisory Council Meeting, Abbott Laboratories, Abbott Park, Illinois, USA (host: Dr. Daniel W. Norbeck, Vice-President, Pharmaceutical Discovery, Abbott Laboratories). |
| 5 November 1999 |
“Antiviral Drug Strategies”, Plenary Lecture presented at the Consejo Superior de Investigaciones Científicas at the occasion of the 25th Anniversary of the Instituto de Química Médica, Madrid, Spain (hosts: Dra. Ma T. Garcia López, Directora del Instituto de Química Médica, and Dr. César Nombela Cano, Presidente del Consejo Superior de Investigaciones Científicas). |
| 29 July 1999 |
Scientific Advisory Board Meeting, AnorMED, Langley, British Columbia, Canada (host: Dr. Michael Abrams, President and Chief Executive Officer, AnorMED). |
| 21, 22 July 1999 |
Annual Scientific Pow Wow meeting, Gilead Sciences, Foster City, California, USA (host: Dr. N. Bischofberger, Senior Vice-President Research, Gilead Sciences). |
| 13 July 1999 |
Discussions on antiviral potential of iminosugars (i.e. N-nonyl-deoxy-nojirimycin), for the treatment of HBV and HCV infections, Synergy Pharmaceuticals, Inc./Oxford Glycobiology Institute, Oxford, United Kingdom (host: Prof. Dr. R.A. Dwek, Director, Oxford Glycobiology Institute). |
| 3 July 1999 |
Brivudin Expert Meeting, Discussion on the development of brivudin (BVDU) as antiviral drug for the treatment of herpes zoster in immunocompetent individuals, Berlin-Chemie, Menarini, Rome, Italy (host: Dr. R. Brinkman, Brivudin-Team, Berlin-Chemie). |
| 22 June 1999 |
Scientific Advisory Board Meeting, Triangle Pharmaceuticals, meeting held at the Rancho Bernardo Inn, San Diego, California, USA (host: Dr. Phillip A. Furman, Chief Scientific Officer, Triangle Pharmaceuticals). |
| 21 June 1999 |
“New perspectives for the treatment of HIV infections”, Specialty Laboratories, Santa Monica, Los Angeles, California, USA (host: Dr. James B. Peter, Chairman of Specialty Laboratories). |
| 25-27 May 1999 |
Pharmaceutical Discovery Scientific Advisory Council Meeting, Abbott Laboratories, Abbott Park, Illinois, USA (hosts: Dr. Daniel W. Norbeck, Vice President Pharmaceutical Discovery and Dr. Alan S. Rosenthal, Vice President Pharmaceutical Discovery and Scientific Affairs, Abbott). |
| 13 May 1999 |
“Molecular targets and compounds for anti-HIV therapy, with special emphasis on reverse transcriptase and protease inhibitors” in the scope of a graduate course on “Medicinal Chemistry: Drug Design and Development”, Department of Chemistry, University of Patras, Patras, Greece (hosts: Prof. Dr. Dionissios Papaioannou and Prof. Dr. John Matsoukas). |
| 7 May 1999 |
Discussions and assistance at the thesis defense (Dr. Sciences) of S. Barthélémy on “Conception de dérivés phénoliques symmétriques conjugués: synthèse et étude de l’activité sur des pathologies impliquant le stress oxydant”, Université Paul Sabatier, Toulouse, France (Chairman of the Jury: Prof. Armand Lattes; Promoter: Prof. Serge Labidalle). |
| 18 February 1999 |
“New developments in anti-HIV chemotherapy”, AminoScience Laboratories, Process Research and Development, Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, Kawasaki, Japan (host: Dr. Kunisuke Izawa, General Manager, Process and Development, Ajinomoto). |
| 18 February 1999 |
Discussions on the development of HIV-cell fusion inhibitors such as T22 ([Tyr5,12, Lys7]-polyphemusin II), Tokyo Medical and Dental University School of Medicine, Bunkyo-ku, Tokyo, Japan (host: Prof. Dr. Naoki Yamamoto). |
| 17 February 1999 |
Discussions on the development of MKC-442 (Emivirine, CoactinonTM) as an anti-HIV drug, Pharmaceuticals and Diagnostics, Mitsubishi Chemical Corporation, Tennoz Central Tower, Shinagawa-ku, Tokyo, Japan (hosts: Dr. Takehiro Takagi, General Manager Business Development, and Dr. Kenichiro Nakao, General Manager, Licensing and Planning, International Operations Department, Mitsubishi Chemical Corporation). |
| 12 December 1998 |
Discussions on the development of new antiviral, including anti-HIV and anti-HBV, agents, Triangle Pharmaceuticals, Inc., Scientific Advisory Board (SAB) Meeting, St. Thomas, Virgin Islands, USA (host: Dr. Phillip A. Furman, Chief Scientific Officer, Vice-President Research, Triangle Pharmaceuticals). |
| 10 December 1998 |
Discussions on the development of new antiviral, including anti-HIV, agents, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA (hosts: Prof. Dr. Katherine Seley, Prof. Dr. Stewart Schneller and Prof. Dr. Leon Zalkow). |
| 28 October 1998 |
“New perspectives for the chemotherapy of HBV infections”, National Taiwan University Hospital, Hepatitis Research Center, Department of Internal Medicine, National Taiwan University (hosts: Prof. Ding-Shinn Chen and Prof. Pei Jer Chen). |
| 28 October 1998 |
Discussion on the preclinical development of antiviral agents, Development Center for Biotechnology (DCB), Taipei, Taiwan, Republic of China (hosts: Dr. Weichen Tien, President, and Dr. Shou-Hsiung Pai, Vice President, DCB). |
| 27 October 1998 |
Round table discussion on the development of anti-HIV, antiHBV, and anti-cancer agents, Institute of Biomedical Sciences (IBMS), Academia Sinica, Taipei, Taiwan, Republic of China (hosts: Dr. Kenneth K. Wu, Director, and Dr. Tsann-Long Su, Deputy Director, IBMS). |
| 27 October 1998 |
“New strategies for the chemotherapy of cancer”, National Health Research Institutes (NHRI), Taipei, Taiwan, Republic of China (host: Dr. Ming-Chu Hsu, Director of Biotechnology and Pharmaceutical Research, NHRI). |
| 26 October 1998 |
“New perspectives for the chemotherapy of HIV infection”, National Yang-Ming University, Taipei, Taiwain, Republic of China (host: Prof. Wu-Tse Liu). |
| 21 October 1998 |
“Perspectives en chimiothérapie antivirale”, Encéphalites infectieuses de l’immunodéprimé, Sixième Journée de Pathologie Infectieuse et Tropicale de Paris Nord, Paris, France (host: Dr. Yves Cohen, Centre de Recherche en Pathologie Infectieuse et Tropicale, Hopitaux Avicenne - Jean Verdier, Bobigny, France). |
| 4 September 1998 |
“New developments in the search for effective anti-HIV chemotherapy”, Frontiers in Antiviral and Anticancer Research, Symposium to honor Professor William H. Prusoff, Yale University School of Medicine, New Haven, Connecticut (host: Prof. Dr. Yung-chi Cheng, Henry Bronson Professor of Pharmacology, Yale University). |
| 2 September 1998 |
Round table panel discussion on novel HIV therapies designed to eradicate residual reservoirs of HIV infected cells in patients under HAART (highly active antiretroviral threapy), New York City, New York, USA (host: Hoechst Marion Roussel Project Management, Frankfurt am Main, Deutschland GmbH). |
| 14 August 1998 |
“Development of bicyclams as anti-HIV drugs”, AnorMed Scientific Advisory Board Meeting, Edgewater Lodge, Whistler, B.C., Canada (hosts: Dr. M.J. Abrams, President, CEO, and Dr. G.J. Henson, COO, AnorMed). |
| 20 July 1998 |
“New trends in the development of anti-HIV agents”, Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The University of Utah, Salt Lake City, Utah, USA (hosts: Prof. Dr. A.-H. Ghanem and Prof. Dr. William I. Higuchi, head of the Department of Pharmaceutics and Pharmaceutical Chemistry). |
| 1 July 1998 |
What will the epidemiological situation for HIV infection be in 2005 ? Future therapeutic standards. Advisory Review Meeting on HIV Therapeutic Vaccines. Pasteur Mérieux Connaught, Geneva, Switzerland (hosts: Prof. Dr. S. Plotkin, Chairman, formerly Medical and Scientific Director, and Dr. R. El Habib, HIV Project Leader at Pasteur Mérieux Connaught). |
| 12 June 1998 |
Discussions and presentations on new drugs and strategies for the treatment of HIV and HBV infections, Scientific Advisory Board Meeting, Triangle Pharmaceuticals, Durham, North Carolina (host: Dr. P.A. Furman, Vice President Research). |
| 27 May 1998 |
Discussions on current and future trends in antiviral chemotherapy and the implications for development of virus-drug resistance, BioMérieux Medical Direction, Marcy-L’Etoile, Venissieux, Lyon, France (host: Dr. S. Lafont, Medical Director). |
| 30 April 1998 |
Chimiothérapie antivirale (Antiviral chemotherapy), Cours de Virologie Systématique, Centre d’Enseignement de l’Institut Pasteur, Paris, France (host: Dr. J.-D. Poveda, Directeur adjoint du Centre de Biologie Médicale Spécialisée, Institut Pasteur). |
| 16 April 1998 |
“New developments in the treatment of HIV infections”, Croatian Academy of Sciences and Arts, Zagreb, Croatia (hosts: Prof. Dr. M. Mintas, Faculty of Chemical Engineering and Technology, University of Zagreb, and Prof. Dr. I. Padovan, President of the Croatian Academy of Sciences and Arts). |
| 15 April 1998 |
“New developments in the treatment of HIV infections”, Biochemisches Institut der Universität Zurich, Department of Pharmacy ETH Zurich, Zurich, Switzerland (hosts: Prof. Dr. M. Nonella, President, Chemischen Gesellschaft, and Prof. Dr. G. Folkers, Head of the Department of Pharmacy, ETH Zurich). |
| 8 April 1998 |
Discussions on the potential use of NNRTIs (non-nucleoside reverse transcriptase inhibitors) for the treatment of HIV infections, Chiron Technologies, Emeryville, California, USA (meeting held in San Diego) (host: Dr. P. Olson, Vice President, Project Management & Planning, Chiron Corporation). |
| 4 April 1998 |
“New developments in antiviral drug research”, LXR Biotechnology Inc., Richmond, California, USA (host: Dr. D.H. Picker, President and Chief Operating Officer of LXR Biotechnology Inc.). |
| 3 April 1998 |
“Inhibitory effects of cidofovir (HPMPC, Vistide®) on the development of hemangiomas and hemangiosarcomas in rats and mice”, and discussions on the development of adefovir (PMEA) and tenofovir (PMPA) for the treatment of HIV and HBV infections, Gilead Sciences, Foster City, California, USA (hosts: Dr. N. Bischofberger, Senior Vice President Research, and Dr. J.C. Martin, Chief Executive Officer, Gilead Sciences). |
| 11 March 1998 |
“Bicyclams (i.e. AMD 3100): inhibition of HIV replication through interference with the interaction of HIV with its coreceptor CXCR4 (fusin)”, The John Hopkins University School of Medicine, Baltimore, Maryland, USA (host: Prof. Dr. Paul S. Lietman, Wellcome Professor of Clinical Pharmacology and Director of the Division of Clinical Pharmacology). |
| 10 March 1998 |
The 1998 Sir Henry Hallett Dale Memorial (Burroughs Wellcome Fund) Lecture “Antiviral drug discovery and development”, The John Hopkins University School of Medicine, Baltimore, Maryland, USA (host: Prof. Dr. Paul S. Lietman, Wellcome Professor of Clinical Pharmacology and Director of the Division of Clinical Pharmacology). |
| 14 December 1997 |
Scientific Advisory Board Meeting (Triangle Pharmaceuticals, Inc.) held at Mauna Lani, Kona, Big Island, Hawaii, USA (hosts: Dr. P.A. Furman, Vice President Research and Chief Scientific Officer, and Dr. D.W. Barry, Chairman and Chief Executive Officer, Triangle Pharmaceuticals, Inc.). |
| 1-2 December 1997 |
Research aspects for viral diseases, Workshop Infectious Diseases, Research Novartis Pharma AG, Basel, Switzerland (hosts: Dr. Reto Naef, Unit Head Basel Research, and Dr. Anis Mir, Head Research Planning). |
| 27 November 1997 |
“Drug-resistant mutants”, lecture delivered at the Viral Hepatitis Peer Group Meeting on “Novel Treatments for Hepatitis”, Royal College of Physicians, London, England (host: Prof. Arie Zuckerman, Dean of the Royal Free Hospital School of Medicine). |
| 6-7 November 1997 |
Infectious Diseases Scientific Advisory Council Review, Pharmaceutical Products Division, Abbott Laboratories, meeting held in La Paloma, Tucson, Arizona, USA (host: Dr. J.J. Plattner, head of Abbott’s Infectious Disease Research Division). |
| 27 October 1997 |
“Ligt er met de nieuwe behandelingsmethoden een genezing van aids in het verschiet ? (Can the new treatment strategies lead to a cure from AIDS ?)”, Sectie Geneeskunde van de Koninklijke Nederlandse Akademie van Wetenschappen, Het Trippenhuis, Amsterdam, The Netherlands (host: Prof. Dr. R.S. Reneman, Voorzitter van de Afdeling Natuurkunde). |
| 24 October 1997 |
“Perspectives for the chemotherapy of AIDS: Is there a cure at the horizon”, Lecture delivered at the Doctor honoris causa (Honorary Doctor) Award Ceremony, University of Athens, Greece (Promotor: Prof. N. Kolocouris, Professor of Pharmacy; Prof. G. Papaioannou, Head of the Department of Pharmacy; Prof. C.A. Dimopoulos, Rector of the University of Athens). |
| 25 August 1997 |
Targets for anti-HIV agents (with particular emphasis on HIV-cell fusion, HIV reverse transcriptase and HIV protease), HIV Strategic Advisory Board Meeting, Agouron Pharmaceuticals, Chicago, Illinois, USA (host: Dr. Peter Johnson, Chief Executive Officer and President, Agouron Pharmaceuticals Inc.). |
| 9 August 1997 |
AMD 3100 blocks HIV infection through interaction with the HIV coreceptor CXCR4 (fusin), Discussions on the development of anti-HIV and anticancer agents, AnorMED Scientific Advisory Board Meeting, Galiano Island, British Columbia (B.C.), Canada (hosts: M.J. Abrams, President, and G.W. Henson, Vice Executive President, AnorMED, Langley, B.C., Canada). |
| 1 August 1997 |
“New opportunities in the development of antiviral agents”, Samsung Fine Chemicals, Daekyung Bldg., Taepyung-Ro, Chung-Ku, Seoul, Korea (hosts: Dr. Kwang Sik Park, General Manager Pharmaceutical Division and Dr. Young K. Park, President Samsung Fine Chemicals). |
| 29 July 1997 |
“New trends in the search for anti-HIV agents”, Discussions on new “non-nucleoside reverse transcriptase inhibitors (NNRTIs)” with Dr. Jong-Chan Son (Principal Research Scientist), Korea Research Institute of Chemical Technology (KRICT), Taejon, Korea (host: Dr. Chong-Kyo Lee, Principal Investigator, KRICT). |
| 16-17 July 1997 |
Research & Strategy Discussions, Grand Pow Wow, Gilead Sciences, Foster City, California, USA (host: Dr. Norbert Bischofberger, Vice President, Research). |
| 21 June 1997 |
“Discovery and therapeutic potential of Cidofovir”, European Symposium, Pharmacia & Upjohn (France), Roma, Italy (host: Dr. L. Lamezec, Chef de Groupe Anti-Infectieux, Pharmacia & Upjohn France). |
| 28 May 1997 |
Discussions on “Development of antiviral agents”, Scientific Advisory Board, Triangle Pharmaceuticals, Durham, North Carolina, USA (host: Prof. Dr. P.A. Furman, Vice President of Research and Chief Scientific Officer). |
| 27 May 1997 |
“New perspectives for the chemotherapy of AIDS”, College of Pharmacy, The University of Georgia, Athens, Georgia, USA (host: Prof. Dr. C.K. Chu, Professor of Medicinal Chemistry). |
| 7 May 1997 |
“Towards an effective chemotherapy of (DNA) virus infections”, Academy of Sciences, Society for Clinical Microbiology, Microbiological Society and Purkyne Society, Prague, Czech Republic (host: RN Dr. A. Holý, Dr.Sc., Director of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences). |
| 6 May 1997 |
“New perspectives for the treatment of HIV infections”, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic (host: RN Dr. A. Holý, Dr. Sc., Director of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences). |
| 30 April 1997 |
“Antiviral chemotherapy: status and future development”, Rigshospitalet, Copenhagen, Denmark (host: Danish Society for Infectious Diseases and Janssen-Cilag, Dr. Henrik Abrahamsen, Product Manager). |
| 23 April 1997 |
Perspectives for the therapy of retrovirus infections (“Perspectieven voor de therapie van retrovirusinfecties”). |
| Voorjaarsvergadering van de Nederlandse Vereniging voor Medische Microbiologie en de Nederlandse Vereniging voor Microbiologie, Werkgroep Klinische Virologie, Lunteren, Nederland (host: Dr. G.J.J. van Doornum, Gemeentelijke Geneeskundige en Gezondheidsdienst Amsterdam). |
| 9 April 1997 |
Discussions on the development of RPR-111423 for the treatment of cytomegalovirus (CMV) infections, Rhône-Poulenc Rorer Recherche-Développement, Advisory Meeting held in Atlanta, Georgia, USA (at the occasion of the Tenth International Conference on Antiviral Research, 6-11 April 1997). |
| 6-7 March 1997 |
Infectious Diseases Research Scientific Advisory Council Meeting, Abbott Laboratories, Abbott Park, Illinois, USA (host: Dr. Alan S. Rosenthal, Vice President Pharmaceutical Discovery, Abbott). |
| 15 January 1997 |
“Le traitement de l’infection à HIV: Nouvelles recherches et perspectives”, le Département des Maladies Infectieuses du Centre Hospitalier de Luxembourg, le Laboratoire de Rétrovirologie et le Centre de Recherche Public-Santé (hosts: Dr. R. Hemmer, Dr. F. Schneider, Dr. V. Arendt, Dr. J.-C. Schmit, Dr.T. Staub, Dr. D. Hansen-Koening, Président du CRP-Santé). |
| 8 January 1997 |
Discussions on the development of anti-HIV agents (i.e. MKC-442) and treatment management for HIV disease, Scientific Advisory Board Meeting, Triangle Pharmaceuticals, Durham, North Carolina, USA (host: Dr. Phillip A. Furman, Vice President, Research). |
| 9 December 1996 |
Presentations on “Drugs for the Treatment of AIDS” to Vector Securities, Business Week, Furman Selz, Treatment Issues Newsletter, Edelman Public Relations, New York, NY, USA (host: Mariann L. Caprino, Vice-President of Edelman Healthcare Worldwide). |
| 31 October 1996 |
“Therapeutic potential of acyclic nucleoside phosphonates as antiviral agents”, Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain (host: Prof. Dr. F. Fernandez-Gonzalez). |
| 30 October 1996 |
“New developments in the search for an effective chemotherapy of HIV infections”, Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain (host: Prof. Dr. F. Fernandez-Gonzalez). |
| 3-4 October 1996 |
Scientific Advisory Council Meeting, Abbott Laboratories, Illinois, USA (host: Dr. A.S. Rosenthal, Divisional Vice President, Pharmaceutical Discovery). |
| 13 September 1996 |
“The art of antiviral drug development”, Gilead Sciences, Foster City, California, USA (host: Dr. J.C. Martin, President, Chief Executive Officer). |
| 31 July 1996 |
Development of antiviral and anticancer agents, Scientific Advisory Board Meeting, Triangle Pharmaceuticals, Durham, North Carolina, USA (host: Dr. Phillip A. Furman, Vice President Research). |
| 29 July 1996 |
Distinguished Biomedical Lecture on “New Developments in Anti-HIV Chemotherapy”, Madren Center, Medicinal Chemistry Symposium, Chemistry Department, Greenville Hospital System and Clemson University Biomedical Cooperative, Clemson, South Carolina, USA (host: Prof. Dr. J.D. Gangemi). |
| 5 June 1996 |
“Development of new anti-HIV agents and strategies to cope with the HIV drug resistance problem”, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina (host: Prof. Dr. Celia E. Coto, Laboratorio de Virologia, Departemento de Quimica Biologica). |
| 25 May 1996 |
“The development of anti-HIV agents”, Rational Drug Design Laboratories, 4-1-1 Misato, Matsukawa, Fukushima, Japan (host: Dr. Kiyoshi Okazaki, General Manager of Rational Drug Design Laboratories). |
| 24 April 1996 |
Discussions on the development of acyclic nucleoside phosphonates (i.e. HPMPC, cHPMPC, PMEA, PMEG, Bis(POM)PMEA, PMPA) for the treatment of DNA virus [i.e. herpes (HSV, VZV, CMV, ...) and papillomaviruses and retrovirus (i.e. HIV) infections (hosts: Dr. J.C. Martin, Chief Executive Officer, and Dr. Norbert Bischofberger, Vice President Research, Gilead Sciences). |
| 22 April 1996 |
“Perspectives for the chemotherapy of HIV infections”, Institut Català de la Salut, Hospital Universitari “Germans Trias i Pujol”, Badalona, Barcelona, Catalonia, Spain (host: Dr. B. Clotet/Dr. L. Ruiz, Retrovirology and HIV Unit). |
| 17 April 1996 |
“Perspectives for antiviral chemotherapy”, Discussions on the development of BVDU (Brivudin) as an antiviral drug, Menarini Ricerche Sud, Firenze, Italy (host: Prof. Dr. A. Giachetti, Director of Drug Discovery). |
| 18 March 1996 |
“Resistance aux antiviraux”, Méthodes Expérimentales et Cliniques d’Evaluation des Agents Anti-infectieux”, Module “Antiviraux” de l’Enseignement Approfondi, Faculté de Médecine, Université Bichat-Claude Bernard, Paris (hosts: Prof. Dr. C. Carbon, Médecine Interne, C.H.U. Bichat-Claude Bernard et Prof. Dr. F. Morinet, Service de Microbiologie, Hôpital Saint Louis, Paris). |
| 6-8 March 1996 |
Meeting of the Scientific Advisory Council, Abbott Laboratories, Abbott Park, Illinois, USA (host: Dr. A.S. Rosenthal, Divisional Vice President, Pharmaceutical Discovery). |
| 22 November 1995 |
"New perspectives for the chemotherapy of HIV infection", Institut für Pharmazeutische Chemie, Leopold-Franzens-Universität, Innsbruck, Austria (host: Prof. Dr. G. Heinisch, President, Österreichische Pharmazeutische Gesellschaft). |
| 15 November 1995 |
"Targets and trends in antiviral chemotherapy", Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands (host: Prof. Dr. B. Rosenwirth). |
| 1 November 1995 |
"New developments in the treatment of HIV infections", Division of Human Retroviruses, Center for Chronic Viral Diseases, Faculty of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan (host: Dr. Masanori Baba, Professor). |
| 30 October 1995 |
"Molecular targets for and activity spectrum of antiviral agents" and "The potential of non-nucleoside reverse transcriptase inhibitors for the treatment of human immunodeficiency virus type 1 infections", Mitsubishi Chemical Corporation Yokohama Research Center, Kamoshida, Aoba-ku, Yokohama, Japan (host: Dr. M. Ubasawa, Research and Development Division). |
| 5-6 October 1995 |
Scientific Advisory Council Meeting, Abbott Laboratories, Abbott Park, Illinois, USA (host: Dr. A.S. Rosenthal, Vice President, Pharmaceutical Discovery). |
| 27 September 1995 |
Discussions on phase III clinical study of bis(POM)PMEA (Adefovir Dipivoxil) for the treatment of AIDS with different investigators, Gilead Sciences (Foster City, California, USA), Copenhagen, Denmark (hosts: Dr. H. Jaffe, Dr. M. Hitchcock and Dr. J.C. Martin, Executive Vice President for Research & Development, Gilead Sciences). |
| 29 June 1995 |
Discussions on therapeutic usefulness of guanosin octed based oligonucleotides (hosts: Dr. R.F. Rando, Dr. P. Cossum and Dr. J.M. Chubb, President, Triplex Pharmaceutical Corporation, Woodlands, Texas, USA). |
| Discussions on therapeutic usefulness of bicyclams and acyclic nucleoside phosphonates (i.e. HPMPC), Rhône-Poulenc Rorer, Vitry sur Seine, Paris, France (hosts: Dr. A. Bousseau, Dr. N. Dereu and Dr. H. Fliri, Director Anti-Infective Research). |
| 21 March 1995 |
"New anti-herpesvirus agents (Nieuwe anti-herpes middelen)", Minisymposium "Nieuwe ontwikkelingen in de diagnostiek en het beleid van herpesvirusinfecties", Academisch Ziekenhuis Maastricht, Nederland (The Netherlands) (host: Prof. Dr. C. Bruggeman). |
| 13 December 1994 |
"CMV antivirals" (lecture given jointly with Dr. J. Neyts), Rhône-Poulenc Rorer Recherche-Développement, Centre de Recherche de Vitry-Alfortville, Vitry sur Seine, France (host: Dr. N. Dereu, Director Medicinal Chemistry Department). |
| 11 November 1994 |
"Recent advances in the chemotherapy of AIDS", Department of Chemistry & Biochemistry, Brigham Young University, Provo, Utah, USA (host: Prof. Dr. Morris J. Robins, J. Rex Goates Professor of Chemistry). |
| 9 November 1994 |
General discussions and summation from a researcher's viewpoint on "Antisense drug strategies", Genta Virology Summit Meeting, Genta Incorporated, San Diego, California, USA (host: Dr. Donald H. Picker, Senior Vice President of Research and Development). |
| 7-8 November 1994 |
Discussions on the development of acyclic nucleoside phosphonates [Cidofovir (Vistide) and bis-POM-PMEA] for the treatment of herpes- and retrovirus infections, Gilead Sciences, Foster City, California, USA (hosts: Dr. Norbert Bischofberger, Vice-President of Organic Chemistry, and Dr. John C. Martin, Executive Vice President, Research and Development). |
| 3 November 1994 |
"New developments on anti-HIV chemotherapy", Istituto di Ricerche di Biologia Moleculare (IRBM) P. Angeletti, Pomezia (Roma), Italy (host: Dr. J. Jiricny, Director). |
| 25 October 1994 |
"Les cibles virales et les stratégies thérapeutiques" (invited plenary lecture). Les Journées Scientifiques du Pôle Universitaire Européen (President: Prof. Dr. Edmond Fischer), Interface Chimie Biologie, Les Antiviraux, Faculté de Médecine, Université Montpellier I, France (host: Prof. Dr. J.-L. Imbach, Université Montpellier II). |
| 14 October 1994 |
"New achievements with HIV inhibitors", Biochem Thérapeutique Inc., Biochem Pharma Inc., Laval, Quèbec, Canada (host: Dr. Tarek S. Mansour, Director of Medicinal and Developmental Chemistry, and Dr. G. Dionne, President of BioChem Therapeutic). |
| 26 September 1994 |
Discussion on the development of bicyclams as anti-HIV drugs, Sandoz Forschungsinstitut, Vienna, Austria (host: Dr. R. Datema, Director Research and Development). |
| 11 August 1994 |
"New leads in the development of anti-HIV drugs", Central Research Laboratories, Ajinomoto Company, Kawasaki, Japan (host: Dr. K. Izawa, Director, Process Development Laboratories). |
| 11 February 1994 |
"Current developments in AIDS research: what to expect from HIV chemotherapy", Department of Virology, Institut für Mikrobiologie und Hygiene, Klinikum der Albert-Ludwigs-Universität Freiburg, Germany (host: Prof. Dr. O. Haller, Director of the Institut für Mikrobiologie und Hygiene). |
| 31 January 1994 |
"Development of new antiviral, anti-AIDS and anticancer agents", Norsk Hydro Research Center Porsgrunn, Oslo, Norway (hosts: Dr. M.L. Sandvold, Dr. F. Myhren, and Dr. E.O. Strutz, Director of Technology and Development). |
| 27 January 1994 |
"Search for antiviral compounds effective against the human immunodeficiency virus", Centre National de la Recherche (CNRS), Reconnaissance et Interaction Moléculaire (Réactivité des Molécules Fluorées), Centre d'Etudes Pharmaceutiques de Châtenay-Malabry (hosts: Dr. M. Langlois, Dr. J.-P. Bégué, Directeur de Recherche, CNRS). |
| 9 December 1993 |
"Recent developments on the chemotherapy of HIV infections", Forschungsleitung, Hoechst Aktiengesellschaft, Hoechst, Frankfurt, Germany [hosts: Dr. W. Scheibitz & Dr. U.-H. Felcht, Mitglied des Vorstands (President Research & Development)]. |
| 23 November 1993 |
"Current state of development of antiviral agents, in particular against herpes- and retroviruses", Genta Inc., General Atomics Court, San Diego, California, USA (host: Dr. D.H. Picker, Senior Vice President of Research and Development). |
| 22 November 1993 |
"Non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1", Gilead Sciences, Foster City, California, USA (host: Dr. J.C. Martin, Executive Vice President for Research and Development). |
| 12 October 1993 |
"Antiviral therapy, competition of BVDU versus other antivirals", Discussions on the role of BVDU in Antiviral Therapy, Berlin-Chemie Aktiengesellschaft, Berlin, Germany (hosts: Prof. Dr. K.-D. Kaufmann and Prof. Dr. A. Giachetti, A. Menarini, Firenze, Italy). |
| 24 September 1993 |
Discussions on the Development of Bicyclams as Anti-HIV Drugs, Materials Technology Division, Johnson Matthey Inc., West Chester, Pennsylvania, USA (hosts: Dr. G.W. Henson and M. Abrams, Biomedical Research Worldwide Manager). |
| 23 September 1993 |
"Recent progress with anti-HIV agents, particularly reverse transcriptase inhibitors", Materials Technology Division, Johnson Matthey Inc., West Chester, Pennsylvania, USA (host: Dr. G.W. Henson, Director). |
| 22 September 1993 |
Discussions on Antiviral Drug Discovery and Development, Avid Therapeutics Inc., University City Science Center, Philadelphia, Pennsylvania, USA (hosts: Dr. E.J. Thomas, Executive Vice President, and Dr. F.H. Anthony, President). |
| 21 May 1993 |
"Chemotherapy of herpesvirus infections", Department of Ophthalmology, University of Bristol, Bristol, United Kingdom (hosts: Dr. M. Berry and Prof. Dr. D.L. Easty, Professor of Ophthalmology). |
| 20 May 1993 |
"The search for a drug cure for HIV infection", Association of Clinical Biochemists Wales Region on "The HIV Epidemic", University Hospital of Wales, Cardiff, Wales (host: Dr. Rhys John, University Hospital of Wales, Cardiff). |
| 12 May 1993 |
"New developments in the chemotherapy of herpesvirus infections", Pharma-Synthese, Hoechst Aktiengesellschaft, Frankfurt am Main, Germany (hosts: Dr. I. Winkler and Prof. Dr. G. Seibert, Head of Research Antiinfectives). |
| 30 April 1993 |
Discussion on the development of bicyclam JM3100 (SDZ 282-791) and cyclosporine derivative SDZ 211-811 as anti-HIV agents, Antiretroviral Agents Meeting, Sandoz Research Institute, Venice (host: Dr. M. Tolpin, Director Clinical Research, Sandoz USA). |
| 20 April 1993 |
"Tour d'horizon (point de vue) à propos des différentes molécules à explorer en fonction de diverses cibles pour la chimiothérapie du SIDA", Agence Nationale de Recherches sur le SIDA (ANRS), Paris, France (host: Prof. Dr. J.-P. Lévy, Directeur de l'ANRS). |
| 19 March 1993 |
Discussions on the development of acyclic nucleoside phosphonates (HPMPC, PMEA and their derivatives) and prodrugs thereof, Gilead Sciences, Foster City, California, USA (host: Dr. John C. Martin, Executive Vice President for Research and Development). |
| 18 March 1993 |
"New developments in the search for anti-HIV agents", Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Illinois, USA (host: Dr. P.S. Mohan, Assistant Professor of Medicinal Chemistry and Hans Vahlteich Research Scholar). |
| 8 February 1993 |
"Strategies to prevent or overcome resistance of HIV to antiviral drugs (i.e. bicyclams"), Meeting on Preclinical Development of Bicyclam Derivatives, Sandoz Forschung, Basel, Switzerland (host: Dr. R. Datema, Sandoz Forschungsinstitut, Vienna, Austria). |
| 8 January 1993 |
Program Committee Meeting of the Sixth International Conference on Antiviral Research, National Institutes of Health, Bethesda, Maryland (host: Dr. G.J. Galasso, Associate Director NIH). |
| 5 October 1992 |
"Anti-HIV activity of bicyclams: virology, mechanism of action and resistance", Sandoz Forschungsinstitut, Vienna, Austria (host: Dr. R. Datema, Director, Antiretroviral Therapy Program). |
| 23 September 1992 |
"Antiviral activity profiles of nucleosides and nucleotides", Gilead Sciences, Foster City, California, USA (hosts: Dr. N. Bischofberger, Dr. J.C. Martin and Dr. M. Riordan, President and Chief Executive Officer of Gilead Sciences). |
| 22 September 1992 |
"New approaches towards the chemotherapy of HIV infections", Center for AIDS Research, Stanford University Medical Center, Stanford, California, USA (host: Prof. Dr. T.C. Merigan, Chairman of the Center for AIDS Research at Stanford). |
| 21 September 1992 |
"New chemical approaches to the chemotherapy of HIV infections", Department of Chemistry (Henry Eyring Building), The University of Utah, Salt Lake City, Utah, USA (hosts: Prof. Dr. W.G. Bentrude and Prof. Dr. P.J. Stang, Chairman of the Department of Chemistry). |
| 28 August 1992 |
"New candidate compounds for the treatment of human immunodeficiency virus (HIV) infections", Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana, USA (host: Prof. Dr. Mark Cushman, Professor of Medicinal Chemistry). |
| 27 August 1992 |
"New antiviral agents effective against HIV (human immunodeficiency virus", Baxter Healthcare Corporation Applied Sciences, Technology Park, Round Lake, Illinois, USA (host: Dr. Steven F. Josephs). |
| 1 August 1992 |
"New perspectives for the treatment of HIV infections", Department of Microbiology, Fukushima Medical College, Fukushima, Japan (hosts: Dr. M. Baba and Prof. Dr. S. Shigeta, Chairman of the Department of Microbiology). |
| 31 July 1992 |
"The problem of HIV-1 resistance to HIV-1-specific reverse transcriptase inhibitors", Discussion on the development of HEPT derivatives for the treatment of HIV infections, Research Center, Mitsubishi Kasei Corporation, Kamoshida-cho, Midori-ku, Yokohama, Japan (hosts: Dr. S. Yuasa and Dr. K. Ohtsu, Director of Pharmaceuticals Laboratory). |
| 29 July 1992 |
"New inhibitors of HIV replication", Department of Microbiology, School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan (hosts: Dr. H. Nakashima and Prof. Dr. N. Yamamoto, Chairman of the Department of Microbiology). |
| 27 July 1992 |
"Perspectives for the development of new anti-HIV and other antiviral agents", Central Research Laboratories, Ajinomoto Co., Suzuki-cho, Kawasaki, Japan (hosts: Dr. K. Izawa and Dr. H. Shiragami, Process Development Laboratories, Ajinomoto Co.). |
| 26 June 1992 |
"New perspectives for the treatment of HIV-1 infections", Korea Research Institute of Chemical Technology, Daejeon, Korea (hosts: Dr. Chong-Kyo Lee, Dr. Zaesung No and Dr. Yung Bog Chae, President). |
| 22 May 1992 |
Discussions on the perspectives for the clinical use of new anti-HIV agents, Vyrex Corporation Research and Development, La Jolla, California, USA (hosts: Dr. S.S. Hendler & Dr. R. Sanchez). |
| 21 May 1992 |
"Update on development of new anti-HIV agents", Genta Incorporated, General Atomics Court, San Diego, California, USA (host: Dr. D.H. Picker, Senior Vice President Research and Development). |
| 10 April 1992 |
Discussion on "New leads for the development of anti-HIV compounds", Centre de Gentilly, Centre de Toulouse, Sanofi Recherche, Gentilly, Paris, France (hosts: Dr. M. Pascal & Dr. J.-P. Maffrand, Directeurs Scientifiques). |
| 14 March 1992 |
Discussions on "Development of phosphonylmethoxyalkylpurines and -pyrimidines (HPMPC, PMEA, etc.) as therapeutic agents against viral diseases", Gilead Sciences, Foster City, California, USA (hosts: Dr. J.C. Martin, Vice President, Research and Development, and Dr. M. Riordan, Chief Executive Officer, Gilead Sciences). |
| 25 February 1992 |
Discussion of Research Project on "Anti-HIV Activity of Macrocyclic Polyamines", Johnson Matthey Materials Technology Division - Sandoz Forschungsinstitut Vienna, Sandoz Pharma, Basel, Switzerland (host: Dr. R. Datema, Director of Preclinical Development). |
| 24 February 1992 |
Discussion on "Anti-HIV Activity of Bicyclam Derivatives", Johnson Matthey Materials Technology Division (West Chester, Pennsylvania, USA), Basel, Switzerland (host: Dr. G.W. Henson, Manager Preclinical and Clinical Development). |
| 8 February 1992 |
"Perspectives des antiviraux", Service des Maladies Infectieuses, Hôpital Bichat Claude-Bernard, Paris, France (hosts: Dr. C. Leport and Prof. Dr. J.-L. Vildé, Chef de Service). |
| 6 December 1991 |
"Overzicht van de antivirale geneesmiddelen gebruikt in de behandeling van herpesvirusinfecties", Boerhaave Cursus over de Kliniek en Behandeling van Herpesvirus Infecties, Faculteit der Geneeskunde, Rijksuniversiteit Leiden, The Netherlands (host: Prof. Dr. R. van Furth, Voorzitter Boerhaave Cursus). |
| 19-20 November 1991 |
Discussion with Dr. J.C. Martin and Dr. M. Riordan (Gilead Sciences, Foster |
| City, California, USA) on the development of (S)-1-(3-hydroxy-2-phosphonylmethoxyypropyl)cytosine (HPMPC) for the treatment of herpesvirus infections, Bethesda, Maryland, USA (hosts: Dr. J.C. Martin and Dr. M. Riordan, Vice-President and President, Gilead Sciences). |
| 11 September 1991 |
"Novel leads in the development of antiviral compounds for the therapy of retroviral and herpes virus infections", Department of Chemistry, Oakland University, Rochester, Michigan, USA (host: Prof. Dr. R.C. Taylor). |
| 10 September 1991 |
"Bicyclams and polyoxometalates as inhibitors of HIV replication", presentation in cooperation with G. Henson, M. Abrams and D. Picker, Johnson Matthey Pharmaceutical Research, West Chester, Pennsylvania, USA, at the Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan, USA (host: Dr. Richard F. Haff, Vice-President). |
| 12 July 1991 |
"New advances in research on anti-HIV agents", Biomedical Research, Materials Technology Division, Johnson Matthey, West Chester, Pennsylvania, USA (host: Dr. D.H. Picker, Vice-President). |
| 11 July 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Medical Research Division, Lederle Laboratories, American Cyanamid Company, Pearl River, New York, USA (host: Dr. F.P. Tally, Executive Director, Infectious Disease & Molecular Biology Research). |
| 28 May 1991 |
"New developments in antiviral chemotherapy", Department of Chemistry, University of South Florida, Tampa, Florida, USA (host: Prof. Dr. S.W. Schneller, Department of Chemistry). |
| 22 May 1991 |
"Nucleoside and non-nucleoside analogues: therapeutic potential for the treatment of retrovirus and herpesvirus infections", Boehringer Ingelheim Pharmaceuticals Research and Development, Ridgefield, Connecticut, USA (hosts: Dr. M.R. Matteo and Dr. V.J. Merluzzi). |
| 20 May 1991 |
Discussions on the antiviral activity/toxicity profile of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (BMY-41671), Pharmaceutical Research Institute, Bristol-Myers Squibb, Wallingford, Connecticut, USA (host: Dr. J.A. Vida, Vice-President of Licensing). |
| 14 May 1991 |
"New developments in the search of anti-HIV agents", Laboratoire de Chimie de Coordination, Centre National de la Recherche Scientifique (CNRS), Toulouse, France (host: Prof. Dr. B. Meunier). |
| 24 April 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Sandoz Forschungsinstitut, Vienna, Austria (host: Prof. Dr. B. Rosenwirth). |
| 23 April 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Eli Lilly Laboratories, Indianapolis, Indiana, USA (host: Dr. C. Lopez). |
| 22 April 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Smith Kline Beecham, King of Prussia, Pennsylvania, USA (host: Dr. S.R. Petteway). |
| 18 April 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Glaxo International House, Ealing London, England (host: Dr. M.G. Grey, International Licensing Director). |
| 17 April 1991 |
Antiviral (anti-HIV) activity of bicyclam derivatives and polyoxometalates (Johnson Matthey Materials Technology Division), Ciba-Geigy AG, Basel, Switzerland (host: Dr. M. Clausen, Director of Licensing). |
| 15 April 1991 |
"Present situation in the field of antivirals", followed by discussions on strategies towards the development of antiviral drugs, Sandoz Forschungsinstitut, Vienna, Austria (hosts: Prof. Dr. B. Rosenwirth and Prof. Dr. H. Bachmayer). |
| 9 April 1991 |
"Combination of ribavirin with dideoxyinosine (DDI) in the treatment of HIV infections", Round Table on Ribavirin, ICN Pharmaceuticals, Amsterdam, The Netherlands (host: Dr. L.J. Lewandowski, Vice President, Medical Affairs, ICN Pharmaceuticals). |
| 5 April 1991 |
Discussion on the systemic (oral and parenteral) treatment of varicella-zoster virus (VZV) infections in immunocompromised patients, Berlin-Chemie AG, Berlin, Germany (host: Prof. Dr. sc. K. Kaufmann, Direktor für Forschung, Berlin-Chemie). |
| 18 March 1991 |
Discussions on the activity of modified (acylated) heparin derivatives against retrovirus infections in vitro and in vivo, Centre Choay, Sanofi Recherche, Gentilly Cedex, France (host: Dr. J. Choay, President Choay Center). |
| 26 January 1991 |
Program Committee Meeting of the Fourth International Conference on Antiviral Research, National Institutes of Health, Bethesda, Maryland (host: Dr. G.J. Galasso, Associate Director NIH). |
| 25 January 1991 |
Discussion on "Clinical development of new dextran sulfate derivatives as anti-HIV agents" with Prof. P.S. Lietman (Division of Clinical Pharmacology), The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (host: Prof. Dr. P.S. Lietman, Director of Clinical Pharmacology). |
| 1 December 1990 |
"Ribavirin combination with purine 2',3'-dideoxynucleosides (The place of ribavirin in the therapy of HIV infection)", World AIDS Day, The Royal College of Physicians of Ireland, Dublin, Ireland (host: Dr. R.A. Smith, Vice President ICN Pharmaceuticals). |
| 29 November 1990 |
"Nouvelles approches pour la chimiothérapie des infections à HIV et CMV", Centre de Biophysique Moléculaire du Centre National de la Recherche Scientifique (CNRS), Université d'Orléans, Orléans, France (host: Prof. Dr. M. Monsigny, Directeur du CNRS). |
| 20 November 1990 |
"Anti-HIV chemotherapy", Centre de Recherche de Vitry-Alfortville, Rhône-Poulenc Santé, Vitry sur Seine Cedex, France (host: Dr. A. Zerial, Head Anti-HIV Unit Biology Department). |
| 10 October 1990 |
"Recent developments in the antiviral therapy of AIDS", Institut für Organische Chemie der Universität Wien, Vienna, Austria (host: Prof. Dr. E. Zbiral). |
| 10 October 1990 |
Round Table presentation on "New leads in the development of anti-HIV agents", Sandoz Forschungsinstitut, Vienna, Austria (host: Prof. Dr. B. Rosenwirth). |
| 3 October 1990 |
"Recent developments in the search for new anti-HIV drugs", Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), National Institutes of Health (NIH), Bethesda, Maryland, USA, 3 October 1990 (host: Dr. William M. Egan, Chief of the Biophysics Laboratory). |
| 14 June 1990 |
"New perspectives for the treatment of herpes- and retrovirus infections", Jahrestagung der Österreichischen Gesellschaft für Chemotherapie, Hörsäle der Kopfklinik der Universität Innsbruck, Innsbruck, Austria (host: Prof. Dr. B. Rosenwirth, Sandoz Forschungsinstitut, Vienna, Austria). |
| 8 June 1990 |
Executive Committee Meeting of the International Society for Antiviral Research, University of Alabama, Birmingham, Alabama, USA (hosts: Prof. Dr. Earl R. Kern and Prof. Dr. R.J. Whitley). |
| 4-7 June 1990 |
University of South Carolina Distinguished Lecturer in Biomedical Sciences, University of South Carolina, Columbia, South Carolina, USA. |
| 4 June 1990"The design and development of magic bullets - historical perspectives in chemotherapy" (host: Prof. Dr. J. David Gangemi, School of Medicine). |
| 5 June 1990"Drug design and discovery - the chemistry and biochemistry of antiviral nucleosides" (host: Prof. Dr. R. Bruce Dunlap, College of Science and Mathematics). |
| 6 June 1990"Pre-clinical drug development - the biochemistry, pharmacology, and molecular biology of nucleoside antimetabolites" (host: Prof. Dr. Sandra H. Berger, College of Pharmacy). |
| 7 June 1990"Clinical evaluation of new antivirals and anti-cancer agents - therapeutic activity and toxicity" (host: Prof. Dr. William P. Schmidt, Richland Memorial Hospital). |
| 8 June 1990"New developments in AIDS therapy and future directions" (host: Prof. Dr. J. David Gangemi, Richland Memorial Hospital). |
| 3 April 1990 |
"New developments in search for effective anti-HIV agents", and discussions on the design and development of new anti-HIV compounds, Sandoz Forschungsinstitut, Vienna, Austria (hosts: Prof. Dr. B. Rosenwirth, Prof. H. Gstach and Prof. Dr. P. Dukor). |
| 23 March 1990 |
"Nouveaux développement dans nos recherches sur les produits anti-HIV", Institut Curie, Paris, France (host: Dr. Pierre Demerseman). |
| 22 March 1990 |
Discussion sur le développement de dérivés de l'héparine comme agents anti-HIV et antiviraux, Institut Choay, Sanofi Recherche Centre Choay, Gentilly, France (host: Dr. Jean Choay, Director). |
| 2-4 March 1990 |
Program Committee Meeting Third International Conference on Antiviral Research (Brussels, Belgium, April 22-27, 1990), National Institutes of Health, Bethesda, Maryland, USA (hosts: Prof. Dr. R.J. Whitley, President of the International Society for Antiviral Research and Dr. G.J. Galasso, Adjunct-Director of the National Institutes of Health). |
| 22 January 1990 |
Discussions on the future of antiviral chemotherapy with Dr. N. Ishida (President of Intelligent Cosmos Research, Sendai) and his Excellence, Tokuma Utsunomiya [Member of the House of Councillors (National Diet (Senate) of Japan), and President of Minophagen Pharmaceutical], Shimizu, Chiyoda-ku, Tokyo, Japan. |
| 22 January 1990 |
"In search of an effective chemotherapy for AIDS", Fukushima Medical College, Hikarigaoka, Fukushima, Japan (host: Prof. Dr. S. Shigeta, Chairman of the Department of Bacteriology). |
| 20 January 1990 |
"New lead compounds in antiviral chemotherapy", Tanabe Seiyaku Company, Kashima 3-chome, Yodogawa-ku, Osaka, Japan (host: Dr. Y. Iwasawa, General Manager). |
| 18 January 1990 |
"Chemotherapy of HIV infections", Aichi Cancer Center Research Institute, Tashiro-cho, Chikusa-ku, Nagoya, Japan (host: Dr. K. Ono). |
| 17 January 1990 |
"Current trends in antiviral chemotherapy", Mitsubishi Kasei Corporation, Marunouchi 2-chome, Chiyoda-ku, Tokyo, Japan (hosts: Dr. S. Katada, Dr. K. Ohtsu and Dr. H. Ishikawa, Managing Director). |
| 17 January 1990 |
"In search of an effective chemotherapy for AIDS", School of Pharmaceutical Sciences, Showa University, Hatanodai, Shinagawa-ku, Tokyo, Japan (host: Prof. Dr. T. Miyasaka). |
| 6 December 1989 |
"New developments in the chemotherapy of AIDS", Oncogen, Seattle, Washington, USA (hosts: Dr. P. Senter, Dr. M. Gorman, General Manager, and Dr. G. Todaro, Scientific Director). |
| 4 December 1989 |
"New developments in the search for effective anti-HIV agents", Pharmaceutical Research and Development Division, Bristol-Myers Company, Wallingford, Connecticut, USA (host: Dr. J.C. Martin, Associate Director of Antiinfective Chemistry). |
| 21 November 1989 |
"Antiviral approaches to the chemotherapy of AIDS", International Scientific Committee Meeting on Antivirals, Farmitalia Carlo Erba, Milan, Italy (host: Dr. R. Roncucci, Director of Research and Development). |
| 28 September 1989 |
"New antiviral agents with clinical potential", Festkolloquium (aus Anlass des 65. Geburtstages under der Emeritierung von Prof. Dr. H.A. Rosenthal), Bereichs Medizin (Charité) der Humboldt-Universität zu Berlin, German Democratic Republic (host: Prof. Dr. H.A. Rosenthal, Direktor des Institutes für Virologie). |
| 20 September 1989 |
Discussion on the development of sulfated polysaccharides (i.e.dextran sulfate) as potential anti-AIDS drugs, Pfeifer & Langen, Dormagen, Köln, Federal Republic of Germay (host: Dr. H. Giehring, Hauptverwaltung). |
| 4 September 1989 |
"The Rega Institute for Medical Research: European Community (EC) centralized facility and concerted action for design, synthesis and evaluation of new antiviral compounds against AIDS", EC Project Management Group on Basic Research AIDS, Istituto Superiore di Sanità, Rome, Italy (host: Prof. Dr. G.B. Rossi). |
| 14 June 1989 |
"Perspectives for the chemotherapy of AIDS", Austrian Chemical Society, Institut für Organische Chemie, Technische Universität (Erzherzog Johann Universität), Graz, Austria (host: Prof. Dr. H. Griengl). |
| 13 June 1989 |
Discussion on development of anti-HIV drugs for the treatment of AIDS, Sandoz Forschungsinstitut, Vienna, Austria (hosts: Prof. Dr. B. Rosenwirth and Prof. P. Dukor, Director of the Sandoz Forschungsinstitut). |
| 21 April 1989 |
"Recent developments on anti-HIV chemotherapy", Division of Tumor and Virus Research, Ciba-Geigy Ltd, Basle, Switzerland (host: Dr. J. Lazdins). |
| 6 April 1989 |
"Leading compounds for the chemotherapy of AIDS and their mechanism of action", Laboratory of Molecular Biology (LMB), Medical Research Council (MRC), Cambridge, England (hosts: Dr. M.J. Gait and Dr. M.F. Perutz). |
| 17 March 1989 |
Round Table discussion on the synthesis of oligonucleotides (2-5A analogues) and dideoxynucleoside pyridinium derivatives with the research group of Dr. P.F. Torrence, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA (host: Dr. P.F. Torrence, Laboratory of Biomedical Chemistry). |
| 16 March 1989 |
"New perspectives for the chemotherapy of AIDS", Wilson Hall, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA (host: Dr. J.S. Driscoll, Chief, Laboratory of Medicinal Chemistry, Developmental Therapeutics Program, Division of Cancer Treatment). |
| 14 and 15 March 1989 |
Board of Directors Meeting of the International Society for Antiviral Research, |
| Southern Research Institute, Birmingham, Alabama, USA (participants: A.K. Field, G.J. Galasso, E.R. Kern, W.M. Shannon and R.J. Whitley). |
| 14 March 1989 |
Round Table discussion on antiviral activity of nucleoside analogues with Staff Members of Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, USA (host: Dr. S.R. Jaskunas, Head of Molecular Biology Research). |
| 13 March 1989 |
"New developments on chemotherapy for AIDS", Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana, USA (hosts: Dr. S.R. Jaskunas, Head of Molecular Biology Research, and Dr. C. Lopez, Director of Virology Program). |
| 27 February 1989 |
"Recent developments in anti-AIDS chemotherapy", Sandoz Research Institute, Vienna, Austria (hosts: Prof. Dr. B. Rosenwirth and Dr. P. Dukor, Director of Research and Development). |
| 12 December 1988 |
"New perspectives for the chemotherapy of AIDS", Biochemical Research Center, Boehringer Mannheim GmbH, Penzberg, Federal Republic of Germany (host : Dr. E. Koch) |
| 5 December 1988 |
"Recent approaches towards the chemotherapy of HIV infection" & "Table ronde sur les antiviraux en développement", Strasbourg Research Center, Merrell Dow Research Institute, Strasbourg, France (host : Dr. S. Halazy). |
| 30 November 1988 |
"Les antiviraux en développement", Assemblée Générale de la Société Française de Chimie Thérapeutique, Faculté de Pharmacie, Paris, France (host : Prof. Dr. M. Miocque, Président de la Société de Chimie Thérapeutique). |
| 30 November 1988 |
Discussion on anti-HIV research and strategies, Rhône-Poulenc (Centre de Recherches de Vitry), La Croix de Berny, France (host : Dr. A. Zerial) |
| 4 November 1988 |
"Recent progress with the phosphonylmethoxyalkylpurine and -pyrimidine derivatives", Pharmaceutical Research and Development Division, Bristol-Myers Company, Wallingford, Connecticut, USA (host : Dr. J.C. Martin). |
| 27 October 1988 |
"Trends in de ontwikkeling van antivirale middelen", Openingssymposium van de Nederlandse Vereniging voor Farmaceutische Wetenschappen, Utrecht, The Netherlands (host : Prof. Dr. D.K.F. Meijer, Rijksuniversiteit Groningen). |
| 26 October 1988 |
Discussion on the development of sulfated polysaccharides as anti-AIDS drugs, Organon International B.V. (Pharma Division), Oss, The Netherlands (hosts : Dr. F. den Hollander, Dr. H.C.J. Ottenheijm and Dr. K. Wiedhaup, Director of Research and Development). |
| 23 October 1988 |
"Nouveaux médicaments antiviraux en cours de développement, spécialement pour le traitement du S.I.D.A.", Congrès des Pharmaciens du Nord - Pas-de-Calais, Faculté de Pharmacie, Lille, France (host : Prof. Dr. M. Debaert). |
| 6 September 1988 |
"Recent developments in antiviral chemotherapy", Department of Microbiology/Immunology, College of Medicine, Northeastern Ohio Universities, Rootstown, Ohio, USA (host : Prof. Dr. J.J. Docherty, Chairman of the Department of Microbiology/Immunology). |
| 19 August 1988 |
Discussion on the development of new antiviral agents, and in particular anti-HIV agents, Central Research Institute for Chemistry of the Hungarian Academy of Sciences, Budapest, Hungary (hosts : Dr. I. Szinai, Dr. J. Sagi, Dr. J. Béres and Prof. Dr. L. Ötvös). |
| 7 July 1988 |
"Anti-HIV agents with clinical potential", Inaugural Meeting of the Medical Research Council (MRC) AIDS Directed Programme Committee, MRC Head Office, Park Crescent, London, England (hosts : Dr. M.J. Gait and Dr. M.F. Perutz, MRC Laboratory of Molecular Biology, Cambridge). |
| 7 June 1988 |
"Sulfated polysaccharides : review of their antiviral properties", Institut Choay, Paris, France (host : Dr. J. Choay, President). |
| 4 May 1988 |
"Development of new selective anti-HIV compounds", Pharmaceutical Research Center (Pharma Forschungszentrum), Bayer AG, Wuppertal, Federal Republic of Germany (hosts : Dr. G. Streissle and Prof. Dr. H.D. Schlumberger). |
| 15 April 1988 |
"New antiviral agents active against the AIDS virus", Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, California, USA (host : Prof. Dr. R.H. Shafer, Professor of Chemistry and Pharmaceutical Chemistry). |
| 25 March 1988 |
"Chemotherapy of AIDS", Departamento de Microbiologia e Immunologia, Faculdad de Farmacia y Bioquimica, Universidad de Buenos Aires (lecture delivered in Mar del Plata), Argentina (host : Prof. Dr. R.A. de Torres). |
| 4 February 1988 |
"Recent trends in antiviral chemotherapy", Institut für Immunologie und Virologie der Universität Zürich, Universitätsspital, Zürich, Switzerland (host : Prof. Dr. O. Haller). |
| 7 January 1988 |
Discussion on new leads in the development of antiviral drugs, Efamol Ltd., Woodbridge Meadows, Guildford, Surrey, England (hosts : Dr. B. Reynolds, Dr. C. Stewart and Dr. D.F. Horobin, Chief Executive Officer). |
| 6 November 1987 |
"New developments in antiviral chemotherapy", University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA (host : Prof. Dr. V. Stollar). |
| 5 November 1987 |
Discussion on the development of 2',3'-dideoxynucleoside analogues as anti-AIDS virus drugs, Science and Technology Group, Bristol-Myers Company, New York, New York, USA (host : Dr. J.A. Vida, Director of Licensing). |
| 4 November 1987 |
"New anti-HIV (human immunodeficiency virus) agents", National Institutes of Health (Building 1), Bethesda, Maryland, USA (hosts : Dr. C. Laughlin, Antiviral Substances Program Officer and Dr. G.J. Galasso, Associate Director for Extramural Affairs). |
| 3 November 1987 |
"New developments in anti-AIDS virus chemotherapy", Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA (host : Prof. Dr. W.H. Prusoff). |
| 2 November 1987 |
"New developments in antiviral chemotherapy", Pharmaceutical Research and Development Division, Bristol-Myers Company, Wallingford, Connecticut, USA (host : Dr. J.C. Martin, Associate Director of Anti-Infective Chemistry). |
| 31 August 1987 |
"Recent trends in antiviral chemotherapy", Institute of Molecular and Cell Biology, National University of Singapore, Kent Ridge, Singapore (host : Dr. Y.H. Tan, Director of the Institute of Molecular and Cell Biology). |
| 27 August 1987 |
"Clinical aspects of antiviral agents", Westmead Hospital, Sydney University Hospitals, Sydney, New South Wales, Australia (host : Dr. A.L. Cunningham, Head of the Virology Department, Institute of Clinical Pathology and Medical Research). |
| 29 July 1987 |
"Trends in the research of antiviral agents", Clinical Hospital Center (Center of Medical Sciences) of the University of Zagreb, Yugoslavia (host : Prof. Dr. G. Piljac, Director of the Center of Medical Sciences). |
| 25 July 1987 |
Planning of Bayer Centenary Conference on "A Second Century of Anti-Infective Chemotherapy", Zürich, Switzerland (host : Prof. Dr. G.G. Jackson, Keeton Professor of Medicine, The University of Illinois at Chicago). |
| 11 June 1987 |
"Antiviral drug development : new antiviral agents active against the AIDS virus", Arzneimittelsynthese, Hauptlaboratorium, BASF Aktiengesellschaft, Ludwigshafen, Federal Republic of Germany (hosts : Dr. B. Janssen, Dr. J.-U. Bliesener, and Dr. H.U. Schenck, Director). |
| 9 June 1987 |
"Nieuwe bestanddelen actief tegen het AIDS virus", Scientific Development Group, Organon, Oss, The Netherlands (hosts : Dr. H.C.J. Ottenheijm, Director of the Bio-Organic Chemistry R & D Laboratories, and Dr. K. Wiedhaup, Director of Research and Development). |
| 24 April 1987 |
"New trends in antiviral chemotherapy", R. & S. Antiinfectives, Farmitalia Carlo Erba, Milano, Italy (hosts : Dr. C. Battistini, Dr. F. Arcamone and Dr. R. Roncucci, Director of Research and Development). |
| 13-14 April 1987 |
Planning of Bayer Centenary Conference on "A Second Century of Anti-Infective Chemotherapy", Chicago, Illinois, USA (host : Prof. Dr. G.G. Jackson, Keeton Professor of Medicine, The University of Illinois at Chicago). |
| 23 February 1987 |
"New targets for new antiviral agents", Centre International de Recherches Dermatologiques (CIRD), Sophia Antipolis, Valbonne Cédex, France (hosts : Dr. J.C. Jamoulle, Dr. B. Shroot and Prof. Dr. H. Schaefer, Director CIRD). |
| 27 January 1987 |
"New developments in antiviral chemotherapy", Hoechst Pharma-Synthese, Hoechst Aktiengesellschaft, Frankfurt am Main, Federal Republic of Germany (hosts : Dr. M. Rösner, Prof. Dr. R. Geiger and Prof. Dr. W. Bartmann, Director, Hoechst Pharma-Synthese). |
| 21 January 1987 |
"Review of the current research on antiviral agents", Pasteur Vaccins, Paris, France (Hosts : Dr. M. Girard, Scientific Director, and Mrs. M.-J. Lecomte, Chairman of Pasteur Vaccins). |
| 17 December 1986 |
Discussion on the development of new phosphonate derivatives of purine and pyrimidine nucleosides, Science and Technology Group, Bristol-Myers Company, New York, New York, USA (hosts : Dr. J.A. Vida, Director of Licensing, and Dr. G. Vita, President of Bristol-Myers Research and Development). |
| 15 December 1986 |
"New developments in antiviral agents : (S)-HPMPA analogues and 2',3'-dideoxynucleoside analogues", Pharmaceutical Research and Development Division, BristolMyers Company, Wallingford, Connecticut, USA (host : Dr. J.C. Martin, Associate Director of Anti-Infective Chemistry). |
| 11 December 1986 |
"New developments in antiviral chemotherapy", Gemeinsames Chemisches und Biologisches Kolloquium, Fachbereich Biologie/ Chemie, Osnabrück, Federal Republic of Germany (host : Prof. Dr. F. Seela, Laboratorium für Organische und Bioorganische Chemie). |
| 15 September 1986 |
Discussion on the ophthalmic use of bromovinyldeoxyuridine, Dr. Mann Pharma, Berlin-West, Federal Republic of Germany (hosts : Dr. O. Riel, Marketing Director, and Dr. E. Schwalbe-Riel, Managing Director). |
| 14 May 1986 |
"New developments in the search for selective antiviral agents", Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA (host : Prof. Dr. W.H. Prusoff). |
| 13 May 1986 |
"Recent developments in antiviral chemotherapy", Ortho Pharmaceutical (Canada) Ltd., Don Mills, Toronto, Ontario, Canada (host : Dr. D. Ilse, Director, Pharmaceutical Research Department). |
| 12 May 1986 |
Discussion on the structure-activity relationship of 5-substituted 2'-deoxyuridines, Department of Physiological Sciences, College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (host: Prof. Dr. V.S. Gupta). |
| 24 April 1986 |
"Recent developments in antiviral chemotherapy", jointly organized by the Czechoslovak Chemical and Medical Societies, Prague, Czechoslovakia (hosts : Dr. K. Sebesta, Director of the Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, and Prof. Dr. B. Korych, Faculty of Medicine, Charles' University). |
| 11 April 1986 |
"New developments in antiviral chemotherapy", Department of Experimental Oncology and Virology, Roche Research Center, Hoffmann-La Roche Inc., Nutley, New Jersey, USA (host : Dr. I.S. Sim, Head of Antiviral Chemotherapy). |
| 14 March 1986 |
"Recent developments in antiviral chemotherapy, particularly towards retrovirus infections", Sandoz Forschungsinstitut, Vienna, Austria (host : Dr. B. Rosenwirth). |
| 5 March 1986 |
Discussion of the therapeutic use of phosphonylmethoxyalkyl derivatives of adenosine as antiviral agents, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Science, Prague, Czechoslovakia (Host : Dr. K. Sebesta, Director of the Institute of Organic Chemistry and Biochemistry). |
| 11 February 1986 |
"Broad-spectrum anti-DNA virus activity of acyclic adenosine phosphonate analogues", Pharmaceutical Research and Development Division, Bristol-Myers Company, Syracuse, New York, USA (host : Dr. C. McLaren). |
| 10 February 1986 |
Discussion on the development of new adenosine analogues (phosphonylmethoxyalkyl derivatives) as antiviral agents, Science and Technology Group, Bristol-Myers Company, New York, New York, USA (hosts: Dr. J.A. Vida, Director of Licensing, and Dr. G. Vita, President of Bristol-Myers Research and Development). |
| 21 January 1986 |
Discussion on the molecular and pharmacological aspects of protein-nucleic acid interactions (with Prof. Dr. J.W. Lown, Prof. Dr. J.-L. Imbach, Dr. O. Kennard and Prof. Dr. C. Paoletti), Laboratoire de Pharmacologie Moléculaire, Institut Gustave-Roussy, Villejuif, France (host : Prof. Dr. C. Paoletti). |
| 16 January 1986 |
"Perspectives d'avenir sur les antiviraux", Groupe d'Etude et de Recherche sur l'Herpès (G.E.R.H.), Paris, France (hôtes : Dr. B. Audeval, Secrétaire, et Prof. Dr. B. de Thé, Président du Groupe d'Etude et de Recherche sur l'Herpès). |
| 3 October 1985 |
Discussion on the world-wide industrial development of bromovinyldeoxyuridine, VEB-Berlin Chemie, Humboldt-Universität, Akademie der Wissenschaften der DDR, Berlin, DDR (hosts : Dr. G. Hüttel, Prof. Dr. H.A. Rosenthal and Prof. Dr. P. Langen). |
| 26 September 1985 |
"Recent developments in antiviral chemotherapy", Infectious Disease Division, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts, USA (host : Prof. Dr. C. Crumpacker). |
| 25 September 1985 |
"Recent developments in antiviral chemotherapy", Sterling-Winthrop Research Institute, Rensselaer, New York, USA (hosts : Dr. G. Diana and Dr. M.J. Otto). |
| 23 September 1985 |
"Recent developments in antiviral chemotherapy", Molecular Biology Seminar Series, The University of Kansas, Lawrence, Kansas, USA (host : Prof. Dr. M.P. Mertes). |
| 20 June 1985 |
Discussion on the role of S-adenosylhomocysteine hydrolase in the antiviral activity of nucleoside analogues, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Science, Prague, Czechoslovakia (host: Dr. A. Holý). |
| 6 June 1985 |
Discussion on the clinical development of antiviral agents, Science and Technology Group, Bristol-Myers Company, New York, New York, USA (hosts: Dr. J.A. Vida, Director of Licensing, and Dr. G. Vita, President of Bristol-Myers Research and Development). |
| 5 June 1985 |
"New trends in antiviral chemotherapy", Pharmaceutical Research and Development Division, Bristol-Myers Company, Syracuse, New York, USA (host : Dr. C. McLaren). |
| 4 June 1985 |
Discussion on assay systems for the evaluation of antiviral agents against high hazard viral infections, US Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, Maryland, USA (host : Dr. P.G. Canonico, Chief, Department of Antiviral Studies). |
| 28 March 1985 |
"New developments in antiviral chemotherapy", Wissenschaftliche Abteilung, Robugen GmbH, Pharmazeutische Fabrik, Esslingen/Neckar, Federal Republic of Germany (hosts : Dr. E. Mauz and Dr. B. Hempel). |
| 26 March 1985 |
"Inhibitors of reverse transcriptase and retrovirus replication", Paul-Ehrlich-Institut, Frankfurt/Main, Federal Republic of Germany (host : Prof. Dr. H.D. Brede, President of the Paul-Ehrlich Institute). |
| 25 March 1985 |
"Strategies in designing antiherpetic drugs", Gustav-Embden-Zentrum der Biologischen Chemie, Klinikum der Johann Wolfgang Goethe Universität, Frankfurt/Main, Federal Republic of Germany (host : Prof. Dr. P. Chandra). |
| 27 February 1985 |
"Recent developments on antiviral agents", Institut für Immunologie und Onkologie, Bayer AG Pharma-Forschungszentrum, Wuppertal, Federal Republic of Germany (hosts : Dr. G. Streissle and Prof. Dr. H.D. Schlumberger). |
| 15 January 1985 |
"Antiviral potential of pyrimidine and purine carbocyclic nucleoside analogues", Glaxo Group Research Ltd., Greenford, Middlesex, England (host : Dr. J.M. Cameron). |
| 13 December 1984 |
Round Table Discussion on Antiviral Potentials of Bromovinyldeoxyuridine, Merz & Co. GmbH, Frankfurt am Main, Federal Republic of Germany (host : Dr. L.H. Bonacker, Vice-President). |
| 12 December 1984 |
"Recent developments in antiviral therapy", Robert Koch-Institut, Berlin, Federal Republic of Germany (host : Prof. Dr. H. Diringer). |
| 11 December 1984 |
"Recent developments on antiherpetic drugs", Robert Koch Höhrsahl, Bereich Medizin (Charité) der Humboldt-Universität, Berlin, D.D.R. (host : Prof. Dr. H.A. Rosenthal). |
| 9 October 1984 |
"Recent developments in antiviral chemotherapy", Université des Sciences et Techniques du Languedoc, Montpellier, France (host : Prof. Dr. B. Lebleu). |
| 28 September 1984 |
"Antiviral potentials of 5-chloroethyldeoxyuridine in comparison with 5-bromovinyldeoxyuridine", Sandoz Forschungsinstitut, Vienna, Austria (hosts : Dr. B. Rosenwirth and Dr. H. Bachmayer, Head of the Department of Virology). |
| 14 September 1984 |
"Targets for the development of new antiviral agents", Toyo Jozo Research Laboratories, Mifuku Ohito-cho, Togata-Gun, Shizuoka-ken, Japan (hosts : Dr. K. Fujimoto, Director New Business Development, and Dr. J. Murase, Director Medicinal Research Laboratories). |
| 1 August 1984 |
"Targets for antiviral and antitumour agents", Department of Biochemical Pharmacology, Institute of Cancer Research, Belmont, Sutton, Surrey, England (host : Prof. Dr. K. Harrap, Department Head). |
| 17 April 1984 |
"Targets for antiviral agents", The Upjohn Company, Kalamazoo, Michigan, USA (host : Dr. H.E. Renis). |
| 16 April 1984 |
"Potency and selectivity of bromovinyldeoxyuridine as an anti-herpes agent", Marjorie B. Kovler Viral Oncology Laboratories, Committee on Virology, The University of Chicago, Chicago, Illinois, USA (host : Prof. Dr. B. Roizman, Chairman). |
| 6 April 1984 |
"Targets for the antiviral and antitumor action of nucleoside analogs", Smith Kline and French Laboratories, Research and Development, Philadelphia, Pennsylvania, USA (host : Dr. H.S. Allaudeen). |
| 5 April 1984 |
"Promises and pitfalls of antiherpes drugs", Department of Microbiology, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania, USA (host: Prof. Dr. F. Rapp, Chairman). |
| 4 April 1984 |
"Recent developments on bromovinyldeoxyuridine, a selective antiherpes agent", Department of Pharmacology and Experimental Therapeutics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (host : Prof. Dr. P.S. Lietman). |
| 3 April 1984 |
"Promises and failures of antiviral chemotherapy", Department of Microbiology, School of Medicine, New York University, New York, USA (host : Prof. Dr. R.J. Klein). |
| 2 April 1984 |
Round Table Discussion on New Leads in the Development of Antiviral Agents, Schering Corporation, Bloomfield, New Jersey, USA (host : Dr. G.H. Miller, Director of Antibiotic Screening and Evaluation). |
| 23 February 1984 |
"Therapeutic potentials of bromovinyldeoxyuridine", Institut für Virologie der Universität zu Köln, Köln, Federal Republic of Germany (host : Prof. Dr. H.J. Eggers, Director). |
| 4 October 1983 |
"New trends in antiviral chemotherapy", Instituto de Quimica Medica, Consejo Superior de Investigaciones Cientificas, Madrid, Spain (host : Dr. F.G. De las Heras). |
| 30 August 1983 |
Round Table Discussion on the Use of Animal Models in the Evaluation of Antiherpes Agents, Sandoz Forschungsinstitut, Vienna, Austria (host : Dr. H. Bachmayer, Head of the Department of Virology). |
| 29 March 1983 |
"Therapeutic potentials of bromovinyldeoxyuridine", Hutzel Hospital, School of Medicine, Wayne State University, Detroit, Michigan, USA (host : Prof. Dr. A.M. Lerner, Chief). |
| 28 March 1983 |
"Antiviral activity of 5-substituted 2'-deoxyuridines", College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA (hosts : Prof. Dr. L.B. Townsend, Chairman, and Prof. Dr. J.C. Drach). |
| 25 March 1983 |
"Therapeutic potentials of bromovinyldeoxyuridine", Children's Hospital Medical Center, University of Washington, Seattle, Washington, USA (host : Prof. Dr. L. Corey). |
| 22 March 1983 |
"Strategies in the design of antiviral agents", Smith Kline and French Laboratories, Research and Development, Philadelphia, Pennsylvania, USA (host : Dr. H.S. Allaudeen). |
| 21 March 1983 |
"Strategies in the design of antiviral agents", National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA (host : Dr. G.L. Cantoni, Chief, Laboratory of General and Comparative Biochemistry). |
| 8 February 1983 |
"Targets for the design of antiviral drugs", Pfizer Central Research, Sandwich, Kent, England (host : Dr. W.D. Butt, Director). |
| 10 December 1982 |
"Strategies in the design of antiviral agents", Southern Research Institute, Birmingham, Alabama, USA (host : Dr. J.A. Montgomery, Senior Vice-President). |
| 9 December 1982 |
"Development of inhibitors of herpes simplex virus replication", Department of Microbiology, The University of Alabama in Birmingham, Birmingham, Alabama, USA (host : Prof. Dr. R.J. Whitley). |
| 8 December 1982 |
"Nucleoside and polynucleotide analogues as antiviral agents", Department of Microbiology, The University of Texas Medical Branch, Galveston, Texas, USA (host : Prof. Dr. S. Baron, Chairperson). |
| 7 December 1982 |
"Selective antiherpes agents", Wadley Institutes of Molecular Medicine, Dallas, Texas, USA (host : Dr. N.O. Hill, President). |
| 7 December 1982 |
"Selective antiherpes agents", Department of Biological Sciences, North Texas State University, Denton, Texas, USA (host : Dr. Y.C. Chen). |
| 6 December 1982 |
"Strategies for the design of antiviral drugs", Research and Development Microbiology, Alcon Laboratories, Fort Worth, Texas, USA (host : Dr. B.A. Schlech, Director). |
| 6 December 1982 |
"Selective antiherpes agents", Department of Microbiology and Immunology, North Texas State University, Fort Worth, Texas, USA (host : Prof. Dr. E.F. Harris, Chairperson). |
| 6 December 1982 |
"Strategies for the design of antiviral drugs", Texas College of Osteopathic Medicine, North Texas State University, Fort Worth, Texas, USA (host : Prof. Dr. L.B. Allen). |
| 3 December 1982 |
"Antiviral potentials of bromovinyldeoxyuridine (BVDU)", Department of Pediatrics, UCLA School of Medicine, University of California, Los Angeles, California, USA (host : Prof. Dr. Y. Bryson). |
| 30 November 1982 |
"Recent developments in antiviral chemotherapy", Tohoku University School of Medicine, Sendai, Japan (host : Prof. Dr. N. Ishida). |
| 29 November 1982 |
"Recent developments in antiherpes chemotherapy", Fukushima Medical College, Fukushima, Japan (host : Prof. Dr. S. Shigeta). |
| 27 November 1982 |
"Design of nucleoside analogues as selective antiviral agents", Aichi Cancer Center Research Institute, Chikusa-ku, Nagoya, Japan (host : Dr. K. Ono). |
| 22 November 1982 |
"Recent progress in antiviral chemotherapy", Department of Microbiology, School of Medicine, Chiba University, Inohana, Chiba, Japan (host : Prof. Dr. T. Kuwata). |
| 22 November 1982 |
"Selective antiherpes agents", Yamasa Shoyu Co. Research Laboratories, Araoicho, Choshi, Chiba, Japan (hosts : Dr. H. Machida and Dr. A. Kuninaka). |
| 14 September 1982 |
"Strategies in the design of antiviral drugs", Roche Research Lecture Programme, Roche Products Limited, Welwyn Garden City, England (hosts : Dr. R.W. Lambert, Dr. M.J. Hall and Dr. C.H. Hassall). |
| 1 September 1982 |
"Therapeutic potentials of BVDU [(E)-5-(2-bromovinyl)-2'-deoxyuridine] in the treatment of herpesvirus infections", Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA (host : Dr. E.R. Kern). |
| 30 August 1982 |
"Antiviral drugs : recent developments", Department of Animal, Dairy and Veterinary Sciences, College of Agriculture, Utah State University, Logan, Utah, USA (host : Prof. Dr. R.W. Sidwell). |
| 26 August 1982 |
"Antiviral potential of bromovinyldeoxyuridine (BVDU) and other 5-substituted pyrimidine nucleoside analogues", Alberta Heritage Foundation for Medical Research, The University of Alberta, Edmonton, Alberta, Canada (host : Prof. Dr. M.J. Robins). |
| 24 August 1982 |
"Therapeutic potentials of BVDU [(E)-5-(2-bromovinyl)-2'-deoxyuridine] in the treatment of herpesvirus infections", Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada (host : Dr. S.L. Sacks). |
| 4 August 1982 |
"Selective antiherpes drugs : therapeutic potentials for the treatment of herpes simplex and varicella zoster virus infections", Behringwerke AG, Marburg, Federal Republic of Germany (hosts : Dr. J. Hilfenhaus and Dr. R.F. Mauler). |
| 12 May 1982 |
"Antiviral potentials of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU)", Searle Research and Development, G.D. Searle, High Wycombe, Bucks, England (host: Dr. B.M. Richards). |
| 4 November 1981 |
"Therapeutic potentials of antiherpetic drugs", Forschungszentrum für Molekularbiologie und Medizin, Akademie der Wissenschaften der DDR, Berlin-Buch, D.D.R. (hosts : Prof. Dr. P. Langen and Prof. Dr. W. Zschiesche). |
| 2 November 1981 |
"Antiviral potentials of bromovinyldeoxyuridine", Bereich Medizin (Charité) der HumboldtUniversität, Berlin, D.D.R. (host : Prof. Dr. H.A. Rosenthal). |
| 8 September 1981 |
"New developments in antiviral research", Institute of Virology, Natural Environment Research Council, Oxford, England (hosts : Dr. D.C. Kelly and Dr. T.W. Tinsley). |
| 26 August 1981 |
"Antiviral potentials of E-5-(2-halogenovinyl)pyrimidine nucleosides", Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA (hosts : Dr. H.S. Allaudeen and Prof. Dr. W.H. Prusoff). |
| 24 August 1981 |
"Antiviral potentials of bromovinyldeoxyuridine", Searle Research and Development (G.D. Searle & Co.), Chicago, Illinois, USA (hosts : Prof. Dr. D. Azarnoff and Dr. H. Schoepke). |
| 21 August 1981 |
"Strategies in the design of antiviral drugs", Faculty of Medicine, The University of Alberta, Edmonton, Alberta, Canada (hosts : Prof. Dr. M.J. Robins and Prof. Dr. A.R.P. Paterson). |
| 18 August 1981 |
"Selective antiviral drugs", Syntex Research, Palo Alto (Dr. D.A. Eppstein), and Stanford University School of Medicine, Stanford, California, USA (host : Prof. Dr. T.C. Merigan). |
| 29 June 1981 |
"Recent advances in antiviral chemotherapy", Division of Infectious Diseases, Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts, USA (host : Prof. Dr. C. Crumpacker). |
| 3-4 June 1981 |
"BVDU, E-5-(2-bromovinyl)-2'-deoxyuridine, review : |
| - Antiviral activity in vitro |
| - Antiviral activity in vivo |
| - Mechanism of action |
| - Pharmacology and toxicology |
| - Clinical efficacy", |
| Searle Research and Development (G.D. Searle & Co.), Sophia Antipolis, France (host : Dr. A.J. Hale). |
| 15 May 1981 |
"New antiherpesvirus agents", Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, |
| Maryland, USA (host : Prof. Dr. P.S. Lietman). |
| 14 May 1981 |
"Selective antiviral drugs with therapeutic potential", The Wellcome Research Laboratories, Burroughs Wellcome Co., Research Triangle Park, North Carolina, USA (host : Dr. L. Beacham). |
| 11 May 1981 |
"Selective antiviral drugs", National Institutes of Health (NIH), Bethesda, Maryland, USA (host : Dr. P.F. Torrence). |
| 30 April 1981 |
"New developments in antiviral chemotherapy", Department of Pathology, Addenbrooke's Hospital, University of Cambridge, England (hosts : Dr. H.J. Field & Prof. Dr. P. Wildy). |
| 29 April 1981 |
"Recent developments in antiviral chemotherapy", Department of Chemistry, The University of Birmingham, England (hosts : Dr. R.T. Walker & Prof. Dr. A.S. Jones). |
| 10 April 1981 |
"Nieuwe ontwikkelingen op het gebied van antivirale middelen", Medische Microbiologie, Rijksuniversiteit Groningen, The Netherlands (host : Prof. Dr. J.B. Wilterdink). |
| 23 February 1981 |
"Bromovinyldeoxyuridine and other selective antiviral drugs", Institut für Pharmazie und Lebensmittelchemie der Friedrich-Alexander Universität, Erlangen-Nürnberg, Federal Republic of Germany (host : Prof. Dr. O Dann). |
| 29 January 1981 |
"Antiviral chemotherapy : state of the art", Forschung Grünenthal GmbH, Aachen, Federal Republic of Germany (hosts : Dr. P. Jacobi & Dr. R. Hörhammer). |
| 5 November 1980 |
"New developments in antiviral chemotherapy", Wissenschaftliche Abteilung, Robugen GmbH, Pharmazeutische Fabrik, Esslingen/Neckar, Federal Republic of Germany (hosts : Dr. E. Mauz & Dr. B. Hempel). |
| 26 June 1980 |
"Perspectives of nucleoside analogues in the chemotherapy of viral diseases", Central Research Institute for Chemistry of the Hungarian Academy of Sciences, Budapest, Hungary (hosts : Prof. Dr. L. Ötvös & Dr. J. Sagi). |
| 11 March 1980 |
"E-5-(2-Bromovinyl)-2'-deoxyuridine : a potent and selective anti-herpes agent", Beecham Pharmaceuticals (Chemotherapeutic Research Centre), Brockham Park, Betchworth, Surrey, England (host : Dr. D. Planterose). |
| 11 October 1979 |
"Anti-herpes chemotherapy", Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut,USA (host : Prof. Dr. W.H. Prusoff). |
| 10 October 1979 |
"New anti-herpes agents", Memorial Sloan-Kettering Cancer Center, New York, N.Y., USA (host : Prof. Dr. J.J. Fox). |
| 11 June 1979 |
"Reverse transcriptase inhibitors", Institut für Pharmazie und Lebensmittelchemie der Friedrich-Alexander Universität, Erlangen-Nürnberg, Federal Republic of Germany (host : Prof. Dr. O. Dann). |
| 29 March 1979 |
"Antiviral chemotherapy : selective anti-herpes agents", Department of Antiviral Chemotherapy, Research and Development Laboratories, Astra Läkemedel AB, Södertälje, Sweden (host : Dr. E. Helgstrand). |
| 28 June 1978 |
"Development of new antivirals", Experimental Station, Central Research & Development Department, E.I. du Pont de Nemours & Company, Wilmington, Delaware, USA (host : Dr. R.Z. Lockart Jr). |
| 15 October 1976 |
"Polynucleotides as inducers of interferon", University of Cincinnati, Cincinnati, Ohio, USA (host : Prof. Dr. A.M. Bobst). |
| 8 October 1976 |
"Polynucleotides as inducers of interferon", Tufts University School of Medicine, Boston, Massachusetts, USA (host: Prof. Dr. B.D. Stollar). |
| 28 November 1975 |
"Mécanisme d'induction de l'interféron par des polynucléotides synthétiques", Institut National de la Recherche Agronomique (Station de Recherches de Virologie et d'Immunologie), Thiverval-Grignon, France (host : Dr. R. Scherrer). |
| 23 October 1975 |
"Les polynucléotides synthétiques en tant qu'inducteurs d'interféron et/ou inhibiteurs de la rétrotranscriptase", Institut de Cancérologie et d'Immunogénétique (ICIG), Villejuif, France (host : Prof. Dr. C. Jasmin). |
| 10 September 1975 |
"Interferon induction by RNAs, double- and triple-stranded", Roswell Park Memorial Institute, Buffalo, New York, USA (host : Prof. Dr. W.A. Carter). |
| 8 September 1975 |
"Antiviral activity of novel nucleoside analogs", National Institutes of Health (NIH), Bethesda, Maryland, USA (host : Dr. P.F. Torrence). |
| 4 September 1975 |
"Synthetic polynucleotides as inducers of interferon and/or inhibitors of reverse transcriptase", Molecular Biology Department, Miles Laboratories, Elkhart, Indiana, USA (host : Dr. B. Janik). |
| 5 June 1975 |
"Synthetische polynucleotiden als inductoren van interferon en/of inhibitoren van de reverse transcriptase", Universiteit van Nijmegen, The Netherlands (host : Dr. H.P.J. Bloemers). |
| 4 April 1975 |
"Interactions among polynucleotides as monitored by interferon induction", National Institutes of Health (NIH), Bethesda, Maryland, USA (hosts : Dr. P.F. Torrence & Dr. B. Witkop). |
| 22 June 1972 |
"The mechanism of interferon induction by synthetic double-stranded polynucleotides", Institut du Radium, Fondation Curie, Orsay, France (host : Dr. E. De Maeyer). |
| 23 May 1972 |
"Recent studies on mechanism of induction and action of interferon", Czechoslovak Academy of Sciences, Institute of Virology, Bratislava, Czechoslovakia (host : Dr. L. Borecky). |
| 19 May 1972 |
"Biochemical aspects of the induction and action of interferon", Polish Academy of Sciences, Institute of Biochemistry and Biophysics, Warsaw, Poland (host : Prof. Dr. D. Shugar). |
| 18 May 1972 |
"New perspectives in the clinical application of interferon and interferon inducers", The M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland (host: Prof. Dr. D. Shugar). |
| 5 November 1970 |
"Mechanism of interferon induction by synthetic polynucleotides". Experimental Station, Central Research & Development Department, E.I. du Pont de Nemours & Company, Wilmington, Delaware, USA (host : Dr. R.Z. Lockart, Jr.). |
| 3 November 1970 |
"Structural requirements of synthetic polynucleotides for induction of interferon", The Johns Hopkins University Medical School, Baltimore, Maryland, USA (hosts: Dr. W.A. Carter and Prof. Dr. P.O.P. Ts'o). |
| 2 November 1970 |
"Interferon inducers", National Institutes of Health, Bethesda, Maryland, USA (host : Dr. R.M. Friedman). |
|
Lectures at Foreign Universities and Research Institutes |
| July 2014 |
“Virology in the last 4 decades: Breakthroughs and Benefits” (Conference in honor of A.D.M.E. Osterhaus), WTC (World Trade Center), Rotterdam, The Netherlands, 2 July 2014. |
| “Antiviral treatment of chronic viral diseases” (invited lecture). |
| December 2013 |
International Symposium on Prevention and Control of Viral Diseases, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Korea, 12 December 2013. |
| “Current antiviral drug development” (plenary lecture). |
| November 2013 |
The 4th CPA-RSC Symposium on Medicinal Chemistry: Epigenetics as Targets for Drug Discovery [hosts: Chinese Pharmaceutical Association (CPA) and Royal Society of Chemistry (RSC)], Jinan, P.R. China, 2-3 November 2013. |
| “Current antiviral drug development” (invited lecture). |
| September 2013 |
15th Blue Danube Symposium on Heterocyclic Chemistry, Olomouc, Czech Republic, 1-5 September 2013. |
| “The acyclic nucleoside phosphonates (ANPs): Antonín Holý’s legacy” (invited lecture). |
| May 2013 |
26th International Conference on Antiviral Research (ICAR), San Francisco, CA, USA, 11-15 May 2013. |
| “Personal Note on the Contribution and Legacy of Tony Holý”. Symposium on Legacy of Tony Holý: Nucleotides in the treatment and prevention of chronic viral infections (invited lecture). |
| January 2013 |
Fourth Christophe Mérieux Conference on “Trends in Virology”, Fondation Mérieux Conference Center, Les Pensières, Veyrier du Lac, France, 27-29 January 2013. |
| “Drug combination therapy for HIV infections (AIDS)” (invited lecture). |
| October 2012 |
110th Autumn Meeting of the Korean Chemical Society, Busan, South Korea, 18 October 2012. |
| “A 40 year-journey in search of selective antiviral chemotherapy” (invited lecture). |
| September 2012 |
15th Annual Meeting of the European Society for Clinical Virology (ESCV), Madrid, Spain, 4-6 September 2012. |
| “New antivirals: tenofovir” (keynote lecture) (scheduled). |
| June 2012 |
Participation Wilton Park Meeting “The new era on HIV/AIDS treatment and prevention: science, implementation and finance”, Geneva (Jiva Hill Park Hotel, Crozet, France), 27-28 June 2012. |
| April 2012 |
International Society for Antiviral Research and Japanese Association for Antiviral Therapy, Twenty-fifth International Conference on Antiviral Research (ICAR), Sapporo, Japan, 16-19 April 2012. |
| “Successes and failures in antiviral drug development: a personal account”, 25th Anniversary Lecture (invited). |
| March 2012 |
Symposium on Viruses and Antiviral Therapy (in honor of Dr. Hugh J. Field), Queen’s College, Cambridge, United Kingdom, 23 March 2012. |
| “Development of selective anti-herpesvirus agents” (invited lecture). |
| January 2012 |
International Research Training Group (IRTG). International Meeting on “HIV and associated infectious diseases” (organized by the students of Würzburg), Rudolf Virchow Center, University of Würzburg, Würzburg, Germany, 19-20 January 2012. |
| “Therapy and prophylaxis of HIV infection” (invited lecture). |
| September 2011 |
International Meeting “Chemokines and Chemokine Receptors in Cancer: Role of Microenvironment”, Istituto Nazionale Tumori, Fondazione Pascale, Naples, Italy, 26-27 September 2011. |
| -Chairperson of Session “Chemokine and Chemokine Receptors Moduluation”. |
| -Invited lecture on “CXCR4 antagonist AMD3100”. |
| September 2011 |
XV International Congress of Virology, Sapporo, Hokkaido, Japan, 11-16 September 2011. |
| Convener, Antiviral Drugs. |
| November 2010 |
Antivirals Congress, Celebrating 30 Years of the Journal Antiviral Research, Amsterdam, The Netherlands, 7-9 November 2010. |
| -Chairman of the Congress |
| -Session Chair of the Opening Session & Plenary Session 1 – Setting the scene (planned). |
| -Anniversary lecture “A thirty year journey with the journal Antiviral Research: how it started and evolved” (invited lecture) (read by Floris de Hon). |
| September 2010 |
Dr. Paul Janssen Award for Biomedical Research, Janssen Pharmaceutica, Beerse, Belgium, 9 September 2010. |
| Press Conference, Keynote address, Recollection Dr. Paul Janssen’s legacy. |
| September 2010 |
Dr. Paul Janssen Award for Biomedical Research, Ronald Reagan Building, Washington DC, USA, 7, 8 September 2010. |
| Interview, Acceptance speech, Panel discussion. |
| August-September 2010 |
International Round Table (IRT) on Nucleosides, Nucleotides and Nucleic |
| Acids, Lyon, France, 29 August-3 September 2010. |
| “The paths to the discovery of antivirally active nucleoside and nucleotide analogues” (Montgomery Award Lecture). |
| June 2010 |
Third International Meeting on Pharmacy and Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul, Turkey, 9-12 June 2010. |
| “The antiviral drug era: Half a century after the synthesis of the first antiviral drug” [invited plenary (inaugural) lecture]. |
| April-May 2010 |
Centennial Retrovirus Meeting, Institute of Molecular Genetics, Prague, Czech Republic, 29 April-4 May 2010. |
| -“Prospects of anti-HIV therapy” (invited lecture). |
| -Chairman of Session “Anti-viral strategies: drugs and vaccines” (invited). |
| April 2010 |
International Liver Congress 2010, 45th Annual Meeting of the European Association for the Study of Liver, Vienna, Austria, 14-18 April 2010. |
| “Tenofovir disoproxil fumarate (TDF) in the treatment of chronic hepatitis B” (lecture prepared; presented on 17 April 2010 by Dr. Norbert Bischofberger (Senior Vice President and Chief Scientific Officer, Gilead Sciences). |
| December 2009 |
British Pharmacological Society Winter Meeting (Symposium on “Chemokine antagonists as therapeutic agents”), Queen Elizabeth II Conference Centre, London, United Kingdom, 15-17 December 2009. |
| November 2009 |
23rd Annual Meeting of the Japanese Society for AIDS Research, Nagoya, Japan, 26-28 November 2009. |
| “State of the art on anti-HIV chemotherapy” (invited keynote lecture) (host: Takashi Okamoto, Professor and Chairman, Department of Molecular and Cellular Biology, Nagoya City University Graduate School of Medical Sciences). |
| September 2009 |
Twelfth Annual ESCV (European Society for Clinical Virology) Meeting, Istanbul, Turkey, 27-30 September 2009. |
| “Antiviral activity of acyclic and cyclic nucleoside phosphonates” (invited conference lecture). |
| August-September 2009 |
NITD Conference on Dengue 2009, Novartis Institute for Tropical Diseases, |
| Manila, Edsa Shangri-La Hotel, The Philippines, 31 August-4 September 2009. |
| “Dengue in the perspective of other global virus infections. Anno 2009” (keynote plenary lecture, invited). |
| March 2009 |
First UK Drug Discovery Consortium (UK DDC) Symposium “21st Century Drug Discovery: a New Approach”, The Royal College of Physicians, Regent’s Park, London, United Kingdom, 11 March 2009. |
| “Discovery of the acyclic nucleoside phosphonates cidofovir, adefovir and tenofovir as antiviral drugs” (keynote lecture). |
| October 2008 |
Annual Meeting of the Dutch Pharmacological Society, Dutch Medicine Days, Lunteren, The Netherlands, 7-9 October 2008. |
| “The path to drug discovery: the AMD 3100 story” (2008 Ariëns Lecture, 7 October 2008, invited). |
| September 2008 |
XXI. Biochemický sjezd (21st Biochemistry Congress), České Budéjovice, Czech Republic, 14-17 September 2008 |
| “Antiviral activity of acyclic and cyclic nucleoside phosphonates” (invited lecture). |
| August 2008 |
Sixth European Conference of European Society for Infectious Diseases in Obstestrics and Gynaecology, Leuven, Belgium, 28-31 August 2008. |
| “Present and future of antiretrovirals” (invited lecture). |
| August 2008 |
Fourteenth International Congress of Virology, Istanbul, Turkey, 10-15 August 2008. |
| -“Antiviral drugs with special emphasis on anti-HIV compounds” (invited lecture). |
| -Chairman of Symposium on Antiviral Drugs (invited). |
| July 2008 |
International Conference “Drug Design and Discovery for Developing Countries” [International Centre for Science and High Technology (ICS), United Nations Industrial Development Organization (UNIDO)], Trieste, Italy, 3-5 July 2008. |
| “Antiviral drugs for AIDS: Current state of the art” (keynote lecture, invited). |
| June 2008 |
Sixth International Conference on HHV-6 & 7, Baltimore, Maryland, USA, 19 June-22 June 2008. |
| -Chairman of session on Treatment(s) (invited). |
| -Participant of panel discussion on Treatment(s) (invited). |
| June 2008 |
The 4th SINO-US Chemistry Professors Conference (The 4th SINO-US Symposium on Organic Chemsitry, Peking University Health Science Center, Peking University, Beijing, P.R. China, 12-13 June 2008. |
| “Antiviral activity of acyclic and cyclic nucleoside phosphonates” (invited lecture). |
| May 2008 |
Fifteenth International Symposium on HIV and Emerging Infectious Diseases (15th ISHEID), Toulon, France, 28-30 May 2008. |
| -Pre-exposure prophylaxis for HIV infection (invited lecture). |
| -Chairman Poster Discussion session. |
| May 2008 |
European Patent Forum 2008 and European Inventor of the Year 2008 (organized by the European Patent Office (EPO)), Grand Hotel Union, Ljubljana, Slovenia, 6-7 May 2008. |
| Participant (invited). |
| April 2008 |
Twenty-first International Conference on Antiviral Research (ICAR), Montreal, Quebec, Canada, 13-17 April 2008. |
| -Editorial Board Meeting of Antiviral Research. |
| -Program Committee, Nomination Committee, Finance Committee, Publications Committee and Conference Committee meetings of ISAR. |
| February 2008 |
First International Conference on Drug Design and Discovery, Dubai, United Arab Emirates (UAE), 4-7 February 2008. |
| -Organizing Secretary of the section on Drugs for Infectious Diseases |
| -“Current drugs for the treatment of HIV infection (AIDS). Role of acyclic nucleoside phosphonates” (invited plenary lecture). |
| -Chairman of Section on New Drugs for Infectious Diseases (invited). |
| October-November 2007 |
Eighth International Symposium on NeuroVirology, 30 October-2 November |
| 2007, San Diego, California, USA. |
| “In search of antivirals for the treatment of neurovirus infections” (invited plenary lecture). |
| June 2007 |
TRIoH Fourth General Assembly and Open Symposium. Targeting Replication and Integration of HIV (in collaboration with the Belgian Society of Biochemistry and Molecular Biology), Convent van Chièvres, Groot Begijnhof, Leuven, Belgium, 11-12 June 2007. |
| “Acyclic nucleoside phosphonates as antiviral agents” (invited lecture). |
| April-May 2007 |
Twentieth International Conference on Antiviral Research (ICAR), Palm Springs, California, USA, 29 April-3 May 2007.. |
| -Editorial Board Meeting of Antiviral Research. |
| -Directory Board Meeting of the International Society of Antiviral Research (ISAR). |
| -Program Committee, Nomination Committee, Finance Committee, Publications Committee and Conference Committee meetings of ISAR. |
| November 2006 |
Symposium on “AIDS in the Third World”, Koninklijke Academie voor Geneeskunde van België (Royal Academy of Medicine of Belgium), Paleis der Academiën (Palace of the Academics), Brussels, Belgium, 25 November 2006. |
| -Convener of the Symposium (with Peter Piot as co-convener). |
| -“Anti-HIV agents” (invited lecture). |
| October 2006 |
Medicinal Chemistry in the 21st Century (Organic Chemistry Division of the Portuguese Chemical Society, Faculty of Pharmacy), Lisbon, Portugal, 13-14 October 2006. |
| “Acyclic nucleoside phosphonates: past, present and future” (invited plenary lecture”. |
| October 2006 |
EVER (European Association for Vision and Eye Research) meeting, Vilamoura, Portugal, 4-7 October 2006. |
| AER (Association for Eye Research) Award Lecture on “Antivirals for viral eye infections” (The Pirie/van Heyningen/Nordmann Guest Lecture). |
| September 2006 |
Eleventh International Wartburg Colloquim “Varicella and Zoster”, Deutschen Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) und der Paul-Ehrlich-Gesellschaft für Chemotherapie (PEG), Wartburg (Eisenach), Germany, 18-20 September 2006. |
| “Antiviral drugs against varicella-zoster virus” (VZV) (invited lecture). |
| August-September 2006 |
XIXIth International Symposium on Medicinal Chemistry, Istanbul, Turkey, |
| 29 August-2 September 2006. |
| -“New vistas for the treatment of DNA virus and retrovirus infections” (invited lecture). |
| -Chairman of the Session “New Vistas in Antiviral Research” (invited). |
| June 2006 |
First International Conference on Avian Influenza in Humans. Latest Advances on Prevention, Therapies and Protective Measures, Institut Pasteur, Paris, France, 29-30 June 2006. |
| -“Avian influenza in humans, existing treatments, their limits, and new perspectives” (invited lecture) |
| -Chairman, Session on H5N1 Detection, Treatments and Perspectives (invited). |
| May-June 2006 |
Bridging the Sciences: HIV, HBV, HCV and Emerging Viruses, Le Palais des Congrès de Paris, France, 31 May-2 June 2006 (Organizers Y. Benhamou and R.F. Schinazi). |
| “Bridging chemistry to HIV, HBV, HCV and poxvirus infections: the phosphonate bridge” (invited plenary lecture). |
| May 2006 |
International Cancer Vaccine Conference in association with Eighth (8th) ECEAR (European Conference on Experimental AIDS Research), Naples, Italy, 26-28 May 2006. |
| “New anti-HIV agents: recent advances” (invited lecture). |
| May 2006 |
Second VIRGIL International Symposium on Antiviral Drug Resistance (VIRGIL = European Network for the Vigilance against Antiviral Drug Resistance), Lyon, France, 23 May 2006. |
| “New antiviral drugs for HBV, HCV, HIV and influenza viruses. Inhibitors of influenza virus” (invited lecture). |
| May 2006 |
Nineteenth International Conference on Antiviral Research (ICAR), San Juan, Puerto Rico, 7-11 May 2006. |
| -International Society for Antiviral Research (ISAR) Conference Committee & Publication Committee and Program Committee Meetings |
| -Antiviral Research Editorial Board Meeting. |
| May 2006 |
Fifth International Conference on HHV-6 & 7, Barcelona, Spain, 30 April-3 May 2006. |
| -“In search of effective anti-HHV-6 agents” (invited lecture). |
| -Chairman of Session on Antivirals (invited). |
| March 2006 |
Sixth International Symposium on Ocular Pharmacology and Therapeutics (ISOPT), Berlin, Germany, 30 March-2 April 2006. |
| “Antiviral drugs” (invited lecture). |
| January 2006 |
Planning of the Nineteenth ICAR (International Conference on Antiviral Research, San Juan, Puerto Rico, 7-11 May 2006), ICAR Program Committee and Conference Committee meetings, 11 January 2006, Reston, Virginia, USA. |
| October 2005 |
Seventh European Congress of Chemotherapy and Infection, Federation of the European Societies for Chemotherapy and for Infection (FESCI), Florence, Italy, 19-22 October 2005. |
| “Antiviral drugs against varicella-zoster virus (VZV)” (invited lecture). |
| October 2005 |
Fourteenth Congress of the European Academy of Dermatology and Venereology (EADV), London, United Kingdom, 12-16 October 2005. |
| “Antiviral drugs” (invited lecture). |
| October 2005 |
Club de la Transplantation 2005, Infections Virales et Transplantations, Château hôtel Montroyal, La Chapelle en Serval, Chantilly, France, 6-7 October 2005. |
| “Développement de nouveaux traitements anti-viraux (Development of new antiviral treatments)” (invited lecture). |
| September 2005 |
Joint Meeting on “Fighting Infection: Challenges and Recent Advancements in Microbiology” of the Society for General Microbiology (UK), and the Societies for Medical Microbiology, Microbiology and Virology (Norway), Bergen, Norway, 27-30 September 2005. |
| “Antiviral drugs: old and new” (invited lecture). |
| May 2005 |
Twelfth Panhellenic Pharmaceutical Congress, Athens, Greece, 14-16 May 2005. |
| “Antivirals” (plenary lecture, invited). |
| May 2005 |
Trends in Drug Research. Fifteenth Noordwijkerhout-Camerino Symposium, Noordwijkerhout, The Netherlands, 8-13 May 2005. |
| Inaugural lecture “Successes and pitfalls in the development of antiviral drugs” (invited opening lecture). |
| April 2005 |
Eighteenth International Conference on Antiviral Research, Barcelona, Spain, 11-14 April 2005. “Antiviral drug development: where chemistry meets medicine” (Elion award lecture). |
| -Nomination Committee Meeting, Publication Committee Meeting, Program Committee Meeting, and Antiviral Research Editorial Board Meeting |
| March 2005 |
Annual Meeting of Finnish Virologists, Virologipäivät 2005, Haikko, Helsinki, Finland, 10-11 March 2005 |
| “Antiviral drugs” (keynote lecture, invited). |
| March 2005 |
Second Symposium, International Consortium on Anti-Virals (ICAV), Consortium International sur les Thérapies Antivirales (CITAV), Ministère des Solidarités, de la Santé et de la Famille, Paris, France, 8-10 March 2005. |
| “Antiviral therapies” (Inaugural Conference, invited). |
| January 2005 |
Scientific Symposium in honor of Dr. Maurice R. Hilleman, American Philosophical Society, Philadelphia, Pennsylvania, USA, 26 January 2005. |
| “Poly(I).poly(C): a fertile attraction. Antiviral activity of polynucleotides, nucleotides, and nucleosides” (invited lecture). |
| January 2005 |
Planning of the Eighteenth ICAR (International Conference on Antiviral Research, Barcelona, Spain, 10-14 April 2005), ICAR Program Committee and Conference Committee meetings, 5-6 January 2005, Reston, Virginia, USA. |
| December 2004 |
HIV DART 2004, Frontiers in Drug Development for Antiretroviral Therapies, Montego Bay, Jamaica, 12-16 December 2004. |
| -“The era of antiretroviral therapy: how it started and evolved” (invited, “Gertrude Elion Distinguished Award Lecture”). |
| -Chairman of session on “The Implications of Viral Drug Resistance for the Development of Antiretroviral Agents and the Management of Patients” (invited). |
| November-December 2004 |
International Symposium on Emergence and Control of Viral Respiratory |
| Diseases, Fondation Mérieux Conference Center “Les Pensières”, Veyrier-du-Lac, Annecy, France, , 30 November-3 December 2004. |
| “Antivirals for pandemic respiratory virus infections : the viruses, the compounds and the strategies” (invited lecture). |
| October 2004 |
The 50th Anniversary of the Rega Institute for Medical Research, University Hall, K.U.Leuven, Belgium, 8-9 October 2004. |
| Chairman of the three Symposia “Frontiers in Chemistry, Microbiology and Immunology”, “The Rega Institute: 50 Years of Medical Research”, and “HIV/AIDS, Antiretrovirals and the Developing World”, organized at the occasion of the 50th Anniversary of the Rega Institute. |
| September 2004 |
XVI International Round Table, International Society for Nucleosides, Nucleotides & Nucleic Acids, Minneapolis, Minnesota, USA, 12-16 September 2004. |
| “Antiviral potential of “new” acyclic nucleoside phosphonates, the 6-[2-(phos-phonomethoxy)alkoxy]-2,4-diaminopyrimidines (invited plenary lecture). |
| July 2004 |
Sixteenth International Conference on Phosphorus Chemistry (ICPC 2004), International Convention Centre, Birmingham, United Kingdom, 4-9 July 2004. |
| “Antiviral activity of acyclic nucleoside phosphonates” (invited lecture). |
| June 2004 |
First International Greek Biotechnology Forum, National Hellenic Research Foundation, Athens, Greece, 10-12 June 2004. |
| “New antiviral agents & strategies for the treatment of HIV infections (AIDS) (invited lecture). |
| June 2004 |
Thirteenth International Symposium on HIV and Emerging Infectious Diseases, International Convention Center, Toulon, France, 3-5 June 2004. |
| “The search for new antiretroviral drugs” (invited lecture). |
| May 2004 |
First National Congress of the Italian Society of Pharmaceutical Microbiology (1° Congresso Nazionale della Societa Italiana di Microbiologia Farmaceutica), Catania, Sicily, Italy, 28-30 May 2004. |
| “New antiviral (anti-HIV) compounds” (invited plenary lecture) |
| May 2004 |
Seventeenth International Conference on Antiviral Research (ICAR), Tucson, Arizona, USA, 2-6 May 2004. |
| -“SARS: a new challenge for antiviral therapy (glycopeptide antibiotic aglycons, mannose-specific lectins, etc.)” (oral presentation). |
| -ISAR (International Society of Antiviral Research) Committee Meetings: Nominations, Publications, Scientific Program, Scientific Awards and Conference. |
| -Antiviral Research Editorial Board Meeting. |
| April 2004 |
New Perspectives in Herpes Virus Infections (Organized by Universitá degli Studi di Roma “Tor Vergata” con il supporto di Menarini), Grand Hotel Parco dei Principi, Rome, Italy, 1-2 April 2004. |
| Lettura Magistrale: “Recenti sviluppi della terapia antierpetica” (Recent developments in the therapy of herpesvirus infections). |
| January 2004 |
ESCV (European Society for Clinical Virology) Winter Meeting, Copenhagen, Denmark, 15-17 January 2004. |
| “New antivirals” (invited keynote lecture). |
| January 2004 |
Planning of the Seventeenth ICAR (International Conference on Antiviral Research, Tucson, Arizona, USA, 2-6 May 2004), ICAR Program Committee and Conference Committee meetings, 8-9 January 2004, Dearborn, Michigan, USA. |
| January 2004 |
IX International Antiviral Symposium and Workshop, Beldibi, Antalya, Turkey, 9-11 November 2003. |
| “Therapeutic potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections” (invited lecture). |
|
| Keystone Symposium on “Bioterrorism and Emerging Infectious Diseases: Antimcrobials, Therapeutics and Immune-Modulators”, Keystone Resort, Keystone, Colorado, USA, 6-11 January 2004. |
| -“Therapeutic potential of nucleoside/nucleotide analogs against poxvirus infections” (invited plenary lecture). |
| -Chairman of Session on “New Information on Antiviral Mechanism of Action” (invited). |
| October 2003 |
“Twenty-five years on: smallpox revisited”, Retroscreen Virology and Institute of Cell and Molecular Sciences Barts and the London Queen Mary’s School of Medicine & Dentistry, The Great Hall, St. Bartholomew’s Hospital, London, Great Britain, 31 October 2003. |
| “Antiviral drugs against poxviruses” (invited lecture). |
| June-July 2003 |
Second European Society of Clinical Microbiology and Infectious Diseases (ESCMID) School, Utrecht, The Netherlands, 28 June-4 July 2003 |
| “New non-HIV antiviral agents” (invited lecture). |
| May 2003 |
9th International Cytomegalovirus Workshop and First International Betaherpesvirus Workshop, Maastricht, The Netherlands, 20-25 May 2003. |
| -“New inhibitors of human cytomegalovirus replication” (invited lecture). |
| -Chairman of session “Virus-host interaction” (invited). |
| May 2003 |
Sixteenth International Conference on Antiviral Research (ICAR), Savannah, Georgia, USA, 27 April-1 May 2003. |
| -“CMV423, a potent and selective inhibitor of human herpesvirus 6 exerts its antiviral action through inhibition of cellular protein tyrosine kinase activity” (presented on behalf of L. De Bolle). |
| -Chairperson of session on “Poxviruses” (invited). |
| -Participation in Antiviral Research Editorial Board Meeting and in Nomination Committee, Publications Committee, Conference Committee, Scientific Program Committee, and Scientific Awards Committee meeting of the International Society for Antiviral Research (ISAR). |
| January 2003 |
Second Chiba Institute of Technology Symposum (13th Annual Meeting of the Japanese Association of Antiviral Chemotherapy and 2nd Symposium of High Technology Research Center), Tsudanuma, Narashino, Chiba, Japan, 27-29 January 2003. |
| “Antiviral potential of acyclic nucleoside phosphonate analogues (cidofovir, adefovir, tenofovir)” (invited lecture and chairperson). |
| January 2003 |
Planning of the Sixteenth ICAR (International Conference on Antiviral Research, Savannah, Georgia, USA, 27 April-1 May 2003), ICAR Program Committee and Conference Committee meetings, 6-7 January 2003, Reston, Virginia, USA. |
| December 2002 |
HIV DART 2002, Frontiers in Drug Development for Antiretroviral Therapies (DART), Naples, Florida, USA, 15-19 December 2002. |
| “Drug discovery and development: the bicyclam AMD3100, a case in point” (invited lecture). |
| December 2002 |
Quinzièmes Entretiens du Centre Jacques Cartier, Nouveaux Traitements des Hépatitis Virales: de la Recherche à la Clinique, Lyon, France, 6-7 December 2002. |
| “Drug design progress” (invited keynote lecture). |
| October 2002 |
Therapies for Viral Hepatitis, Boston, Massachusetts, USA, 29-31 October 2002. |
| Chairman of Session on “Approaches to drug development” (invited). |
| October 2002 |
Tenth Congress of the Bulgarian Microbiologists (with International Participation), Plovdiv, Bulgaria, 9-12 October 2002. |
| “Recent advances in anti-HIV drug development” (invited plenary lecture). |
| September 2002 |
First International Meeting on Medicinal and Pharmaceutical Chemistry (IMMPC-1), Gazi University, Ankara, Turkey, 25-28 September 2002. |
| “Progress in anti-HIV drug design and developmen” (invited lecture). |
| September 2002 |
Fifteenth International Round Table on Nucleosides, Nucleotides and Nucleic Acids, Leuven, Belgium, 10-14 September 2002. |
| -Organizer and Chairman (with P. Herdewijn as Co-Organizer and Co-Chairman) of the International Round Table. |
| -Chairman of the Plenary Mystery Session. |
| -Board meeting of the International Society for Nucleosides, Nucleotides and Nucleic Acids (IS3NA). |
| September 2002 |
G7+ Global Health Security Action Group Workshop on “Best Practices in Vaccine Production for Smallpox and other Potential Pathogens”, Paul-Ehrlich-Institut, Langen, Germany, 5-6 September 2002. |
| “Potential of cidofovir in the treatment of poxvirus infections” (invited lecture). |
| August 2002 |
The 224th ACS (American Chemical Society) National Meeting, Division of Medicinal Chemistry Symposium on “Non-HIV Antivirals”, Boston, Massachusetts, USA, 18-22 August 2002. |
| “Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic nucleoside analogs” (invited lecture). |
| July 2002 |
XIVth World Congress of Pharmacology, San Francisco, California, USA, 7-12 July 2002. |
| -Symposium on “New Developments in Antiviral Agents” (Chairman). |
| -“Acyclic nucleoside phosphonates” (invited lecture). |
| June 2002 |
Third International Conference on Ocular Infections: Stepping into the New Millennium, Salzburg, Austria, 9-13 June 2002. |
| “Antiviral drug update: cidofovir” (invited keynote lecture). |
| June 2002 |
Seventh European Conference on Experimental AIDS Research (ECEAR 2002), Genoa, Italy, 8-11 June 2002. |
| -“New anti-HIV agents: recent advances” (invited plenary lecture). |
| -Chairman of Workshop 2 (Mutations and Drug Resistance) (invited). |
| May 2002 |
Microbicides 2002, Antwerp, Belgium, 12-15 May 2002. |
| “Potential candidate anti-HIV microbicides” (invited lecture). |
| May 2002 |
ConVir 2002, European Conference on Viral Diseases, Klinikum Grosshadern, Munich, Germany, 10-12 May 2002. |
| -“Development of resistance to antiviral therapy (invited plenary lecture)”. |
| -“Highly potent and selective inhibition of varicella-zoster virus (VZV) replication by bicyclic thymidine analogues (BCNAs)” (invited lecture). |
| -Chairman of Oral Presentation Session on Laboratory Parameters and Diagnosis of Viral Infections (invited). |
| April 2002 |
Eighteenth Annual Clinical Virology Symposium and Annual Meeting of the Pan American Society for Clinical Virology, Clearwater Beach, Florida, USA, 28 April-1 May 2002. |
| -Antiviral agents for the treatment of HIV infections (invited lecture). |
| March 2002 |
Fifteenth International Conference on Antiviral Research (ICAR), Prague, Czech Republic, 17-21 March 2002. |
| -International Society for Antiviral Research (ISAR) Committee meetings: Directors’ Board, Antiviral Research Editorial, Publications, Nominations, Conference, Scientific Program, Scientific Awards. |
| -Chairman of Session VI on Retroviruses II (invited). |
| March 2002 |
Symposium on “Clinical Evaluation of New HIV Therapies overcoming HIV Drug Resistance”, International Institute of Research (IIR), Thistle Westminster, London, United Kingdom, 7-8 March 2002. |
| “Developing new anti-HIV agents and targets” (invited lecture). |
| February 2002 |
Second Konsensuskonferenz zur Therapie und Diagnostik des Herpes Zoster, Paul-Ehrlich-Gesellschaft für Chemotherapie, Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten, Erfurt, Germany, 7-8 February 2002. |
| “New virustatics for the treatment of herpes zoster” (invited lecture). |
| October 2001 |
Second International Conference on Retroviral Integrase, A Novel Target for the Treatment of AIDS, Paris, France, 28-30 October 2001. |
| “Introduction to anti-HIV drugs and targets” (invited plenary lecture). |
| October 2001 |
Second Congress of the European Society for Emerging Infections (ESEI), Budapest, Hungary, 21-23 October 2001. |
| “New developments in the search of anti-HIV agents”. |
| September 2001 |
Eighth International Symposium on Molecular Aspects of Chemotherapy, Gdansk, Poland, 5-9 September 2001. |
| -“New developments in anti-HIV chemotherapy” (invited lecture). |
| -Chairman of Session on Antivirals (invited). |
| July 2001 |
XXXVIIèmes Rencontres Internationales de Chimie Thérapeutique (37th International Meeting on Medicinal Chemistry), Tours, France, 4-6 July 2001. |
| “New developments in anti-HIV chemotherapy” (invited lecture). |
| July 2001 |
Twenty-Second International Congress of Chemotherapy, Amsterdam, The Netherlands, 30 June-3 July 2001. |
| “An Odyssey in the Viral Chemotherapy Field” (Hamao Umezawa Memorial Award Lecture). |
| June 2001 |
Eleventh Symposium on HIV Infection; AIDS 2001: Third Decade of an Odyssey, Toulon, France, 14-16 June 2001. |
| “Bicyclam AMD3100 and derivatives as selective CXCR4 receptor anagonists and potent inhibitors of HIV infection” (invited lecture). |
| May 2001 |
Fourth International Conference on Human Herpesviruses 6, 7 and 8, Institut Pasteur, Paris, France, 10-12 May 2001. |
| “Antiherpetic drugs active against HHV-6, HHV-7 and HHV-8” (invited lecture). |
| April 2001 |
COST Chemistry Action D13 on New Molecules Towards Human Health Care, National Hellenic Research Foundation, Athens, Greece, 26-28 April 2001. |
| “Chemotherapy of human immunodeficiency virus (HIV) infections” (invited lecture). |
| April 2001 |
Fourteenth International Conference on Antiviral Research (ICAR), Seattle, Washington, USA, 8-12 April 2001. |
| -Chairman of Session IV (Minisymposium) (invited). |
| -Discussant in Publications Committee, Conference Committee, Nominations Committee, Program Committee and Awards Committee meetings of the International Society for Antiviral Research (ISAR). |
| April 2001 |
221st ACS (American Chemical Society) National Meeting, San Diego, California, USA, 1-5 April 2001. |
| “CXCR4 receptor antagonist, AMD3100, is a potent inhibitor of HIV infection” (invited lecture at the “Symposium on Antagonists of HIV Entry – Potential New Therapies for Treatment of HIV Infection”, Division of Medicinal Chemistry) (invited lecture). |
| March-April 2001 |
Experimental Biology 2001, Annual Meeting of ASPET (American Society of Pharmacology and Experimental Therapeutics), Orlando, Florida, USA, 30 March-4 April 2001. |
| “Molecular targets for antiviral agents” (invited, Otto Krayer Award Lecture). |
| March 2001 |
The 2001 Palm Springs Symposium on HIV/AIDS. The Development of Antiviral Therapies, Palm Springs, California, USA, 8-11 March 2001. |
| “Anti-HIV agents targeted at the HIV co-receptors for viral entry” (invited lecture). |
| January 2001 |
Winter Meeting of the European Society for Clinical Virology, Ghent, Belgium, 11-13 January 2001. |
| “New developments in antiviral chemotherapy” (invited keynote lecture). |
| December 2000 |
HIV DART 2000, Frontiers in Drug Development for Antiretroviral Therapies, Isla Verde, Puerto Rico, 17-21 December 2000. |
| Chairman, session “Drug Design and Discovery: Viral Targets”. |
| December 2000 |
Collaborative Research Seminar on HIV Entry and Fusion Inhibition, St. Lucia, Windward Islands, 8-10 December 2000. |
| “Bicyclams as CXCR4 antagonists” (invited lecture). |
| November 2000 |
Eighth International Antiviral Symposium and Workshop. Eleventh Annual Meeting of the Japanese Association of Antiviral Chemotherapy, Shimin Bunka Hall, Kagoshima, Japan, 19-21 November 2000. |
| -“Inhibition of HIV infection by chemokine receptor CXCR4 and CCR5 antagonists” (invited lecture). |
| -Chairman of Oral Session (invited). |
| September 2000 |
XVIth International Symposium on Medicinal Chemistry, Bologna, Italy, 18-22 September 2000. |
| -“New developments in antiviral chemotherapy” (plenary lecture, invited). |
| September 2000 |
XIVth International Round Table on Nucleosides, Nucleotides and their Biological Applications, San Francisco, California, USA, 10-14 September 2000. |
| -“Antiviral activity spectrum of carbocyclic and acyclic guanosine analogues” (invited lecture). |
| -Invitation to the XVth International Round Table (invited lecture). |
| September 2000 |
The Jack Fox Satellite Symposium, XIVth International Round Table on Nucleosides, Nucleotides and their Biological Applications, San Francisco, California, USA, 10-14 September 2000, Satelllite Symposium held on 10 September 2000. |
| “Antiviral activity of nucleoside analogues: the BVDU connection” (invited lecture). |
| September 2000 |
First Symposium of High Technology Research Center, Chiba Institute of Technology, Tsudanuma, Narashino, Chiba, Japan, 6-7 September 2000. |
| “New developments in anti-HIV chemotherapy” (invited lecturer and chairman). |
| June 2000 |
Fourth International Workshop on HIV Drug Resistance and Treatment Strategies, Sitges, Spain, 12-16 June 2000. |
| Chairman of Session on “New antiretrovirals” (invited). |
| May 2000 |
Second International Conference on Signal Transduction (ICST), Dubrovnik (Cavtat), Croatia, 26-31 May 2000. |
| “Chemokine receptor (CXCR4, CCR5) antagonists as anti-HIV agents” (invited selected talk). |
| May 2000 |
The 16th Philippine Chemistry Congress, Chemistry for the New Millenium, Manila Hotel, Rizal Park, Manila, The Philippines, 22-24 May 2000. |
| “New developments in the chemotherapy of HIV infections” (invited plenary lecture). |
| May 2000 |
Third European Congress of Chemotherapy, Madrid, Spain, 7-10 May 2000. |
| -“New developments in anti-HIV chemotherapy” (invited expert lecture). |
| -“Drug resistance in herpesviruses (HSV, CMV)” (invited lecture). |
| -“Antiviral drugs in the treatment of virus-associated tumours” (invited lecture). |
| -Chairman of Session “What is important in resistance to antivirals ?” (invited). |
| -Chairman of Session “Pharmacology of antiviral drugs” (invited). |
| April 2000 |
Thirteenth International Conference on Antiviral Research, Baltimore, Maryland, USA, 16-21 April 2000. |
| -Participation in Directory Board Meeting, Publications Committee Meeting, Awards Committee Meeting, Nominations Committee Meeting and Program Committee Meeting of the International Society for Antiviral Research. |
| -“Antiviral Research” Editors’ Meeting. |
| -Chairman of Session on Retrovirus Infections II (invited). |
| March-April 2000 |
Second International Conference on HIV and Iron, Brugge, Belgium, 31 March-1 April 2000. |
| Chairman of Session on “HIV, Iron and Oxidative Stress” (invited). |
| March 2000 |
Seventh IBN SINA International Conference on Pure and Applied Heterocyclic Chemistry, Alexandria, Egypt, 25-28 March 2000. |
| -“Novel approaches, compounds and targets for anti-HIV chemotherapy” (invited lecture). |
| -Chairman of Section of “Nucleosides” (invited). |
| February- March 2000 |
Fachgruppentagung der Deutschen Pharmazeutischen Gesellschaft, Fachgruppe |
| Pharmazeutische Chemie, Hamburg, Germany, 28 February-1 March 2000. |
| “New insights in the chemotherapy of HIV infections” (invited lecture), Lecture presented by J. Balzarini. |
| January-February 2000 |
Seventh Conference on Retroviruses and Opportunistic Infections, San Francisco, |
| California, USA, 30 January-2 February 2000. |
| Symposium on New Drug Targets: Entry Inhibitors. |
| “Bicyclams as CXCR4 antagonists” (invited lecture). |
| December 1999 |
Recent Developments in the Discovery of Biologically Active Natural Products, joint 4th Annual Convention of the Natural Products Society of the Philippines and 21st Annual Convention of the Philippine Environmental Mutagen Society, Ateneo de Manila University, Loyola Heights, Quezon City, Manila, Philippines, 6-8 December 1999. |
| “New developments, with particular emphasis on natural products, for the chemotherapy of HIV infections” (invited plenary lecture). |
| October 1999 |
104th Annual American Osteopathic Medicine Association (AOA) Convention, and 43rd Annual AOA Research Conference, San Francisco, California, USA, 24-28 October 1999. |
| “Viral infections of the 21st Century” (invited keynote lecture). |
| September 1999 |
Fifth International MonteCarlo Congress on Microbial Strategies and Antimicrobial Defences (coping with Antimicrobial Resistance in the Treatment of Infectious Diseases), MonteCarlo, Monaco, 12-15 September 1999. |
| -Chairman of Symposium on New Concepts about Resistance to Antiviral Drugs (invited). |
| -“Resistance of herpes simplex virus, hepatitis B virus and influenza virus to antiviral drugs” (invited lecture). |
| July 1999 |
Twenty-First International Congress of Chemotherapy (ICC), Birmingham, United Kingdom, 4-7 July 1999. |
| -“New targets for the chemotherapy of HIV infections” (invited lecture). |
| -Chairman of the Symposium on BSE and Prion Disease (invited). |
| June 1999 |
VIII Congreso Argentina de Farmacia y Bioquimica Industrial, Asociación Argentina de Farmacia y Bioquimica Industrial (SAFYBI), Buenos Aires, Argentina, 14-19 June 1999. |
| “Nuevas perspectivas para el tratamiento de infecciones HIV: Está proxima la cura del SIDA ?” (Conferencia plenaria) – “New perspectives for the treatment of HIV infections: is a cure for AIDS forthcoming ?” (plenary lecture). |
| June 1999 |
KNCV (Koninklijke Nederlandse Chemische Vereniging) Secties Organische Chemie en Farmacochemie, Organische Chemie van Geneesmiddelen: De Natuur als Inspiratiebron, WICC-IAC, Wageningen, The Netherlands, 11 June 1999. |
| “New perspectives for the treatment of HIV infections” (invited lecture). |
| May 1999 |
Symposium on Human Herpesvirus Infections: Molecular, Immunological and Clinical Aspects, Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten, Freie Universität Berlin, Germany, 29 May 1999. |
| “Antiviral therapy of herpesvirus infections” (invited lecture). |
| May 1999 |
International Symposium on HIV, Leukemia, and Opportunistic Cancers, Twentieth Symposium of the International Association for Comparative Research on Leukemia and Related Diseases, Harvard AIDS Institute, Marrakech, Morocco, 23-28 May 1999. |
| “Novel therapeutic strategies for the treatment of HIV infections” (invited plenary lecture). |
| May 1999 |
V Congreso Nacional de Quimioterapia, Sociedad Espanola de Quimioterapia, Cádiz, Spain, 20-22 May 1999. |
| “New antiviral drugs” (“Nuevos Antiviricos”) (invited lecture). |
| April 1999 |
Clinical Virology Group Symposium on Antivirals, 143rd Meeting of the Society for General Microbiology (SGM), The University of Edinburgh, Scotland, United Kingdom, 12-16 April 1999. |
| “New developments in anti-herpres agents” (invited lecture). |
| March 1999 |
Twelfth International Conference on Antiviral Research, Jerusalem, Israel, 21-25 March 1999. |
| -Chairman of Session on Retrovirus Infections II (invited). |
| -Board of Directors Meeting, Publications Committee Meeting, Nominations Committee Meeting, Program Committee Meeting (International Society of Antiviral Research). |
| -Editorial Board Meeting (Antiviral Research). |
| March 1999 |
European Conference on “Chemokines and their Receptors: from Basic Research to Therapeutic Intervention”, Institut Pasteur, Paris, France, 11-13 March 1999. |
| “Inhibition of HIV infection by bicyclams” (invited lecture). |
| February 1999 |
Tenth Annual Meeting of the Japanese Association of Antiviral Chemotherapy, Showa University School of Pharmaceutical Sciences, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, Japan, 19-20 February 1999. |
| “New perspectives for the chemotherapy of HIV infections” (plenary invited lecture). |
| December 1998 |
Scientific Program Committee Meeting of the 12th International Conference on Antiviral Research (Jerusalem, Israel, 21-26 March 1999), Washington DC, USA, 17-18 December. |
| December 1998 |
International Conference on the Discovery and Clinical Development of Antiretroviral Therapy (ICDCD), St. Thomas, West Indies, US Virgin Islands, 13-17 December 1998. |
| “Bicyclams: a class of highly potent anti-HIV agents that block viral entry into the cell at CXCR4” (invited lecture). |
| December 1998 |
Dix-huitième Réunion Interdisciplinaire de Chimiothérapie Anti-Infectieuse Symposium “Nouvelle classe, nouvelles stratégies anti-VIH. Viramune®: Premier inhibiteur non-nucléosidique”, Paris, France, 3-4 December 1998. |
| “Les inhibiteurs non-nucléosiques de la reverse transcriptase (NNRTIs)” (invited lecture). |
| September 1998 |
XIV Convegno Nazionale, Divisione di Chimica Farmaceutica, Società Chimica Italiana, Salsomaggiore Terme, Parma, Italy, 21-25 September 1998. |
| “The chemotherapy of HIV infections: current approaches and perspectives” (invited lecture). |
| September 1998 |
Nineth Wartburg Kolloquium der Paul-Ehrlich Gesellschaft für Chemotherapie (PEG) und der Deutschen Vereinigung zur Bekämpfung der Viruskrankheiten (DVV), Wartburg bei Eisenach, Germany, 14-16 September 1998. |
| “Development of antiherpetics after Aciclovir” (invited lecture). |
| September 1998 |
Thirteenth International Round Table on Nucleosides, Nucleotides and their Biological Applications, “Le Corum”, Montpellier, France. |
| “Antitumor potential of acyclic nucleoside phosphonates” (invitecd plenary lecture). |
| August-September 1998 |
European Society for Clinical Virology (ESCV), Progress in Clinical Virology, |
| Hamburg, Germany, 30 August-2 September 1998. |
| “New chemotherapeutic approaches in the treatment of HIV infections” (invited keynote lecture). |
| August 1998 |
1998 Annual Meeting of the Institute of Human Virology, Baltimore, Maryland, USA, 23-29 August 1998. |
| “Bicyclams: highly potent T-tropic HIV inhibitors that are targeted at the chemokine receptor CXCR4” (invited lecture). |
| August 1998 |
Second International Conference on Ocular Infections, Munich, Germany, 22-26 August 1998. |
| -“The broad-spectrum antiviral potential of cidofovir” (invited lecture). |
| -“Antiviral drugs for the treatment of ocular virus infections” (invited lecture). |
| -Chairman of Invited Course on New Antiviral Drugs (Cidofovir and New Antivirals) (invited). |
| -“Recent developments in the field of antiviral drug development” (invited keynote lecture). |
| June 1998 |
Second International Workshop on HIV Drug Resistance and Treatment Strategies, Baveno, Stresa, Lago Maggiore, Italy, 24-27 June 1998. |
| Invited as Chairman of Session on New Antiretrovirals. |
| June 1998 |
Nobel Conference on “Pathogenesis and Treatment of HIV Infection”, Karolinska Institute, Nobel Forum, Stockholm, Sweden, 4-6 June 1998. |
| “New drugs and new perspectives for antiretroviral therapy” (invited lecture). |
| May 1998 |
Second European Congress of Chemotherapy and Seventh Biennial Conference on Antiinfective Agents and Chemotherapy, Hamburg, Germany, 10-13 May 1998. |
| -“New HIV drugs” (invited lecture). |
| -Chairman of Session on “Aspects of antiretroviral therapy” (invited). |
| May 1998 |
Second European Congress of Chemotherapy and Seventh Biennial Conference on Antiinfective Agents and Chemotherapy, Hamburg, Germany, 10-13 May 1998. |
| -“New drugs under development against herpesviruses” (invited lecture). |
| -Chairman of Session on “Progress in the treatment of herpesviruses” (invited). |
| April 1998 |
Eighth European Course on Human Papillomavirus-Associated Pathology (ECHPV), Universität München rechts der Isar, Munich, Germany, 23-24 April 1998. |
| “HPMPC (cidofovir), a broad spectrum antiviral agent with efficacy in HPV-associated diseases” (invited lecture). |
| April 1998 |
Eleventh International Conference on Antiviral Research, San Diego, California, USA, 5-10 April 1998. |
| Board of Directors Meeting, Program Committee Meeting, Nominations Committee Meeting, Conference Committee Meeting, Publications Committee Meeting of ISAR (International Society for Antiviral Research), and Editorial Board Meeting of the Journal Antiviral Research. |
| April 1998 |
Eleventh International Conference on Antiviral Research, San Diego, California, USA, 5-10 April 1998. |
| -“The role of NNRTIs in the therapy of HIV-1 infections” (invited plenary lecture). |
| -Chairman of the Symposium on the Use of Viral Vectors in Gene Therapy (invited). |
| February-March 1998 |
Third European Conference on Experimental AIDS Research (ECEAR), Munich, |
| Germany, 28 February-3 March 1998. |
| Organizer, Chairman, and Introductory Speaker of the Opening Session on “Advances in antiretroviral drug design” (invited). |
| January 1998 |
Elmau Workshop on “Viral Receptors and Co-receptors and Their Impact on Vaccination and Therapy”, Elmau, Garmisch-Partenkirchen, Germany, 30 January-1 February 1998. |
| “Bicyclam AMD3100, a highly potent anti-HIV agent that is targeted at the CXCR4 co-receptor for HIV” (invited lecture). |
| January 1998 |
Program Committee Meeting, 11th International Conference on Antiviral Research, San Diego, California, USA (5-10 April 1998), Washington DC, USA, 27 January 1998. |
| December 1997 |
Second International Conference on Therapies for Viral Hepatitis, Kona, Big Island, Hawaii, USA, 15-19 December 1997 (hosts: Prof. R. Schinazi and Prof. J.-P. Sommadossi). |
| December 1997 |
XIIièmes Journées Scientifiques, Groupe Thématique de Recherche sur les Vecteurs, under the patronage of La Société Belge des Sciences Pharmaceutiques, Palais des Congrès, Brussels, Belgium., 11-12 December 1997. |
| “Recent developments in AIDS treatment” (plenary invited lecture). |
| November 1997 |
XI Congresso Nazionale AIDS e Sindromi Correlate, Simposio Satellite L’Evoluzione della storia naturale e della gestione della infezioni opportunistische maggiori, Pisa, Italy, 12-13 November 1997. |
| “Cidofovir: a new agent with potent antiviral activity” (invited lecture). |
| October 1997 |
The IVth Congress of the Mediterranean Society of Infectious and Parasitic Diseases and the 1st Congress of the Arab Society of Chemotherapy, Microbiology and Infectious Diseases, Cairo, Egypt, 17-21 October 1997. |
| -“Antiretroviral agents: past, present and future” (invited lecture). |
| -Chairman of Symposium on HIV infection (invited). |
| October 1997 |
“Perspektiven der Therapie von Virusinfektionen”, Gemeinsame Jahrestagung Deutsche Vereinigung zür Bekämpfung der Viruskrankheiten (DVV) und Gesellschaft für Virologie (GfV), Berlin, Germany, 10-11 October 1997. |
| “Prospects of antiviral therapy” (special guest lecture). |
| September 1997 |
NWO (Nederlandse Organisatie voor Wetenschappelijk Onderzoek) and Dutch AIDS Fund Symposium on “New developments in HIV-AIDS Research”, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, 12 September 1997. |
| “New antiviral drugs” (invited lecture). |
| September 1997 |
Second Congress of the European Association for Clinical Pharmacology and Therapeutics, Berlin, Germany, 17-20 September 1997. |
| “Successes and failures in AIDS therapy” (invited plenary lecture). |
| September 1997 |
Congrès de la Société Française de Chimie (SFC 1997), Bordeaux-Talence, France, 7-12 September 1997. |
| “Molecular targets for the chemotherapy of HIV infections” (invited lecture). |
| August 1997 |
First International Consensus Round Table Meeting on CMV-Related Immunopathology, Frankfurt am Main, Germany, 28-30 August 1997. |
| “Outlook for antiviral drugs” (invited lecture). |
| July-August 1997 |
Asian International Medicinal Chemistry Symposium (AIMECS 97), Asian Federation for Medicinal Chemistry (AFMC), Seoul, Korea, 27 July-1 August 1997. |
| “Recent developments in the chemotherapy of HIV infections (invited plenary lecture). |
| June 1997 |
International Workshop on HIV Drug Resistance, Treatment Strategies and Eradication, St. Petersburg, Florida, USA, 25-28 June 1997. |
| Chairman, Session on New Antiretrovirals (invited). |
| June 1997 |
Nineteenth National Congress of the Italian Society of Chemotherapy, 19° Congresso Nazionale della Società Italiana di Chemioterapia, Centro Congressi, Giardini Naxos, Italy (Sicily), 11-14 June 1997. |
| Lettura Magistrale: “New perspectives for the chemotherapy of HIV infections” (invited lecture). |
| June 1997 |
IBC (International Business Communications) Conference on Antimicrobial Drug Resistance, The Royal Society, London, Great Britain, 9-10 June 1997. |
| -“Current trends in anti-HIV therapy; paradigm for the future of antiviral therapy” (invited). |
| -Chairman of Session on HIV (Human Immunodeficiency Virus) (invited). |
| May 1997 |
Second European Conference on Experimental AIDS Research (ECEAR), Stockholm, Sweden, 31 May - 3 June 1997. |
| Chairman of Session “Therapy: antivirals and combination therapies” (invited). |
| May 1997 |
Eleventh Noordwijkerhout-Camerino Symposium on Trends in Drug Research, Royal Netherlands Chemical Society, European Federation for Medicinal Chemistry, Noordwijkerhout, The Netherlands, 11-15 May 1997. |
| -“Novel approaches towards HIV chemotherapy” (invited lecture). |
| -Chairman of Symposium on Anti-HIV Approaches (invited). |
| April 1997 |
International Seminar Series on Basic and Applied Sciences “The Biological Bases of AIDS: Clinical Studies”, Segovia, Spain, 24-26 April 1997. |
| “Preclinical development of antiviral drugs” (invited lecture). |
| April 1997 |
Worldwide Vistide Launch Meeting, Madrid, Spain, 15-16 April 1997. |
| -“Cidofovir (Vistide, HPMPC): how it was discovered and developed” (invited keynote lecture). |
| -Discussion on the clinical utility of cidofovir. |
| April 1997 |
Tenth International Conference on Antiviral Research, Atlanta, Georgia, USA, 6-11 April 1997 |
| -Chairman of Session on Retrovirus Infections II (invited). |
| -Panel discussant in Satellite Symposium on “HIV Resistance Impact on Patient Management” (invited). |
| -Participant in ISAR (International Society for Antiviral Research) meetings: |
| - Board of Directors meeting |
| - Publications Committee meeting |
| - Conference Committee meeting |
| - Nominations Committee meeting |
| - Program Committee meeting. |
| March 1997 |
Paul-Ehrlich-Gesellschaft Konsensus Konferenz zur Antiviralen Chemotherapie des Herpes Zoster, Erfurt, Germany, 17-19 March 1997. |
| “Brivudin (BVDU): Wirkspektrum und Mechanismus der antiviralen Aktivität” (invited lecture). |
| February 1997 |
Seventh International Antiviral Symposium, Sydney, Australia, 17-19 February 1997. |
| -“Anti-HIV infection treatment strategies based on the use of highly potent non-nucleoside reverse transcriptase inhibitors (NNRTIs)” (invited lecture). |
| -Chairman of Section “Antivirals for HIV and hepatitis” (invited). |
| January 1997 |
European Union Cost Action D8 Workshop on “Chemistry of Metals in Medicine - The Industrial Perspective”, Louvain-La Neuve, Belgium, 22-24 January 1997. |
| “Antiviral metal complexes” (invited lecture). |
| December 1996 |
Program Committee Meeting of the Tenth International Conference on Antiviral Research (Atlanta, Georgia, USA, 6-11 April 1997) and Board of Directors Meeting of the International Society for Antiviral Research, Atlanta, GA, USA, 10-11 December 1996. |
| December 1996 |
The 17th National Chemical Conference, “Chemistry on the Threshold of the 21st Century”, Patras, Greece, 1-5 December 1996. |
| “Perspectives for the treatment of HIV infection” (invited lecture). |
| November 1996 |
Medical Scientific Day 1996 on “New Developments in Infectious Diseases”, Dutch Federation of Medical Scientific Societies, Dutch Society of Medical Microbiology and Infectious Diseases Society of the Netherlands and Flanders, Amersfoort, The Netherlands, 21 November 1996. |
| GlaxoWellcome Award presentation on “Highlights in the development of antiviral drugs”. |
| October 1996 |
Eurogin Conference on Herpes Viruses and Genital Pathology, IUVDT European Congress on STDs, Palais des Congrès, Paris, France, 23-25 October 1996. |
| -“New antiviral drugs for herpes virus infections” (invited lecture). |
| -Chairman, and concluding remarks, of Session on “Management strategies and antiviral chemotherapy” (invited). |
| October 1996 |
Jahrestagung der Deutschen STD Gesellschaft. Joint Meeting mit der Paul-Ehrlich-Gesellschaft und dem European Course on HPV-Associated Pathology, Warnemünde/Rostock, Germany, 11-12 October 1996. |
| “Present developments of antiviral drugs against HSV, HIV, HBV and HPV infections” (invited guest lecture). |
| September 1996 |
VII Österreichischer AIDS-Kongress, Österreichische AIDS-Gesellschaft (Präsident: Prof. Dr. M.P. Dierich), Haus der Industrie, Schwarzenbergplatz, Vienna, Austria, 20-21 September 1996. |
| “New perspectives for the treatment of HIV infection” (invited lecture). |
| September 1996 |
Thirty-Sixth Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana, USA, 15-18 September 1996. |
| “In search of a selective chemotherapy of virus infections” (Hoechst Marion Roussel Award Lecture). |
| September 1996 |
First Annual Meeting of the Institute of Human Virology (Director: Dr. R.C. Gallo), Baltimore, Maryland, USA, 7-13 September 1996. |
| “Highly favorable antiviral activity profiles of the thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of HIV-1 replication” (invited lecture). |
| July 1996 |
Eleventh International Conference on AIDS, Vancouver, Canada, 7-12 July 1996. |
| -Chairman of Basic Science Session on “New Developments in Antiretroviral Research” (invited). |
| -“Novel targets of antiretroviral therapy” (invited expert lecture). |
| July 1996 |
Fifth International Workshop on HIV Drug Resistance, Whistler, British Columbia, Canada, 3-6 July 1996. |
| Chairman of Session on Functional and Structural Aspects of RT Inhibitor Resistance (invited). |
| June 1996 |
VII Congreso Argentino de Farmacia y Bioquimica Industrial, Buenos Aires, Argentina, 3-8 June 1996. |
| “Antiviral drugs for the treatment of human immunodeficiency virus infections” (invited plenary lecture). |
| May 1996 |
Post-Congress Satellite Symposium of the 9th International Conference on Antiviral Research, Fukushima City, Japan, 24 May 1996. |
| Chairman of session on “How to develop new antiviral drugs” (invited). |
| May 1996 |
Ninth International Conference on Antiviral Research, Urabandai (Fukushima), Japan, 19-24 May 1996. |
| -Chairman of Session on Retrovirus Infections (invited). |
| -International Society for Antiviral Research meetings of Board of Directors, Publications Committee, Conference Committee and Program Committee. |
| -Antiviral Chemistry and Chemotherapy Editorial Board Meeting. |
| May 1996 |
First European Congress of Chemotherapy, Glasgow, Scotland, 14-17 May 1996. |
| “Antiviral drugs: current status and prospects” (Expert Lecture) (invited). |
| April 1996 |
Societa Chimica Italiana, Consiglio Nazionale Delle Ricerche, Interazione di Metalli E Composti con Biomolecole 7° Convegno Nazionale, S. Agnello (Sorento), Italy, 12-14 April 1996. |
| Conferenza plenaria on “Development of inhibitors of human immunodeficiency virus (HIV) replication” (invited lecture). |
| March 1996 |
First European Conference on Experimental AIDS Research (ECEAR), Cannes, France, 10-13 March 1996. |
| Chairman of Session on Anti-HIV Therapies: Fundamental and Clinical Aspects + Summary (invited). |
| January 1996 |
Program Committee Meeting (Ninth International Conference on Antiviral Research, Urabandai, Fukushima, Japan, 19-24 May 1996), Washington DC, USA, 26-27 January 1996. |
| January 1996 |
INSERM (Institut National de la Santé et de la Recherche Médicale), Atelier de Formation no 78, La Transcriptase Inverse de VIH 1, Cible de Composés Antiviraux (HIV 1 Reverse Transcriptase, A Target for Antiviral Drugs), Le Vésinet, Paris, France, 22-24 January 1996 |
| -"Nucleoside and nucleotide inhibitors of the HIV reverse transcriptase" (invited lecture). |
| -"Non-nucleoside inhibitors of the HIV-1 reverse transcriptase" (invited lecture). |
| November 1995 |
Kagoshima International Symposium on "Oncovirus and Upper Aero-Digestive Tract Diseases", Kagoshima University, Faculty of Medicine, Kagoshima, Japan, 2-3 November 1995. |
| "Clinical potential of HPMPC (Cidofovir, Vistide) for the treatment of herpes- and papillomavirus infections" (invited special lecture). |
| October 1995 |
Management Forum on "The Development of Antiviral Drugs", London Hilton on Park Lane, London, United Kingdom, 9-10 October 1995. |
| "The current prospects for antiviral chemotherapy" (invited lecture). |
| September-October 1995 |
International Symposium on Experimental and Clinical Ocular Pharmacology and |
| Pharmaceutics, Geneva, Switzerland, 28 September-1 October 1995. |
| -"Therapy of ocular virus infections" (invited lecture). |
| -Chairman of Session on Antivirals (invited). |
| September 1995 |
Eighth Wartburgkolloquium, Antivirale Chemotherapie von Herpesvirusinfektionen, Friedrich-Schiller-Universität Jena, Paul-Ehrlich-Gesellschaft für Chemotherapie, Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten, Wartburg bei Eisenach, Germany, 18-20 September 1995. |
| "Antiviral chemotherapy of herpesvirus infections" (invited key note lecture). |
| September 1995 |
Symposium on Structure and Biological Functions of Nucleic Acid Components and Their Analogues, and Related Topics (in honor of Prof. Dr. David Shugar on the occasion of his 80th birthday), Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland, 2-5 September 1995. |
| "Nucleoside analogues as antiviral agents" (invited lecture). |
| August-September 1995 |
Annual (1995) Meeting of the Laboratory of Tumor Cell Biology (Dr. R.C. Gallo), |
| National Cancer Institute, 27 August-2 September 1995, Bethesda, Maryland, USA. |
| "In search of the ideal drug candidate among the thiocarboxanilide class of non-nucleoside reverse transcriptase inhibitors (NNRTIs)" (invited lecture). |
| August-September 1995 |
Second Congresso Congiunto Italiano-Spagnolo di Chimica Farmaceutica, Con- |
| gress Palaca, Ferrara, Italy, 30 August-3 September 1995. |
| "Knocking out human immunodeficiency virus (HIV) through non-nucleoside reverse transcriptase inhibitors (NNRTIs): a paradigm for the cure of AIDS ?" (invited plenary lecture). |
| July 1995 |
The 19th International Congress of Chemotherapy, Montréal, Québec, Canada, 16-21 July 1995. |
| -"Antiviral chemotherapy strategies in the aftermath of HIV and HSV resistance" (invited lecture). |
| -Chairman of Session on Viral Resistance (invited). |
| July 1995 |
Fourth International Workshop on HIV Drug Resistance, Margherita di Pula, Cagliari, Sardinia, Italy, 6-9 July 1995. |
| Chairman of session on "In vitro Resistance to Protease Inhibitors" (invited). |
| June 1995 |
International Conference on Ocular Infections, Jerusalem, Israel, 18-22 June 1995. |
| -"Antiviral drugs: new developments" (invited lecture). |
| -"Perspectives for the treatment of herpetic eye infections". |
| -Chairman of the session "Research IV: Viral and Bacterial Infections" (invited). |
| May 1995 |
The Fifth International Cytomegalovirus Conference "A multidisciplinary approach towards controlling cytomegalovirus disease", Stockholm, Sweden, 21-24 May 1995. |
| Chairman of Session on "Molecular Targets for Therapy" (invited). |
| May 1995 |
Fourth Conference in Advanced Medicinal Chemistry, Modern Approaches in Drug Design, Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, Thessaloniki, Greece, 19-20 May 1995. |
| "Inhibition of human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitors (NNRTIs)" (invited lecture). |
| May 1995 |
XIII Helsinki University Course in Drug Research, XXXVIII Nordic Meeting of Pharmacology, Helsinki, Finland, 18-20 May 1995. Symposium on Novel Drugs: Development and Analysis in Biological Samples |
| "Novel approaches towards the chemotherapy of human immunodeficiency virus (HIV) infection (invited lecture)". |
| April 1995 |
Eighth International Conference on Antiviral Research, Santa Fe, New Mexico, USA, 23-28 April 1995. |
| -Meetings of the Board of Directors (International Society for Antiviral Research), Scientific Program Committee, International Conference Committee, and Publications Committee. |
| -Editorial Board Meetings of the Journals Antiviral Research and Antiviral Chemistry and Chemotherapy. |
| -Chairman (invited) of the Mini-Symposium on "Molecular Targets/Gene Expression". |
| March 1995 |
Consultation Meeting on the Progress in Development and Use of Antiviral Drugs and Interferon, WHO (World Health Organization) Headquarters, Geneva, Switzerland, 13-15 March 1995. |
| -"Trends in the development of new antiviral agents for the chemotherapy of herpes- and retrovirus infections" (invited lecture). |
| -Chairman of the Meeting (invited). |
| February 1995 |
Seventh European Congress on Biotechnology, Acropolis, Nice, France, 19-23 February 1995. |
| -"Chemotherapy of human immunodeficiency virus (HIV) infections" (invited lecture). |
| -Chairman of session "AIDS: New Chemotherapeutic Agents" (invited). |
| February 1995 |
Gordon Research Conference on Chemotherapy of AIDS, Ventura, California, USA, 19-24 February 1995. |
| Discussion Leader of session on "HIV drug resistance" (invited). |
| January 1995 |
Program Committee Meeting (Planning of Eighth International Conference on Antiviral Research, Santa Fe, New Mexico, USA, 23-28 April 1995), Washington DC, 13 January 1995. |
| October 1994 |
Management Forum Meeting on "The Development of Antiviral Drugs", London, United Kingdom, 18-20 October 1994. |
| "The current prospects for antiviral chemotherapy" (invited lecture). |
| October 1994 |
Seventh International Conference of Comparative and Applied Virology (Virus Diseases, New Surveillance and Control), Montreal, Canada, 12-17 October 1994. |
| -"Therapeutic potential of acyclic nucleoside phosphonates for the treatment of various DNA-virus and retrovirus infections" (invited lecture). |
| -Chairman of Workshop on "Advances in Antiviral Chemotherapy". |
| |
Annual Meeting of the Laboratory of Tumor Cell Biology (National Cancer |
| Institute), Rockville, Maryland, USA, 25 September-1 October 1994. |
| -"How to prevent development of HIV-1 resistance to non-nucleoside HIV-1-specific reverse transcriptase inhibitors" (invited lecture). |
| -"Chairman of Session on Antiviral Therapy (invited). |
| |
Second European Congress of Pharmaceutical Sciences (jointly organized by the |
| European Federation for Pharmaceutical Sciences and the German Pharmaceutical Society), Berlin, Germany, 29 September-1 October 1994. |
| "Trends in drug development for the treatment of AIDS. Compounds interfering with the initial stages of the HIV replicative cycle (invited plenary lecture). |
| September 1994 |
The 4th International Conference on Chemical Synthesis of Antibiotics and Related Microbial Products, Nashville, Brown County, Indiana, USA, 11-16 September 1994. |
| "Therapeutic potential of acyclic nucleoside phosphonates for the treatment of various DNA-virus and retrovirus infections (invited plenary lecture). |
| September 1994 |
Eleventh International Round Table on Nucleosides, Nucleotides and Their Biological Applications, Katholieke Universiteit Leuven (Aula P. De Somer), Leuven, Belgium, 7-11 September 1994. |
| -Organizer of the Round Table. |
| -Welcome remarks. |
| -Concluding remarks. |
| August 1994 |
Tenth International Conference on AIDS (International Conference on STD), Yokohama, Japan, 7-12 August 1994. |
| Moderater (speaker) of Round-Table Session on Protease Inhibitors (invited). |
| July 1994 |
Third European Conference of the Medicinal Chemistry Group of the Atlantic Arc, Cardiff, Wales, United Kingdom, 3-5 July 1994. |
| "Reverse transcriptase inhibitors as anti-HIV agents" (invited plenary lecture). |
| June 1994 |
The Sixth International Antiviral Symposium, Clinical, Pharmacological and Basic Aspects, Acropolis, Nice, France, 7-10 June 1994. |
| - "Chemoprophylaxis and -therapy of acute HIV infections" (invited lecture). |
| - Chairman, Session on "Nucleosides-Chemistry and Biology" (invited). |
| May 1994 |
Fifth International Skin Therapy Symposium, Brussels, Belgium, 25-28 May 1994. |
| "Antiviral therapy in 1994" (invited lecture). |
| May 1994 |
Sixth Cyprus Conference on New Methods in Drug Research, Limassol, Cyprus, 8-14 May 1994. |
| "Recent advances in anti-HIV research" (invited lecture). |
| April 1994 |
Eleventh Future Trends in Chemotherapy Interdisciplinary World Congress on Antimicrobial and Anticancer Drugs, Palexpo, Geneva, Switzerland, 25-27 April 1994. |
| -"Resistance of human immunodeficiency virus type 1 (HIV-1) to non-nucleoside HIV-1-specific reverse transcriptase inhibitors" (invited lecture). |
| -Chairman of the Session on "New Development in Antiviral Chemotherapy" (invited). |
| March 1994 |
The 128th Meeting of the Society for General Microbiology, Clinical Virology Group Symposium on Antiviral Therapy, University of Cambridge, United Kingdom, 28-31 March 1994. |
| "New antivirals" (invited lecture). |
| February-March 1994 |
Seventh International Conference on Antiviral Research, Charleston, South Caro- |
| lina, USA, 27 February - 4 March 1994. |
| -Chairman of Minisymposium on "Viral Pathogenesis: Implications for Antiviral Therapy" (invited). |
| -Participant in Board of Directors' meeting, Officers' meeting, Publications Committee meeting, International Council meeting, Site Selection Committee meeting, Program Committee meeting and Conference Committee meeting of the International Society for Antiviral Research (invited). |
| January 1994 |
Advancing Virology (SmithKline Beecham Pharmaceuticals), Hyde Park Hotel, London, United Kingdom, 14-15 January 1994. |
| "Antiviral chemotherapy in the 21st century" [keynote lecture (invited)]. |
| December 1993 |
In Vitro and Ex Vivo Test Systems to Rationalize Drug Design and Delivery [Assocation de Pharmacie Galénique Industrielle (APGI)/International Pharmaceutical Federation (FIP)], Paris, France, 13-14 December 1993. |
| "In vitro evaluation of antiviral drugs" (invited lecture). |
| August 1993 |
Annual Meeting of the Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA, 22-28 August 1993. |
| -"Therapeutic potential of HIV-1-specific reverse transcriptase inhibitors" (invited lecture). |
| -Chairman of Session on Antiviral Therapy (invited). |
| August 1993 |
International Symposium on Recent Advances in Chemotherapeutic Agents, Research Center for New Drug Development (RCNDD), Seoul National University, Seoul, Korea, 19-20 August 1993. |
| -Overview of new developments of anti-HIV chemotherapy (invited lecture). |
| -Chairman of Session on Antimicrobial/Antiviral Agents (invited). |
| August 1993 |
IXth International Congress of Virology, Glasgow, Scotland, 8-13 August 1993. |
| Chairman of the Workshop on Antiviral Chemotherapy (invited). |
| June 1993 |
Eighteenth International Congress of Chemotherapy, Stockholm, Sweden, 27 June-2 July 1993. |
| "Nucleosides in the chemotherapy of viral infections" invited keynote lecture). |
| June 1993 |
Ninth International Conference on AIDS (Fourth STD World Congress), Berlin, Germany, 7-11 June 1993. |
| Chairman of the Session on Pathogenesis, Therapy and Diagnosis: Antiviral Compounds I (invited). |
| June 1993 |
New York Academy of Sciences Conference on "Slow Infections of the Central Nervous System: The Legacy of Dr. Björn Sigurdsson", Reykjavik, Iceland, 2-5 June 1993. |
| "New developments in the chemotherapy of lentivirus infections" (invited lecture). |
| May 1993 |
Second International FTI (Flanders Technology International) Conference, Ghent, Belgium, 3-6 May 1993. |
| "Towards a cure for AIDS: strategies for the selective inhibition of HIV replication" (invited lecture; host: Prof. Dr. W. Fiers, Director, Laboratory of Molecular Biology, University of Ghent, Belgium). |
| April 1993 |
Sixth International Conference on Antiviral Research, Palazzo Del Cinema, Venice, Italy, 25-30 April 1993. |
| -"Highly selective and potent inhibition of human immunodeficiency virus (HIV) by the novel bicyclam derivative JM3100". |
| -Chairman of the Session on "Retrovirus Infections" (invited). |
| -Directors Board Meeting (International Society for Antiviral Research). |
| -Editorial Board Meeting (journal: Antiviral Research). |
| -Editorial Board Meeting (journal: Antiviral Chemistry and Chemotherapy). |
| April 1993 |
Fourth International Cytomegalovirus Conference on "Multidisci-plinary Approach to Understanding Cytomegalovirus Disease", Paris, France, 18-21 April 1993. |
| Member of the International Organizing Committee, and Chairman of the Sessions on "PCR" and "Antivirals Today" (invited). |
| April 1993 |
World Health Organization (WHO)/Pan American Health Organization (PAHO) Meeting on Antiviral Drug Treatment of Viral Haemorrhagic Fevers, Washington DC, USA, 15-16 April 1993. |
| -Chairman of the Meeting (invited). |
| -"Molecular approaches for the treatment of haemorrhagic fever virus infections" (invited lecture). |
| March 1993 |
Sixth European Congress of Clinical Microbiology and Infectious Diseases, Sevilla, Spain, 28-31 March 1993. |
| -"Sensitivity of viruses to antiviral agents" (invited lecture). |
| -Chairman of Symposium on Antiviral Chemotherapy (invited). |
| March 1993 |
Gordon Conference on "Chemotherapy of AIDS", Casa Sirena Resort, Oxnard, California, USA, 22-26 March 1993. |
| "Targeted action of anti-HIV agents: new advances" (invited introductory lecture). |
| February 1993 |
First Management Forum Conference on AIDS, Development of New Anti-HIV Drugs with Emphasis on Non-Nucleoside Approaches, London, England, 16-17 February 1993. |
| "Anti-HIV drugs which preclude viral entry into susceptible cells" (invited lecture). |
| February 1993 |
"Recherche de Nouvelles Approches Médicamenteuses dans le Domaine du SIDA", Agence Nationale de Recherches sur le SIDA (ANRS), Maison de la Recherche, Paris, France, 10 February 1993. |
| "Implications pour le médicament des nucléosides, des nucléotides et de leurs analogues comme inhibiteurs de la transcriptase inverse" (invited lecture). |
| December 1992 |
Wellcome Symposium in Antiviral Therapy "Innovations in Therapy of Human Viral Diseases", Research Triangle Park, North Carolina, USA, 6-9 December 1992. |
| "Viral target enzymes for nucleotide and nucleoside analogues" (invited lecture). |
| November 1992 |
International Symposium on Research of Antiviral Drugs, Chinese Pharmaceutical Association, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China, 5-7 November 1992. |
| -"Activity spectra and molecular targets of antiviral agents" (plenary invited lecture). |
| -Chairman of session on "Molecular targeting of antiviral agents (invited). |
| October 1992 |
Symposium in Celebration of the Centenary of the Royal Danish School of Pharmacy, Danmarks Farmaceutiske Højskole, Copenhagen, Denmark, 26-29 October 1992. |
| "HIV-1-specific reverse transcriptase inhibitors" (invited lecture). |
| September 1992 |
Tenth International Round Table on Nucleosides, Nucleotides and their Biological Applications, Park City, Utah, USA, 16-20 September 1992. |
| "Therapeutic potential of HPMPC as an antiviral agent" (invited plenary lecture). |
| September 1992 |
Pharmacy World Congress '92 (52nd International Congress of the International Pharmaceutical Federation), Lyon, France, 13-19 September 1992. |
| -"AIDS therapy: AZT and other drugs" (invited lecture). |
| -Chairman of session "Progress in Antiviral Therapy" (invited). |
| August 1992 |
The 204th National Meeting of the American Chemical Society, Washington DC, USA, 23-28 August 1992. |
| "Anti-HIV activity of sulfated polysaccharides" (invited lecture). |
| August 1992 |
Annual Meeting of the Laboratory of Tumor Cell Biology (Chief: Dr. Robert C. Gallo), National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA, 8-15 August 1992. |
| "Specific HIV-1 inhibitors targeted at the HIV-1 reverse transcriptase" (invited lecture). |
| July 1992 |
Fifth World Conference on Clinical Pharmacology and Therapeutics, Yokohama, Japan, 26-31 July 1992. |
| -“Antiviral drugs targeted at DNA synthesis” (special plenary lecture, invited). |
| -“New perspectives for the treatment of HIV infections”, Special Symposium on Strategies to Treat HIV Infection (invited lecture). |
| July 1992 |
Eighth International (Harvard/Amsterdam) Conference on AIDS/Third STD World Congress, Amsterdam, The Netherlands, 19-24 July 1992. |
| -Discussant of Session on "New Antiviral Approaches" (invited). |
| -Chairman of Session on "Protease Inhibitors" (invited). |
| June 1992 |
Fifth International Antiviral Symposium and Second Korean-American AIDS Symposium, Seoul, Korea, 21-25 June 1992. |
| -"Therapeutic potential of acyclic nucleoside phosphonates in the treatment of herpes- and retrovirus infections" (invited lecture). |
| -Chairman of Session "Oligonucleotides" (invited). |
| May 1992 |
Eighth Annual Clinical Virology Symposium (Annual Meeting of the Pan American Group for Rapid Viral Diagnosis), Clearwater Beach, Florida, USA, 17-20 May 1992. |
| "Testing and development of anti-HIV drugs", Whittaker Bioproducts Lectureship (invited lecture). |
| April 1992 |
Benelux Symposium on Diagnosis, Prevention and Therapy of CMV Infections, Breda, The Netherlands, 28 April 1992. |
| "New perspectives for the chemotherapy and prophylaxis of CMV infections" (invited lecture). |
| April 1992 |
Troisième Congrès de la Société Française de Microbiologie, Palais des Congrès, Lyon, France, 21-24 April 1992. |
| "Molecular targets for antiviral agents - Cibles moléculaires des antiviraux" (invited lecture). |
| April 1992 |
Seventh Wartburg Kolloquium des Referenzlaboratoriums für Herpesvirusinfektionen, Paul-Ehrlich-Gesellschaft, Internationale Beteiligung, Eisenach, Germany, 13-16 April 1992. |
| "New perspectives for the treatment of herpesvirus infections (invited lecture). |
| April 1992 |
International Congress on the Management of Infection, RAI Center, Amsterdam, The Netherlands, 5-9 April 1992. |
| "Antivirals for the treatment of herpesvirus infections" (invited lecture). |
| March 1992 |
Tenth Future Trends in Chemotherapy, Interdisciplinary World Congress on Antimicrobial and Anticancer Drugs, Palexpo, Geneva, Switzerland, 30 March-1 April 1992. |
| -"New lead compounds for the treatment of HIV infection (AIDS)" (invited lecture). |
| -Chairman of Session on "Update on Experimental and Clinical Research in Anti-HIV Therapy" (invited). |
| March 1992 |
Gordon Research Conference on the Chemotherapy of AIDS, Oxnard, California, USA, 16-20 March 1992. |
| Discussion Leader (Chairman) of Session on "Non-nucleoside anti-HIV drugs" (invited). |
| March 1992 |
Fifth International Conference on Antiviral Research, Vancouver, British Columbia, Canada, 8-13 March 1992. |
| -Welcome remarks. |
| -"Potent and selective inhibition of HIV-1 and HIV-2 replication by a novel class of bicyclams targeted at viral uncoating". |
| -Business remarks on the International Society for Antiviral Research. |
| -Chairman of Minisymposium on "New horizons in antiviral research" (invited). |
| January 1992 |
EORTC International Antimicrobial Therapy Cooperative Group Meeting (34th Working Meeting), Institut Jules Bordet, Brussels, Belgium, 8-9 January 1992. |
| "New anti-herpesvirus drugs under development" (invited lecture). |
| November 1991 |
Program Committee Meeting for the Vth International Conference on Antiviral Research (Vancouver, Canada, 8-13 March 1992), Bethesda, Maryland, USA, 21-22 November 1991. |
| November 1991 |
Meeting on "Combination Therapics in AIDS: Issues and Perspectives", organized by the Food and Drug Administration (FDA) and National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, USA, 19-21 November 1991. |
| -Ribavirin and anti-HIV nucleoside analogs: drug interactions (invited lecture). |
| -Chairman of session "In vitro experimental models for evaluating combination drug therapics" (invited). |
| -Panel discussion on "Transition of preclinical studies to clinical applications". |
| November 1991 |
First Meeting of the Pediatric European Network for Treatment of AIDS in HIV-Infected Children (PENTA), Maison de la Recherche, Association Internationale pour la Recherche Médicale (AIRMEC), Paris, France, 15-16 November 1991. |
| "Development of anti-HIV drugs" (invited lecture). |
| September 1991 |
Cinquièmes Journées Franco-Belges de Pharmacochimie, Institut de Chimie Pharmaceutique de l'Université de Lille II, Lille, France, 26-27 September 1991. |
| "Nouvelles acquisitions dans le domaine des antiviraux" (invited lecture). |
| September 1991 |
X Summer Courses, III European Courses, Cursos de Verano en San Sebastian, Donostian Udako Ikastaroak. SIDA: Un Desafio Para La Sociedad, San Sebastian, Spain, 2-6 September 1991. |
| "Perspectives for the treatment of AIDS" (invited lecture). |
| September 1991 |
The Alfred Benzon Symposium no 33 on "New Leads and Targets in Drug Research", Royal Danish Academy of Sciences and Letters, Copenhagen, Denmark, 1-5 September 1991. |
| "Novel molecular target for AIDS chemotherapy" (invited lecture). |
| July 1991 |
Gordon Research Conference on Purines, Pyrimidines and Related Compounds, Salve Regina College, Newport, Rhode Island, USA, 8-12 July 1991. |
| "Antiretroviral activity and metabolism of acyclic phosphonate analogues" (invited lecture, jointly with and delegated to J. Balzarini). |
| June 1991 |
Third International Symposium on Molecular Aspects of Chemotherapy, Gdansk, Poland, 19-21 June 1991. |
| "Anti-HIV agents interfering with the viral gp120-cellular CD4 interaction" (invited lecture, delegated to D. Schols). |
| June 1991 |
Seventh International Conference on AIDS, Florence, Italy, 16-21 June 1991. |
| Chairman, Session on Drug Development (invited, delegated to J. Balzarini). |
| June 1991 |
International Symposium on Antiviral, Vaccines and Immunotherapy of HIV Infection, St. Petersburg, Florida, USA, 31 May - 2 June 1991. |
| -"Perspectives for the therapeutic use of acyclic nucleoside phosphonates" (invited lecture). |
| -Chairman of "Antiviral Drugs" Session (invited). |
| May 1991 |
Fifth International Conference on Immunopharmacology, Tampa, Florida, USA, 26-30 May 1991. |
| -"Prospects with antiviral therapy" (invited lecture). |
| -Chairman of the Session on AIDS (invited). |
| May 1991 |
New York Academy of Sciences, Biochemical Pharmacology Discussion Group, New York, New York, 21 May 1991. |
| "Non-nucleoside (TIBO, HEPT) inhibitors of HIV-1 reverse transcriptase" (invited lecture). |
| May 1991 |
GESA XXI (Groupe d'Etude Structure Activité), La Rochelle, France, 14-17 May 1991. |
| -"Récents développements en chimiothérapie antivirale" (invited lecture). |
| -Chairman of Session on Anti-infective Chemotherapy (invited). |
| May 1991 |
First European Medicinal Chemistry Conference (MedChemCo), Erbismühle, Weilrod-Neuweilnau, Germany, 8-12 May 1991. |
| -"New leads toward the chemotherapy of retrovirus (human immunodeficiency virus) infections" (invited lecture). |
| -Chairman of the session "HIV-Retroviruses" (invited). |
| April 1991 |
Fourth International Conference on Antiviral Research, New Orleans, Louisiana, USA, 21-26 April 1991. |
| -"Opening remarks" (as President of the International Society for Antiviral Research). |
| -"Structure and functioning of the International Society for Antiviral Research". |
| -Chairman of Minisymposium on Molecular Targets for Antiviral Agents. |
| -Meetings of the Board of Directors, the Officers and the International Advisory Committee of the International Society for Antiviral Research. |
| -Editorial Board Meeting of the Journal "Antiviral Research". |
| -Editorial Board Meeting of the Journal "Antiviral Chemistry and Chemotherapy". |
| -Meeting of the Program Committee of the Fifth International Conference on Antiviral Research (to be held in Vancouver, Canada, 8-13 March 1992). |
| March 1991 |
International Conference on "Antiviral Drugs: From the Laboratory to the Patient", IBC (International Business Communications) Technical Services, London, England, 11-12 March 1991. |
| -Chairman of the Conference (invited). |
| -"Antiviral drug development - New lead compounds" (invited lecture). |
| March 1991 |
I Congreso Nacional Sobre el Sida, Madrid, Spain, 5-8 March 1991. |
| "New developments in the search for effective anti-AIDS drugs" (invited lecture) (host: Dr. R. Najera Morrondo, Director del Instituto de Salud Carlos III del Ministerio de Sanidad y Consuma, Madrid). |
| February 1991 |
WHO (World Health Organization) Scientific Meeting on Factors for Progression to AIDS: Intracellular Pathogenic Mechanisms Offering Opportunities for Therapeutic Interventions, Geneva, Switzerland, 18 February 1991. |
| -"TIBO and other non-nucleoside RT-inhibitors" (invited lecture). |
| -Chairman of the Meeting (invited). |
| Consulting Meeting with Dr. H. Nakajima, Director-General of WHO (World Health Organization), on Anti-AIDS Drug Development and Infectious Co-Factors in AIDS (host: Prof. Dr. L. Kallings, WHO Global Progamme on AIDS). |
| November 1990 |
XVes Journées d'Orléans "Virus et Rétrovirus: Perspectives Thérapeutiques", Université d'Orléans, Orléans-La Source, France, 29-30 November 1990. |
| "Nouvelles acquisitions dans le domaine de la chimiothérapie antivirale" (invited lecture). |
| October 1990 |
Workshop on Viral Resistance, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) and Food and Drug Administration (FDA), Washington DC, USA, 1-2 October 1990. |
| Chairman (together with Prof. Dr. B. Roizman) of Session on In Vitro Studies (invited). |
| September 1990 |
Fourth Joint Meeting of the Biochemical Societies of France, Switzerland and Germany, Konstanz, Germany, 17-19 September 1990. |
| "Antiviral activity of acyclic nucleotide analogues" (invited lecture). |
| August 1990 |
Eighth International Congress of Virology, Berlin, Germany, 26-31 August 1990. |
| Chairman, Workshop on Antiviral Drugs (invited). |
| July-August 1990 |
The Amsterdam International Medical Summer School on "Recent Advances in |
| Immunology and Infectious Diseases", Faculty of Medicine, University of Amsterdam, Amsterdam, The Netherlands, 16 July - 10 August 1990. |
| "State of the art of antiviral treatment" (invited lecture). |
| July-August 1990 |
Ninth International Round Table on Nucleosides, Nucleotides & their Biological |
| Applications, Uppsala, Sweden, 30 July - 3 August 1990. |
| "Antiviral activity spectrum of nucleoside and nucleotide analogues" (invited plenary lecture). |
| July 1990 |
Molecular Approaches to the Therapy of HIV Infection, Society for Drug Research Meeting, Robinson College, Cambridge, England, 9-11 July 1990. |
| "In vitro evaluation of anti-HIV-1 compounds" (invited lecture). |
| July 1990 |
Les 26èmes Rencontres Internationales de Chimie Thérapeutique, Société de Chimie Thérapeutique, Faculté de Pharmacie, Montpellier, France, 3-5 July 1990. |
| "Strategies in the development of selective antiviral agents" (invited lecture). |
| June 1990 |
Sixth International Conference on AIDS, San Francisco, California, USA, 20-24 June 1990. |
| "Basic approaches to anti-retroviral treatment" (invited plenary lecture). |
| May 1990 |
European Course on Hospital Antimicrobial Chemotherapy, Fondation Mérieux, Les Pensières, Chavoires, Veyrier-du-Lac, Annecy, France, 23 May - 3 June 1990. |
| "Mechanisms of action of and resistance to antiviral drugs" (invited lecture). |
| May 1990 |
Seventh Mediterranean Congress of Chemotherapy, Symposium on "Viral Infections: Therapeutic Perspectives", Barcelona, Spain, 20-25 May 1990. |
| "New anti-HIV drugs" (invited lecture). |
| May 1990 |
Third International Skin Therapy Symposium, Brussels, Belgium, 17-19 May 1990 (President: Prof. Dr. Stuart Maddin, University of British Columbia, Vancouver, Canada). |
| "Varicella-zoster virus infections: current drugs of choice" (invited lecture). |
| May 1990 |
Voorjaarsvergadering van de Nederlandse Vereniging voor Microbiologie, Nederlandse Vereniging van Laboratorium-artsen, de Medigon-Werkgemeenschap "Microbiële Pathogenese" en de Stichting Kwaliteitsbewaking Medische Microbiologie, De Blije Werelt, Lunteren, The Netherlands, 16-17 May 1990. |
| "Antivirale chemotherapie" (invited lecture). |
| May 1990 |
Janssen Research Foundation Bio-Science Advisory Committee Meeting on "Progress in the Treatment of the Common Cold and AIDS", Beerse, Belgium, 15-16 May 1990. |
| "Molecular targets for antiviral compounds, and in particular anti-HIV compounds" (invited lecture). |
| May 1990 |
Seventh World Congress of Cervical Pathology and Colposcopy, Special Symposium on Chemoprevention and Antiviral Chemotherapy, Rome, Italy, 13-17 May 1990. |
| "New perspectives for the chemotherapy of herpes- and retrovirus infections" (invited lecture). |
| April 1990 |
Third International Conference on Antiviral Research, Brussels, Belgium, 22-27 April 1990. |
| -Organizer of the Conference. |
| -Chairman of the Minisymposium on HIV infections. |
| -Opening remarks. |
| -Closing remarks. |
| April 1990 |
Second National Congress of Virology (II Congreso Nacional de Virologia), Sociedad Espanola de Virologia, Valladolid, Spain, 17-20 April 1990. |
| -"Antiviral therapy of herpesvirus infections" (invited lecture). |
| -"Antiviral therapy of retrovirus infections" (invited lecture). |
| -Chairman of Session on Advances in Antiviral Therapy (invited). |
| -Chairman of Session on AIDS (invited). |
| March 1990 |
Ninth International Symposium on Future Trends in Chemotherapy, Geneva, Switzerland, 26-28 March 1990. |
| -"Future trends in antiviral chemotherapy" (invited plenary lecture). |
| -Chairman of Session on Antivirals (invited). |
| March 1990 |
Eleventh Kongress der Gesellschaft für Mikrobiologie und Epidemiologie der DDR (mit internationaler Beteiligung), Erfurt, DDR, 5-9 March 1990. |
| -"Recent developments in the search for effective anti-AIDS drugs" (invited lecture). |
| -Chairman of session on "Antiviral Chemotherapy" (invited). |
| January 1990 |
First Japan Conference on Antiviral Research, Japan Society for Antiviral Research, Tokyo, Japan, 19-20 January 1990. |
| "Development of selective anti-HIV agents" (invited plenary lecture). |
| November 1989 |
Fourth International Conference "To Life: Why", Pontificium Consilium de Apostolatu Pro Valetudinis Administris, Vatican City, 13-15 November 1989. |
| "Prospects for antiviral drugs in the treatment of human retrovirus infections" (invited lecture). |
| October 1989 |
International Symposium on Antiviral Chemotherapy, Porto Cervo, Sardinia, Italy, 1-5 October 1989. |
| -"Approaches toward the chemotherapy of AIDS" (invited lecture). |
| -Chairman of the Session on "Chemistry of Antiviral Agents" (invited). |
| -Member of Organizing Committee. |
| September 1989 |
Institut de la Vie International Symposium on "Biomedical Research Strategy on AIDS", Yverdon-Les-Bains, Switzerland, 24-28 September 1989. |
| -"New developments in the search for effective anti-AIDS drugs" (invited lecture). |
| -Chairman of the Session on "Antiviral Therapy" (invited). |
| September 1989 |
Herbsttagung, Deutsche Gesellschaft für Pharmakologie und Toxikologie, Symposium "Gegenwärtige Schwerpunkte der antimikrobiellen Arzneimittelforschung", Köln, Federal Republic of Germany, 18-21 September 1989. |
| "Molecular targets for new anti-HIV agents" (invited lecture). |
| September 1989 |
Seventh Noordwijkerhout-Camerino Symposium on "Trends in Drug Research", Noordwijkerhout, The Netherlands, 5-8 September 1989. |
| "New developments in anti-AIDS drug research" (invited lecture). |
| August 1989 |
BMC (Biomedical Center) Summer Course on "Current Status of HIV Research", Uppsala, Sweden, 13-18 August 1989. |
| "New perspectives in the chemotherapy of AIDS" (invited lecture). |
| July 1989 |
Fourth World Conference on Clinical Pharmacology and Therapeutics, Mannheim-Heidelberg, Federal Republic of Germany, 23-28 July 1989. |
| -"Fundamental aspects of anti-AIDS chemotherapy" (invited lecture). |
| -Chairman of the Symposium on "AIDS: approaches to control and treatment strategies" (invited). |
| July 1989 |
Sixth AIDS Clinical Trials Group (ACTG) Meeting, AIDS Program of the National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA, 12-14 July 1989. |
| "New anti-HIV compounds as potential AIDS drugs" (invited plenary lecture). |
| April 1989 |
Symposium on Biochemical Aspects of Antiviral Drugs and Vaccines (113th Ordinary Meeting of the Society for General Microbiology), University of Cambridge, England, 4-7 April 1989. |
| "Approaches to chemotherapy of HIV infection" (invited lecture). |
| March-April 1989 |
Fourth International Symposium on Clinical Microbiology, organized by the |
| First University of Rome "La Sapienza" and the Second University of Rome "Tor Vergata", Monte Porzio Catone (near Rome), Italy, 30 March-1 April 1989. |
| -"Chemotherapy of viral infections in immunocompromised patients" (invited lecture). |
| -Chairman of Session on Viral Infections (invited). |
| March 1989 |
Second Biennial Conference on Chemotherapy of Infectious Diseases and Malignancies, Montreux, Switzer-land, 5-8 March 1989. |
| -"Chemotherapeutic approaches towards virus infections" (invited lecture). |
| -Chairman of Symposium on "Virology" (invited). |
| October-November 1988 |
NIH (National Institutes of Health) AIDS National Cooperative Drug Discovery |
| and Development Meeting, Oakland, California, USA, 30 October-2 November 1988. |
| Invited participant. |
| October 1988 |
International Symposium on AIDS, San Marino Conferences on Hightlights in Medical Virology, Immunology and Oncology (Chairman : Prof. Dr. R.C. Gallo), San Marino, 10-14 October 1988. |
| -"New anti-HIV agents and potential drugs for the treatment of AIDS" (invited lecture). |
| -Chairman of the Session on "Antivirals" (invited). |
| October 1988 |
International Titisee Conference on Antiretroviral Chemotherapy, Titisee, Schwarzwald, Federal Republic of Germany, 6-9 October 1988. |
| "Role of reverse transcription inhibition in the mechanism of action of anti-HIV agents" (invited lecture). |
| October 1988 |
Eighth International Round Table on Nucleosides, Nucleotides and their Biological Applications, Perdido Beach Hilton, Orange Beach, Alabama, USA, 2-5 October 1988. |
| "Anti-HIV activity of nucleoside and nucleotide analogues" (invited plenary lecture). |
| September 1988 |
Working Party on New Therapeutic Protocols for the Treatment of H.I.V. Infection, European Federation for AIDS Research (Chairman : Prof. Dr. L. Montagnier), Paris, France, 26 September 1988. |
| "Overview of the Antivirals" (invited lecture). |
| August 1988 |
Bayer AG Centenary Symposium, Washington, D.C., 31 August-3 September 1988. |
| "Molecular targets for antiviral agents" (invited lecture). |
| August 1988 |
Nineteenth International Congress of Internal Medicine, Brussels, Belgium, 28. August-2 September 1988. |
| "Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome" (invited lecture). |
| August 1988 |
Tenth International Symposium on Medicinal Chemistry, Budapest, Hungary, 15-19 August 1988. |
| -"New antiviral agents active against the AIDS virus" (invited lecture). |
| -Chairman of a Session (invited). |
| July 1988 |
Fourteenth International Congress of Biochemisry, Prague, Czechoslovakia, 10-15 July 1988. |
| "Antiviral activity of new nucleoside and nucleotide analogues" (invited lecture). |
| June 1988 |
International Symposium on Basic and Clinical Approaches to Virus Chemotherapy, Helsinki, Finland, 19-22 June 1988. |
| "New antiviral agents with potential usefulness in the chemotherapy of AIDS" (invited lecture). |
| June 1988 |
Fourth International Conference on AIDS, Stockholm, Sweden, 12-16 June 1988. |
| Chairman of the Round Table on "Developments in Antiviral Therapy" (invited). |
| June 1988 |
Twenty-second Villejuif-Paris International Cancer Week (Organizer : Prof. G. Mathé), Symposium on Cancer and AIDS, Antiviral, Hormonal, Nutritional and Immunotherapy, Paris, France, 8-9 June 1988. |
| -"New dideoxynucleoside analogues" (invited lecture). |
| -"Sulfated polysaccharides" (invited lecture). |
| May 1988 |
Sixth Mediterranean Congress of Chemotherapy, Taormina-Giardini Naxos, Italy, 22-27 May 1988. |
| -"Inhibition of the replication of DNA viruses by phosphonyl- methoxyalkylpurines and -pyrimidines" (invited lecture). |
| -"Perspectives for the chemotherapy of AIDS" (invited lecture). |
| -"Antiviral chemotherapy : past, present and future" (invited lecture). |
| -Chairman of the Session on "Infections in Immunocompromised Patients" (invited). |
| -Chairman of the Session on "Antiviral Chemotherapy" (invited). |
| May 1988 |
Second International Skin Therapy Symposium, Antwerp, Belgium, 5-7 May 1988. |
| "New antiviral agents for herpes simplex/herpes zoster" (invited lecture). |
| April 1988 |
International Symposium on Present Development of HIV Research in 1988, IRE-Medgenix Benelux, Brussels, Belgium, 29 April 1988. |
| "Selective inhibitors of HIV" (invited lecture). |
| April 1988 |
British Society for Antimicrobial Chemotherapy (BSAC) Meeting on Therapy of HIV and AIDS-related Infections, Stratford upon Avon, England, 21-22 April 1988. |
| "Potential for future developments in drug therapy of HIV infection" (invited lecture). |
| April 1988 |
International Meeting on Treatment of AIDS, Genval, Belgium, 20-21 April 1988. |
| "Antiviral agents against AIDS virus" (invited lecture). |
| April 1988 |
Second International Conference on Antiviral Research, Williamsburg, Virginia, USA, 10-14 April 1988. |
| "Development of nucleoside analogs for inhibition of HIV replication" (invited plenary lecture). |
| March 1988 |
Second International Conference on the Impact of Viral Diseases on the Development of Latin American Countries and the Caribbean Region, Mar del Plata, Argentina, 20-25 March 1988. |
| -"Chemotherapy of DNA virus and retrovirus infections" (invited lecture). |
| -Chairman of the Workshop on "Antiviral Chemotherapy and Immunomodulators" (invited). |
| March 1988 |
Gordon Research Conference on Chemotherapy of AIDS, Oxnard, California, USA, 14-18 March 1988. |
| "Anti-HIV activity of 3'-azido- and 3'-fluoro-substituted 2',3'-dideoxynucleoside analogues, and phosphonylmethoxyalkylpurine and -pyrimidine derivatives" (invited lecture). |
| January 1988 |
Symposium on Treatment of Virus Infections (110th Ordinary Meeting of the Society for General Microbiology), Southampton, England, 6-8 January 1988. |
| "Chemical basis of antiviral action" (invited lecture). |
| December 1987 |
Twentieth Anniversary Nucleotide Group Meeting Celebrating 40 Years of Nucleic Acids Research at Birmingham University, Chemistry Department, Birmingham University, Birmingham, England, 14-16 December 1987. |
| "Antiviral chemotherapy : a renaissance" (invited lecture). |
| December 1987 |
AIDS Retreat, Sandoz Forschungsinstitut, Vienna, Austria, 12-14 December 1987. |
| -"Inhibitors of HIV (Human Immunodeficiency Virus) reverse transcriptase" (invited lecture). |
| -Discussion on the Use of Animal Models for Retrovirus Infection (invited). |
| December 1987 |
The Wellcome International Antiviral Symposium, Monte-Carlo, Monaco, 2-4 December 1987. |
| Chairman of the Session on Varicella Zoster Infections (invited). |
| November 1987 |
Colloque INSERM (Institut National de la Santé et de la Recherche Médicale) - SNIP (Syndicat National de l'Industrie Pharmaceutique) sur les "Nouvelles Approches en Chimiothérapie Antivirale", Ministère de la Recherche et de l'Enseignement Supérieur, Paris, France, 20 November 1987. |
| "Inhibiteurs des polymérases virales" (invited lecture). |
| November 1987 |
Annual Meeting of the Virology Section of the Société Française de Microbiologie sur "La Chimiothérapie Antivirale", Institut Pasteur, Paris, France, 19 November 1987. |
| "Développements récents dans le domaine de la chimiothérapie antivirale" (invited lecture). |
| October 1987 |
First International Workshop on New Perspectives in Cancer Research, Halkis, Greece, 15-18 October 1987. |
| -"Perspectives for the chemotherapy of AIDS" (invited lecture). |
| -Chairman of Session 3 of the Workshop (invited). |
| October 1987 |
Seventh International Symposium of the Socialist Countries on Antiviral Substances, Bulgarian Academy of Sciences, Varna, Bulgaria, 12-14 October 1987. |
| -"New developments in antiviral chemotherapy" (invited lecture). |
| -Chairman of the Session on "Methods of Experimental Chemotherapy of Viral Infections" (invited). |
| September-October 1987 |
Second Séminaire d'Automne de Troisième Cycle en Sciences Pharmaceutiques, |
| Champéry, Switzerland, 28 September-2 October 1987. |
| -"Analogues de nucléosides et de nucléotides comme agents antiviraux" (invited lecture). |
| -Modérateur (Chairman) de la Table Ronde sur le Métabolisme des Médicaments (Drug Metabolism) (invited). |
| September 1987 |
International Symposium on Basic and Therapeutic Aspects of Antiviral Drugs, Copanello (Catanzaro), Italy, 17-19 September 1987. |
| -"Viral DNA polymerases as targets for the antiviral action of nucleoside analogues" (invited lecture). |
| -Session Chairman at the Symposium (invited). |
| September 1987 |
International Congress on Nucleic Acid Interactions, University of Padova, Villa Contarini, Padova, Italy, 13-17 September 1987. |
| "Mechanism of action of antiviral agents : interactions with DNA and with DNA polymerase" (invited lecture). |
| September 1987 |
EC (European Community) AIDS Basic Research Programme Meeting on Coordination of Research on Antiviral Drug Development against AIDS, Leuven, Belgium, 10 September 1987. |
| Chairman of the Meeting. |
| August 1987 |
Tenth International Congress of Pharmacology, Sydney, Australia, 23-28 August 1987. |
| -"Strategies in the development of antiviral agents" (invited plenary lecture). |
| -Chairman of the Symposium on "New Approaches to Antiviral Chemothe-rapy" (invited). |
| -"Introductory remarks" to Symposium on "New Approaches to Antiviral Chemotherapy". |
| -“Comments on new antiviral agents active against the AIDS virus" (Symposium on "New Approaches to Antiviral Chemotherapy"). |
| July 1987 |
Fifteenth International Congress of Chemotherapy, Istanbul, Turkey, 19-24 July 1987. |
| "Phosphonylmethoxyalkylpurines and -pyrimidines : a new class of broad-spectrum anti-DNA virus agents" (invited lecture). |
| June-July 1987 |
Eighteenth FEBS (Federation of European Biochemical Societies) Meeting, Ljubljana, Yugoslavia, 28 June-3 July 1987. |
| -"Biochemistry of antiviral agents" (invited lecture). |
| -Chairman of the Session on "Biochemical Approaches to Therapy of Viral Diseases" (invited). |
| June 1987 |
Third International Conference on AIDS, Washington, D.C., USA, 1-5 June 1987. |
| Chairman of the Session on "Virology - Antivirals" (invited). |
| May 1987 |
NATO Advanced Study Institute/FEBS Advanced Course on Antiviral Drug Development : A Multidisciplinary Approach, Il Ciocco, Italy, 10-23 May 1987. |
| -"Molecular targets : general principles" (invited lecture). |
| -Organizer, Director and Chairman of the NATO/FEBS Course. |
| May 1987 |
Fifth Annual ECP (European Organization for Cooperation in Cancer Prevention Studies) Symposium, Brussels, Belgium, 8-9 May 1987. |
| -"Phosphonylmethoxyalkyl derivatives of purines and pyrimidines : a new class of antiviral agents active against both herpesviruses and retroviruses" (invited lecture). |
| -Member of the Scientific Committee. |
| May 1987 |
Nineth European Conference of Internal Medicine, Bologna, Italy, 6-9 May 1987. |
| "Viral chemotherapy" (invited lecture). |
| March 1987 |
WHO (World Health Organization) Meeting on Progress in Development and Use of Antiviral Drugs and Interferons, Geneva, Switzerland, 10-13 March 1987. |
| -”New developments in antiviral chemotherapy" (invited lecture). |
| -Chairman of the Meeting (elected). |
| March 1987 |
Seventh International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 3-6 March 1987. |
| "Antiviral chemotherapy : potential drugs for the treatment of severe virus infections" (invited lecture). |
| November 1986 |
International Symposium on Frontiers in Microbiology (dedicated to the memory of Prof. Dr. P. De Somer), Katholieke Universiteit Leuven, 20-22 November 1986. |
| -Chairman of the Organizing Committee. |
| -Chairman of the Session on "New Horizons in Virus Research", with an introductory lecture to this session. |
| September- October 1986 |
Seventh International Round Table on Nucleosides, Nucleotides and their Biolo- |
| gical Applications, Konstanz, Federal Republic of Germany, 30 September-3 October 1986 (Organizer : Prof. Dr. W. Pfleiderer). |
| "New nucleoside and nucleotide analogues with therapeutic potential as antiviral agents" (invited plenary lecture). |
| September 1986 |
Fifth CHEMRAWN (Chemical Research Applied to World Needs) Conference on "Current and Future Contributions of Chemistry to Health - The New Frontiers", Heidelberg, Federal Republic of Germany, 22-26 September 1986. |
| -"Recent trends and developments in antiviral chemotherapy" (invited lecture). |
| -Participant in Panel Discussion on "Perspectives of Antibacterial, Antimycotic and Antiviral Chemotherapy" (invited). |
| September 1986 |
Third International Symposium of Clinical Microbiology, Spoleto, Italy, 18-20 September 1986. |
| -"Virus-drug resistance" (invited lecture). |
| -Chairman of the Session on "Virus Infections" (invited). |
| September 1986 |
Ninth International Symposium on Medicinal Chemistry, Berlin (West), Federal Republic of Germany, 14-18 September 1986. |
| "New antiviral agents" (invited main lecture). |
| July-August 1986 |
Third World Conference on Clinical Pharmacology and Therapeutics, Stockholm, Sweden, 27 July-1 August 1986. |
| -"New developments in antiviral chemotherapy" (invited lecture). |
| -Chairman and Organizer of the Symposium on "Clinical Use of Antiviral Drugs" (invited). |
| July 1986 |
Ninth International Congress of Infectious and Parasitic Diseases, Munich, Federal Republic of Germany, 20-26 July 1986. |
| "Antiviral chemotherapy : acquired immune deficiency syndrome (AIDS)" (invited lecture). |
| July 1986 |
Second Congress of the Mediterranean Society of Therapy, Istanbul, Turkey, 20-25 July 1986. |
| "Antiviral drugs active against DNA viruses" (invited lecture). |
| June 1986 |
Antibiotics 86 Meeting, Granada, Spain, 19-24 June 1986. |
| "Nucleoside analogues as antiviral agents" (invited lecture). |
| May 1986 |
Fifth International Conference on Comparative Virology, Château Lake Louise, Alberta, Canada, 4-9 May 1986. |
| -"Nucleoside analogues in the chemotherapy of virus infections" (invited plenary lecture). |
| -Chairman of the Session on "Antiviral Chemotherapy" (invited). |
| April 1986 |
Third Meeting on Bioorganic Chemistry of the Czechoslovak Chemical Society, Liblice, Czechoslovakia, 21-23 April 1986. |
| -"Recent approaches toward the development of new antiviral agents" (invited lecture). |
| -Chairman of the Session on "Synthetic Nucleoside Analogues in Biology and Medicine" (invited). |
| April 1986 |
Seventienth Annual Meeting of the Federation of American Societies for Experimental Biology (FASEB), St. Louis, Missouri, USA, 13-18 April 1986. |
| Symposium on Antiviral Chemotherapy of Herpes, Influenza and AIDS, Biochemical and Clinical Pharmacology (Organizer : Prof. Dr. P.S. Lietman). |
| "Suramin in the treatment of AIDS : mechanism of action" (invited lecture). |
| October 1985 |
First International Conference of Anticancer Research, Loutraki, Greece, 26-30 October 1985. |
| "Potential of bromovinyldeoxyuridine in anticancer chemotherapy". |
| September 1985 |
International Symposium on Antiviral Drugs, sponsored by the American Institute of Chemists, Chicago, Illinois, USA, 18-20 September 1985. |
| "The development of bromovinyldeoxyuridine" (invited lecture). |
| September 1985 |
Thirty-eighth Symposium of the Society for General Microbiology on the Scientific Basis of Antimicrobial Chemotherapy (104th Ordinary Meeting of the Society for General Microbiology), Nottingham, England, 16-19 September 1985. |
| "Antiviral agents" (invited lecture). |
| August 1985 |
Second International Conference on Synthetic Oligonucleotides in Molecular Biology, Uppsala University, Sweden, 18-24 August 1985. |
| -"Nucleoside analogues as potential antiviral and antitumor agents" (invited lecture). |
| -Chairman of Session (invited). |
| June 1985 |
Symposium on Prevention and Treatment of Viral Infections, Bechyne Castle, Czechoslovakia, 17-19 June 1985. |
| -"New trends in the development of antiviral agents" (invited opening lecture). |
| -Chairman of the Session on "Antivirals and Chemotherapy" (invited). |
| June 1985 |
AIDS Antiviral Agent Workshop, Public Health Service, National Institutes of Health, Bethesda, Maryland, USA, 3 June 1985. |
| Discussion on the use of suramin and other reverse transcriptase inhibitors in the treatment of patients with AIDS ("Acquired Immune Deficiency Syndrome") (invited). |
| May 1985 |
European Symposium on Bio-organic Chemistry (ESBOC), Nucleosides and Nucleotides in Nature, Gregynog, University of Wales, Wales, United Kingdom, 17-20 May 1985. |
| "Carbocyclic analogues of pyrimidine nucleosides: metabolism by and incorporation into DNA of herpes simplex virus-infected cells" (invited lecture). |
| May 1985 |
International Meeting on Advances in Virology, Catania, Italy, 15-18 May 1985. |
| -"Selective inhibitors of viral functions" (invited plenary lecture). |
| -Chairman of Session on "Problems in Viral Chemotherapy" (invited). |
| May 1985 |
First International TNO Conference on Antiviral Research (Netherlands Organization of Applied Scientific Research), Rotterdam, The Netherlands, 30 April-3 May 1985. |
| -"Recent trends and developments in antiviral chemotherapy" (invited lecture). |
| -Chairman of the Session on "Antiviral Chemotherapy" (invited). |
| -Member of the Organizing Committee. |
| April 1985 |
Negentiende Vergadering van de Vereniging voor Infectieziekten, Andreas Ziekenhuis, Amsterdam, The Netherlands, 26-27 April 1985. |
| "Antiviral therapy: bromovinyldeoxyuridine/guanosine analogues" (invited lecture). |
| March 1985 |
Symposium on Infections in Tumor Patients (Organizer: Prof. Dr. U. Jehn), Medizinische Klinik III, Klinikum Grosshadern (Director : Prof. Dr. W. Wilmanns), München, Federal Republic of Germany, 30 March 1985. |
| "Problems and new aspects of antiviral treatment" (invited lecture). |
| January 1985 |
Symposium on Chemotherapy of Herpesvirus Infections (Organizer: Prof. Dr. H. Kirchner, Institute of Virus Research, German Cancer Research Center), Heidelberg, Federal Republic of Germany, 12 January 1985. |
| "General aspects of antiherpetic chemotherapy" (invited lecture). |
| October 1984 |
Sixth International Round Table on Nucleosides, Nucleotides and their Biological Applications, La Grande Motte (Montpellier), France, 9-12 October 1984. |
| -"Targets for the antiviral and antitumor activities of nucleoside, nucleotide and oligonucleotide analogues" (invited plenary lecture). |
| -Chairman of the Communication Session (invited). |
| September 1984 |
International Symposium on Pharmacological and Clinical Approaches to Herpes Viruses and Virus Chemotherapy, Oiso, Japan, 10-13 September 1984. |
| -"Clinical potentials of BVDU (bromovinyldeoxyuridine)" (invited lecture). |
| -Chairman of the Session on "Clinical Experience with New Antiherpetic Compounds in Genital and Systemic Diseases" (invited). |
| September 1984 |
Eleventh Symposium on Developmental Pharmacology (Organizer : Prof. Dr. T. Fujimoto), Nagoya, Japan, 7-8 September 1984. |
| "Potentials of antiherpes agents in the treatment of herpesvirus infections in children with cancer" (invited lecture). |
| September 1984 |
Sixth International Congress of Virology, Sendai, Japan, 1-7 September 1984. |
| -"Regeneration of the antiviral drug bromovinyldeoxyuridine from its degradation product bromovinyluracil" (invited lecture). |
| -Chairman of the Workshop T-34 on "Therapy of Virus Diseases; Antiviral Compounds" (invited). |
| August 1984 |
Eighth International Symposium on Medicinal Chemistry, Biomedical Center, University of Uppsala, Uppsala, Sweden, 27-31 August, 1984. |
| "Bromovinyluracil nucleoside analogues as antiherpes agents" (invited lecture). |
| July-August 1984 |
Ninth International Congress of Pharmacology, London, England, 29 July-3 August 1984. |
| "Modes of action of interferon and analogues of 2-5A, a mediator of interferon action" (invited lecture). |
| July 1984 |
Gordon Research Conference on Purines, Pyrimidines and Related Compounds, Plymouth State College, New Hampshire, USA, 23-27 July 1984. |
| "Biochemistry of new antiviral compounds" (invited lecture). |
| May 1984 |
International Symposium on Antimicrobial Agents and Immunity (Organizers : Prof. Dr. J. Jeljaszewicz & Prof. Dr. G. Pulverer), Heppenheim, Federal Republic of Germany, 23-27 May 1984. |
| "Antiviral agents and immune system" (invited lecture). |
| May 1984 |
International Symposium on Herpetic Eye Diseases, Leuven, Belgium, 17-19 May 1984. |
| -"New antiviral drugs for the treatment of herpesvirus infections" (invited lecture). |
| -Chairman at the Symposium (invited). |
| April 1984 |
UCLA Symposia on Molecular and Cellular Biology, Burroughs Wellcome Company UCLA Symposium on Herpesvirus, Keystone, Colorado, USA, 8-13 April 1984. |
| -"Comparative efficacy of different antiviral agents in the topical treatment of cutaneous HSV-1 and HSV-2 infections in hairless mice" (invited lecture). |
| -"Therapeutic potentials of bromovinyldeoxyuridine (BVDU) in the treatment of herpesvirus infections" (invited lecture). |
| January 1984 |
Symposium on Biology, Diagnosis and Specific Treatment of Infections caused by the Herpes Group of Viruses, Lääketiede 1984 Medicine Congress, Helsinki, Finland, 9-10 January 1984. |
| "Promises and failures of antiviral chemotherapy" (invited lecture). |
| December 1983 |
Fourth Virology Meeting of the British Society for Antimicrobial Chemotherapy, New Addenbrooke's Hospital, University of Cambridge, Cambridge, England, 9 December, 1983. |
| -"The antiviral spectrum of BVDU [(E)-5-(2-bromovinyl)-2'-deoxyuridine]". |
| -Chairman of the Session on "New Data in Viral Chemotherapy" (invited). |
| November 1983 |
EC (European Commission) Workshop on Antiviral Research, |
| Amsterdam, The Netherlands, 25-26 November, 1983. |
| -"Current status of research on BVDU [(E)-5-(2-bromovinyl)-2'-deoxyuridine]" (invited lecture). |
| -Co-Chairman of the Workshop. |
| November 1983 |
WHO (World Health Organization) Meeting on Recent Progress towards the Prevention and Control of Herpesvirus Diseases, Geneva, Switzerland, 14-18 November, 1983. |
| "Chemotherapy of herpesvirus diseases" (invited lecture). |
| 1983 |
Thirteenth International Congress of Chemotherapy, Vienna, Austria, 28 August- |
| 2 September, 1983. |
| -"A review of the new antiherpes agents" (invited lecture). |
| -Chairman of the Session on "New Advances in the Therapy of Herpes Infections" (invited). |
| -"5-Ethyl-2'-deoxyuridine derivatives potentiate the cytotoxicity of cytosine arabinoside analogs for murine leukemia L1210 cells". |
| June-July 1983 |
NATO Advanced Study Institute/FEBS Advanced Course on Targets for the Design of Antiviral Agents, Les Arcs, France, 19 June-2 July, 1983. |
| -"Pyrimidine nucleoside analogues as antiviral agents" (invited lecture). |
| -Organizer, Director and Chairman of the NATO/FEBS Course. |
| June 1983 |
International Symposium on Antiviral Compounds and Wound Healing, Universitäts-Augenklinik Eppendorf, Hamburg, Federal Republic of Germany, 14-16 June, 1983. |
| -"Broad-spectrum antiviral activity of adenosine analogues" (invited lecture). |
| -Chairman of the Session on "Peptides, Antivirals and Wound Healing" (invited). |
| June 1983 |
Eighth Scottish-Scandinavian Conference on Infectious Diseases, Tampere, Finland, 8-11 June, 1983. |
| "Recent developments in antiherpes chemotherapy" (invited lecture). |
| May 1983 |
International Conference on The Physiology and the Pathology of The Interferon System, Slovak Academy of Sciences, Smolenice Castle (near Bratislava), Czechoslovakia, 16-20 May, 1983. |
| "Poly(G).poly(C) as an inducer of interferon" (invited lecture). |
| May 1983 |
Eighth Scandinavian Virus Symposium, Aarhus, Denmark, 4-6 May, 1983. |
| -"Prophylaxis and treatment of viral infections" (invited lecture). |
| -Chairman of the Session on "Prophylaxis and Treatment of Viral Infections" (invited). |
| March 1983 |
Symposium on Antiviral Agents : Chemistry and Biochemistry, organized by the Divisions of Carbohydrate Chemistry and Medicinal Chemistry, 185th National Meeting of the American Chemical Society, Seattle, Washington, USA, 20-25 March, 1983. |
| "Antiviral activity of 5-substituted 2'-deoxyuridines" (invited lecture). |
| December 1982 |
International Symposium on Medical Virology, Anaheim, California, USA, 2-4 December, 1982. |
| "Selective antiherpes drugs" (invited lecture). |
| November 1982 |
International Symposium on Nucleic Acid Chemistry, Kyoto, Japan, 24-26 November, 1982. |
| -"Design of nucleoside, oligonucleotide and polynucleotide analogues as antiviral agents" (invited lecture). |
| -Chairman of Session on "Polynucleotide conformation", (invited). |
| October 1982 |
Fourth International Conference on Comparative Virology, Control of Viral Diseases, Banff, Alberta, Canada, 17-22 October, 1982. |
| "BVDU (bromovinyldeoxyuridine) : current status in antiviral therapy" (invited lecture). |
| September 1982 |
Fifth Beecham Colloquium on Problems of Antiviral Therapy, Medical Society of London, London, England, 15-17 September, 1982. |
| "Prospects for the chemotherapy of herpesvirus infections" (invited lecture). |
| August 1982 |
Eleventh International Carbohydrate Symposium, Vancouver, British Columbia, Canada, 22-28 August, 1982. |
| "Antiviral activity of 5-substituted pyrimidine nucleoside analogues" (invited plenary lecture). |
| May 1982 |
Symposium on Bioorganic Chemistry and Drug Design, USSR Academy of Sciences, Latvian SSR Academy of Sciences, Riga, USSR, 25-29 May, 1982. |
| "Design of nucleoside and polynucleotide analogs as antiviral agents" (invited plenary lecture). |
| April 1982 |
34e Herhalingscursus Kindergeneeskunde, RAI-Congrescentrum, Amsterdam, The Netherlands, 19-24 April, 1982. |
| "Heden en toekomst van chemotherapeutica tegen virale infecties" (uitgenodigde lezing). |
| February 1982 |
Symposium on Trypanocide, fluoreszierende Diamidine, Institut für Pharmazie und Lebensmittelchemie der Friedrich-Alexander Universität, Erlangen-Nürnberg, Federal Republic of Germany, 19-20 February, 1982. |
| "Antiviral and antitumor potentials of diamidine derivatives" (invited lecture). |
| September 1981 |
International Acyclovir Symposium, Wellcome Research Laboratories and National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, 9-11 September, 1981. |
| Chairman of Session on "Animal Studies with Acyclovir" (invited). |
| September 1981 |
Meeting of the European Federation of Child Neurology Societies (EFCNS), St. Catherine's College, Oxford, England, 7-11 September, 1981. |
| "Potentials of new antiviral drugs in the treatment of herpesvirus infections" (invited lecture). |
| August 1981 |
Twenty-Eighth Congress of the International Union of Pure and Applied Chemistry (IUPAC), Vancouver, British Columbia, Canada, 16-21 August, 1981. |
| "Strategies in the design of antiviral drugs" (invited lecture). |
| August 1981 |
Fifth International Congress of Virology, Strasbourg, France, 2-7 August, 1981. |
| -"Inhibitory effect of interferon on the growth of spontaneous mammary tumors in mice" (invited lecture). |
| -"Antiviral potentials of E-5-(2-halogenovinyl)-pyrimidine nucleosides" (invited lecture). |
| July 1981 |
International Workshop on Herpesviruses, Bologna, Italy, 27-31 July, 1981. |
| "Mechanism of anti-herpes action of E-5-(2-halogenovinyl)-2'-deoxyuridines" (invited lecture). |
| July 1981 |
Twelfth International Congress of Chemotherapy, Florence, Italy, 19-24 July, 1981. |
| -"Antiviral activity of sugar-modified derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine" (invited lecture). |
| -Introductory Remarks to Symposium on "Antiherpes Chemotherapy" (invited lecture). |
| -"Therapeutic potentials of BVDU [(E)-5-(2-bromovinyl)-2'-deoxyuridine] as an antiherpes drug" (invited lecture). |
| -Moderator of Session on "New Antiviral Compounds : Laboratory and Clinical Evaluation" (invited). |
| -Organizer and Moderator of Symposium on "Antiherpes Chemotherapy" (invited). |
| June 1981 |
Gordon Research Conference on Purines, Pyrimidines and Related Compounds, Plymouth State College, New Hampshire, USA, 29 June-3 July, 1981. |
| "Evaluation of antiviral agents : antiviral activity of pyrimidine nucleoside analogs" (invited lecture). |
| May 1981 |
Workshop on Genital Herpes/Antiviral Substances, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, 12-13 May, 1981. |
| -"Potentials of bromovinyldeoxyuridine in the treatment of herpes zoster" (invited lecture). |
| -Chairman of Session on "Mechanism of antiviral drugs" (invited). |
| April 1981 |
International Meeting on The Biology of the Interferon System, Erasmus University Rotterdam, The Netherlands, 21-24 April, 1981. |
| "Antiviral potentials of interferon as opposed to other antiviral agents" (invited lecture). |
| March 1981 |
Colloque sur l'Infection Herpétique Humaine et ses Traitements, Faculté de Médecine, Brest, France, 26-28 March, 1981. |
| "Therapeutic potentials of BVDU as an antiherpes drug". |
| February 1981 |
Fourth International Round Table on Nucleosides, Nucleotides and their Biological Applications, Antwerp, Belgium, 4-6 February, 1981. |
| "Antiviral activity of pyrimidine nucleoside analogs : a structure-function analysis" (invited lecture). |
| August 1980 |
Second International Symposium on Antiviral Chemotherapy : Design of Inhibitors of Viral Functions, Universitäts-Augenklinik, Eppendorf, Hamburg, Federal Republic of Germany, 27-29 August, 1980. |
| -"Interferon, Anno 1980" (invited lecture). |
| -"Closing remarks" (invited lecture). |
| August 1980 |
Fifteenth International Congress of Internal Medicine, Hamburg, Federal Republic of Germany, 18-22 August, 1980. |
| Symposium on New Methods of treating viral infections. |
| "New antiviral drugs" (invited lecture). |
| June 1980 |
Fourth International Symposium of Socialist Countries on Antiviral Substances, Szeged, Hungary, 23-25 June, 1980. |
| -"Nucleoside analogues as antiviral agents" (invited lecture). |
| -"Differential inhibition of herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) by (E)-5-(2-X-vinyl)-2'-deoxyuridines". |
| May 1980 |
Negende Vergadering van de Vereniging voor Infectieziekten, Rijksinstituut voor de Volksgezondheid, Bilthoven, The Netherlands, 31 May, 1980. |
| "Antiviral chemotherapy : nucleoside analogues" (invited lecture). |
| April 1980 |
International Symposium on Herpetic Eye Diseases, held by the German Ophthalmologic Society, Augenklinik - Albert Ludwigs Universität, Freiburg, Federal Republic of Germany, 12-14 April, 1980. |
| "On the mechanism of anti-herpes action of E-5-(2-bromovinyl)-2'-deoxyuridine". |
| November 1979 |
Symposium on Developments in Antiviral Therapy, held by the British Society for Antimicrobial Chemotherapy, The London Hospital Medical College, London, England, 30 November, 1979. |
| "(E)-5-(2-bromovinyl)-2'-deoxyuridine : a potent and selective anti-herpes agent". |
| November 1979 |
Gezamenlijke Vergadering van de Vereniging voor Infectieziekten en de Nederlandse Vereniging voor de Studie van Seksueel Overdraagbare Aandoeningen, Eurohal, Maastricht, The Netherlands, 16-17 November, 1979. |
| "Nieuwe anti-herpes preparaten voor klinisch gebruik". |
| October 1979 |
11th International Congress of Chemotherapy and 19th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, Massachusetts, USA, 1-5 October, 1979. |
| "Antiviral activity of 5-(2-halogenovinyl)-2'-deoxyuridines". |
| Moderator of session on "Herpes simplex; Interferon" (invited). |
| Moderator of symposium on "Prevention of infections by herpesviruses" (invited). |
| September 1979 |
Herbsttagung der Gesellschaft für Biologische Chemie, Eberhard-Karls-Universität, Tübingen, Federal Republic of Germany, 26-28 September, 1979. |
| "Antivirale-Nucleosid-Analoge" (invited lecture). |
| May 1979 |
NATO Advanced Study Institute and FEBS Advanced Course on Nucleoside Analogues : Chemistry, Biology and Medical Applications, Sogesta (near Urbino), Italy, 7-18 May, 1979. |
| "Anti-herpes agents with clinical potential". |
| March 1979 |
Symposium on Chemotherapy, held by the Medicinal Chemistry Division of the Royal Netherlands Chemical Society and the Medicinal Chemistry Division of the Flemish Chemical Society, Technische Hogeschool, Eindhoven, The Netherlands, 23 March, 1979. |
| "Antivirale chemotherapeutica" (uitgenodigde lezing). |
| December 1978 |
Planning of NATO Conference on "Nucleoside Analogues : Chemistry, Biology and Medical Applications", University of Birmingham, England, 11-13 December, 1978. |
| September 1978 |
International Symposium on Anti-Herpes-Virus-Chemotherapy : Experimental and Clinical Aspects, Universitäts-Augenklinik Eppendorf, Hamburg, Federal Republic of Germany, 7-9 September, 1978. |
| "Pyrimidine nucleoside analogues which selectively inhibit herpes simplex virus replication" (invited lecture). |
| "Concluding remarks" (invited lecture). |
| July 1978 |
Twelfth Meeting of the Federation of European Biochemical Societies (FEBS), Post-Congress Symposium on Antimetabolites in Biochemistry, Biology and Medicine, Prague, Czechoslovakia, 10-12 July, 1978. |
| "Comparative study of the potency and selectivity of anti-herpes compounds" (invited lecture). |
| June 1978 |
Workshop on the Development of Antivirals, Antiviral Substances Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, 29-30 June, 1978. |
| "New antivirals" (invited lecture). |
| March 1978 |
NATO International Advanced Study Institute on Antiviral Mechanisms for the Control of Neoplasia, Corfu, Greece, 15-25 March, 1978. |
| "Interferon induction by synthetic polynucleotides : recent developments" (invited lecture). |
| "Inhibition of oncornavirus activities by polynucleotide analogues" (invited lecture). |
| December 1977 |
Tenth Anniversary Symposium of the Nucleotide Group of the Chemical and Biochemical Societies on Nucleoside and Polynucleotide Synthesis and Structure, Birmingham, England, 20-21 December, 1977. |
| "Antiviral activity of (S)-9-(2,3-dihydroxypropyl)adenine". |
| October 1977 |
Planning of NATO Conference on "Nucleoside Analogues: Chemistry, Biology and Medical Applications", Max-Planck-Institut für Experimentelle Medizin, Göttingen, Federal Republic of Germany, 17-19 October, 1977. |
| September 1977 |
Round Table Conference on Antiviral Chemotherapy, Sandoz Forschungsinstitut, Vienna, Austria, 26 September, 1977. |
| "Antiviral agents with clinical potential" (invited lecture). |
| September 1977 |
Tenth International Congress of Chemotherapy, Zürich, Switzerland, 18-23 September, 1977. |
| "Uses and production of exogenous interferon in man" (invited lecture). |
| "Antiviral activity of novel deoxyuridine derivatives". |
| "Broad-spectrum antiviral activity of pyrazofurin (pyrazomycin)". |
| June 1977 |
Symposium on the Preparation, Standardization and Clinical Use of Interferon, Yugoslav Academy of Sciences and Arts, Institute of Immunology, Zagreb, Yugoslavia, 8-9 June, 1977. |
| "Novel polynucleotide inducers of human interferon" (invited lecture). |
| May 1977 |
Fifth Aharon Katzir-Katchalsky Conference on Interferons and the Control of Cell-Virus Interactions, The Weizmann Institute of Science, Rehovot, Israel, 26 May, 1977. |
| "Novel polynucleotide inducers of human interferon" (invited lecture). |
| October 1976 |
First Cleveland Symposium on Macromolecules (Structure and Properties of Biopolymers), Case Institute of Technology, Case Western Reserve University, Cleveland, Ohio, USA, 11-15 October, 1976. |
| "Polynucleotides as inducers of interferon" (invited lecture). |
| July 1976 |
Microwave Power Symposium 1976, Katholieke Universiteit Leuven, Belgium, 27-30 July, 1976. |
| "Effect of microwaves on virus multiplication in mammalian cells in vivo and in vitro". |
| "Effect of microwaves combined with interferon and/or interferon inducers (poly I.poly C) on development of sarcoma 180 in mice". |
| May 1976 |
Symposium on Synthetic Nucleosides, Nucleotides and Polynucleotides, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Deutschland, 3-5 May, 1976. |
| "Antiviral activity of novel nucleoside analogs" (invited lecture). |
| November 1975 |
12de Vergadering van de Belgisch-Nederlandse Infectieziekten Club, U.I.A. (Universitaire Instelling Antwerpen), Antwerpen, Belgium, 22 November, 1975. |
| "Antivirale bestanddelen in de behandeling van experimentele herpes encephalitis". |
| October 1975 |
Symposium on Clinical Use of Interferon, Yugoslav Academy of Sciences and Arts, and the Institute of Immunology, Zagreb, Yugoslavia, 1-2 October, 1975. |
| "Encephalitis induced upon intranasal challenge of mice with herpes simplex virus : experimental model to assess the clinical efficacy of interferon administered exogenously". |
| August 1975 |
Symposium on Antivirals with Clinical Potential, Stanford University, Stanford, California, USA, 26-29 August, 1975. |
| "Intranasal challenge of mice with herpes simplex virus : experimental model for evaluating the efficacy of antiviral drugs". |
| July 1975 |
European Molecular Biology Organization (EMBO) Workshop on Interferon, Department of Biological Sciences, University of Warwick, Warwickshire, England, 29-31 July, 1975. |
| "Interaction of polynucleotides with the cell" (invited lecture). |
| March-April 1975 |
International Workshop on Interferon in the Treatment of Cancer, Memorial |
| Sloan-Kettering Cancer Center, New York, USA, 31 March-2 April, 1975. |
| "Cytostatic effect of interferon on mouse melanoma cells. A preliminary report" (invited lecture). |
| "Interferon induction by poly(I).poly(C) analogues in rabbit kidney cells and human skin fibroblasts" (invited lecture). |
| "Non-antiviral activities of interferon : not controlled by chromosome 21" (invited lecture). |
| October 1974 |
Joint Meeting of the Biochemical Societies of Belgium, the Federal Republic of Germany and The Netherlands, Düsseldorf, Deutschland, 2-5 October, 1974. |
| "Inhibition of mouse leukemia virus RNA dependent DNA polymerase by 2'-OH substituted polynucleotides". |
| April 1974 |
89th Meeting of the Belgian Society of Biochemistry (réunion commune avec la "Société de Chimie Biologique"), Leuven, Belgium, 18-19 April, 1974. |
| "Previously unrecognized interactions among synthetic homopolynucleotides and their complexes revealed by interferon induction studies". |
| January 1974 |
Symposium on Interferon, organized by the Society for General Microbiology, Leicester, England, 3-4 January, 1974. |
| "Does poly(I).poly(C) have to enter the cell in order to stimulate interferon production" (invited lecture). |
| "Interferon induction by polynucleotides" (invited lecture). |
| October 1973 |
Konferenz der Gesellschaft für Biologische Chemie on Nucleosid- und Nucleotid-Analoga under ihre Anwendung, Friedrichsdorf/Taunus, Deutschland, 3-6 October, 1973. |
| "Interferon induction by synthetic polynucleotides : structure-function relationship" (invited lecture). |
| September 1973 |
Table Ronde Roussel UCLAF on Control Mechanism in Interferon Formation and Action, Paris, France, 24-25 September, 1973. |
| "Interferon induction by synthetic polynucleotides : structural requirements and mechanisms" (invited lecture). |
| September 1973 |
Gulbenkian Meeting on Interferon, Oeiras, Portugal, 19-21 September, 1973. |
| "Interferon induction by synthetic polynucleotides : competition between inactive and active polymers" (invited lecture). |
| April 1973 |
European Molecular Biology Organization (EMBO) Interferon Course, School of Molecular and Biological Sciences, University of Warwick, Warwickshire, England, 2-13 April, 1973. |
| "Mechanism of polynucleotide induced interferon formation" (invited lecture). |
| October 1972 |
International Interferon Workshop, Williamsburg, Virginia, USA, 18-20 October, 1972. |
| "Role of the outer cell membrane in interferon induction by synthetic polyribonucleotides" (invited lecture). |
| "Increased toxicity of double-stranded RNA in interferon-treated cells and virus-infected animals" (invited lecture). |
| September 1971 |
Second National Symposium on Nucleic Acids, Bucharest, Rumania, 27-28 September, 1971. |
| "On the mechanism of interferon production and antiviral activity of synthetic polyribonucleotides". |
| September 1971 |
Seventh Meeting of the Federation of European Biochemical Societies, Varna, Bulgaria, 20-25 September, 1971. |
| Symposium on Virus-Cell Interactions and Viral Antimetabolites. |
| "Synthetic polynucleotides and interferon induction" (invited lecture). |
| September 1971 |
International Colloquium on Interferon and Interferon Inducers, The Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium, 13-16 September, 1971. |
| "Mechanism of the priming effect of poly rI on the antiviral activity of poly rC". |
| June 1971 |
Second International Congress for Virology, Budapest, Hungary, 27 June-3 July, 1971. |
| "Nucleic acids as interferon inducers" (invited lecture). |
| March 1971 |
European Molecular Biology Organization (EMBO) Workshop on Interferon, School of Molecular and Biological Sciences, University of Warwick, Warwickshire, England, 16-18 March, 1971. |
| "Mechanism of interferon induction" (invited lecture). |
| October 1970 |
Tenth Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, Illinois, USA, 19-21 October, 1970. |
| "Studies on the mechanism of antiviral protection and interferon production by bis-DEAE-fluorenone in the mouse". |
| September 1970 |
Symposium on Drugs and Cell Regulation, The Roswell Park Memorial Institute, Buffalo, New York, USA, 23-25 September, 1970. |
| "Chemically defined non-viral interferon inducers : structural requirements and mechanisms" (invited lecture). |
| August 1970 |
Tenth International Congress for Microbiology, Mexico City, Mexico, 9-15 August, 1970. |
| "The role of interferon in the protective effect of (poly rI).(poly rC) against intranasal vesicular stomatitis virus challenge in mice". |
| October 1969 |
Ninth Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, D.C., USA, 27-29 October, 1969. |
| "Interferon induction by and ribonuclease sensitivity of thiophosphate-substituted polyribonucleotides". |
| June 1969 |
Second Conference on Antiviral Substances of the New York Academy of Sciences, New York, USA, 16-19 June, 1969. |
| "Structural requirements for synthetic polyanions to act as interferon inducers" (invited lecture). |
| "The interferon inducer from Brucella" (invited lecture). |
